Odds on Open

Ethan Kho interviews David Orr, a former professional poker player turned hedge fund manager. They discuss David's journey from poker to founding Militia Capital, his investment philosophy, and the lessons learned from both industries. David shares insights on risk management, the importance of finding asymmetric bets, and the challenges of the hedge fund industry. He also offers advice for as...

Discover how top multi-manager hedge funds like Citadel and Millennium attract the brightest minds, the evolving talent strategies in the industry, and the unique traits that set successful candidates apart. Whether you're an aspiring finance professional or just curious about the inner workings of hedge funds, this episode offers valuable insights into the competitive landscape of financial s...

What’s the difference between prediction markets trading and equities trading? On Odds on Open, the world’s #1 prediction markets trader Domer explains how prediction markets work as a form of information-based trading, where news and signals can arrive at any moment, forcing continuous price discovery and repricing. Unlike stock markets, where returns often depend on long-term growth, valuation m...

❗ACCESS OPPORTUNITIES EXCLUSIVE TO OOO VIEWERS: https://app.youform.com/forms/e2jpsj4z ❗ How do top hedge funds actually hedge trades? At SIG, traders were often told not to hedge. Most assume elite trading firms hedge every position, but Susquehanna (SIG) built its edge by avoiding hedging when trades had positive expected value (EV). Kris Abdelmessih—who later moved into portfolio management r...

In this episode, former Tower Research and Flow Traders quant Annanay Kapila breaks down the reality of high frequency trading, HFT strategies, and top automated trading systems. He explains what quant researchers actually do inside elite firms—where world-class math talent competes in a true zero-sum market. Annanay goes deep into market making strategies, latency engineering, alpha generation, a...

Former Citadel MD Michael Watson gives a direct look inside a multi-strategy hedge fund and what it was like working under Ken Griffin. He breaks down Citadel’s pod-shop model, its high-intensity capital allocation frameworks, and how Ken built a concentration of talent across quant trading, quant research, engineering in quant, discretionary equities, Python/C++, data engineering, and alternative...

What’s it like being a trader at SIG? At Susquehanna International Group, Todd Simkin has trained some of the world’s best traders using poker strategy, probabilistic games, and decision-making under uncertainty that mirror real-world quantitative trading. In this episode, Todd breaks down how SIG teaches trading interns Bayesian updating, asymmetric information, market microstructure awareness, a...

John Knorring spent over a decade on the Goldman Sachs trading floor, leading natural gas trading through the 2000s—a period defined by trading in a financial crisis, Hurricane-driven volatility, the Amaranth blow-up analysis, and trading during 2008 when bank desks had to price massive option books overnight. He explains how bank trading desks, pit traders, handwritten tickets, and early prop tra...

How do you start a hedge fund—and where should you launch it? Daniel Xystus has done both. From Los Angeles quant to Chicago portfolio manager to CIO in Hong Kong and the Middle East, Daniel now helps new hedge fund managers navigate fund setup, regulation, and operations. We break down what it really takes to launch a hedge fund—choosing your fund domicile, building professional infrastructure, a...

How do top quantitative trading firms use generative AI?  @versorinvestments  , a $1.4B[1] quantitative investment boutique in the asset management industry, reveals how human ingenuity drives its AI-powered investment research and machine learning in finance pipeline. Partners DeWayne Louis and Nishant Gurnani explain how they combine supervised machine learning, natural language processing, and...

Doug Garber, former Citadel hedge fund analyst and Millennium Management portfolio manager, joins the show to unpack what it’s really like inside two of the world’s top multi-manager hedge funds — and how each approaches portfolio construction, risk management, and hedge fund culture. Drawing from his years working at Citadel and working at Millennium, Doug explains why Citadel operates more like...

Why do smart investors lose money? Alix Pasquet, Managing Partner of Prime Macaya Capital Management, breaks down the paradox at the heart of hedge fund investing psychology—why high IQ often hurts investors more than it helps. Drawing on decades of experience allocating to top quant funds and running capital, Alix explains how hedge fund managers fall into classic strategy mistakes, why competing...

How do you find trading edge in electricity markets? Cory Paddock, co-founder of GBE, explains how real alpha generation in power trading comes from anticipating paradigm shifts before the market sees them. In a renewable energy trading market shaped by constant regime change—coal replaced by gas, wind and solar reshaping grid topology, and data centers driving new load volatility—edge belongs to...

Can you start a hedge fund as a college student? Christina Qi, co-founder of Domeyard, did—and later built Databento, a modern market data API used by top algorithmic trading and quantitative trading teams. We get into how high-frequency trading (HFT) actually works, why clean order book/tick market data matters for robust trading strategies, and how a product-led model beats “talk-to-sales.” Chri...

Should you invest in the S&P 500, or look for smarter ways to beat the market? Jason Hsu, Co-Founder of Research Affiliates ($159B AUM) and now CIO of Rayliant, explains why simply buying the index or asking “should I invest in ETFs” isn’t enough. In this episode, he breaks down smart beta vs S&P 500, systematic investing, and how factor investing strategies and fundamental indexing can de...

Can you trade the stock market with AI? Yes: Renee Yao launched Neo Ivy Capital, a billion-dollar** AI hedge fund that uses AI in trading and investing to generate alpha. In this episode of Odds on Open, she explains how she built a quant hedge fund from scratch, scaling to over $1B AUM** with advanced AI hedge fund strategies that adapt to markets in real time and show how to trade stocks with ar...

In this episode of Odds on Open, Ethan Kho sits down with Joe Mezrich, Founder of Metafoura LLC and former Managing Director at Nomura Quant Strategies, to reflect on nearly 40 years in quant finance. Joe’s career spans the early days at Salomon Brothers—where he helped pioneer factor models, risk modeling, and even early machine learning in finance—through senior sell-side research roles at Morga...

Former Cargill Global Trading & Risk Management Director Kristine Engman Hochbaum explains how commodities trading strategies and quant trading strategies really work. On Odds on Open, she breaks down the sources of trading edge and alpha generation in today’s commodities markets, from agriculture trading to energy and metals. We cover why physical vs. financial commodities trade differently,...

This week, Ethan Kho sits down with Dr. Ernest P. Chan — former quant at Millennium and Morgan Stanley, and now founder of PredictNow.ai and QTS Capital Management. Ernie is one of the best-known voices in quant finance, author of Quantitative Trading, and a pioneer in systematic trading strategies. We cover:- When machine learning trading models work in markets — and when they fail- Why financial...

In this episode of Odds on Open, Ethan Kho sits down with Vinesh Jha, founder of Extract Alpha and former director of PDT Partners, to unpack lessons from the 2007 Quant Quake and how systematic investors can adapt in today’s crowded landscape. We cover:- What really happened inside PDT Partners when the firm lost $500M during the Quant Quake- Why so many quant hedge funds blew up in 2007 — and th...

What’s it really like working as a quant in fundamental research at Two Sigma—and how will AI, LLMs, and agentic workflows change quantitative trading strategies? Bill Mann, former Two Sigma fundamental researcher and founder of Harmonic Insights, joins Ethan Kho to break down how hedge funds build edge from widely available data and why “hacker” creativity still matters in systematic investing. B...

Can you analyze social media for investment decisions? How do hedge funds use Reddit posts, earnings calls, and SEC filings to find alpha? What’s the role of LLMs for financial analysis in 2025? Chris Kantos, Head of Quantitative Research at Alexandria Technology, joins us to explain how the buy side uses natural language processing (NLP), AI for investing, and text-based sentiment data to generat...

Financial markets are a game, says Grant Stenger. So how do you win in the financial markets? Grant, a former Jane Street intern and current crypto founder, believes markets are the most competitive game on earth—and he's been training to beat them since high school. From card counting in middle school to landing a hedge fund internship at QuantRes before university, Grant shares how a lifelong ob...

How do you become a solo quant trader and build your own systematic trading business? Robert Carver, ex-head of fixed income at Man AHL—a $63 billion systematic trading hedge fund—shares how he went from managing institutional capital to becoming an independent, full-time quant trader. He reveals the key skills, mindset, and tools needed to succeed in quant trading without working at a big firm, h...

What is edge in trading—and how do hedge funds and quant traders find edge in 2025? According to Agustin Lebron, former quant trader at Jane Street and author of The Laws of Trading, edge is what separates average traders from those who thrive at a top hedge fund. But today, finding edge requires more than just a good model—it demands judgment, adaptability, and a deep understanding of how quant t...