NPR All Things Considered

Researchers have been chasing the dream of a cancer vaccine for decades. Some recent successes with mRNA technology are garnering excitement from patients, doctors, government and investors.

One patient in a small trial is experiencing the fantasy results so far with an mRNA pancreatic cancer vaccine. She shows no evidence of the cancer that was supposed to kill her years ago.

The U.S. has become more politically polarized, but research shows people overestimate their differences and there is 'messy middle' majority of Americans who share overlapping political views.

Andy Taeger & James Purcell are trying to become the first people ever complete the board game Campaign for North Africa. The is so complex it could take decades to finish.

In Chile's storied port city of Valparaíso, a new generation is breathing life into boleros, waltzes and cueca, blending the city's musical traditions with sounds of today.

Republicans started the year believing tax cuts would benefit them in the midterms. Instead other affordability issues are driving voters to Democrats.

Sometimes hospitals invite special guests to come visit patients in an effort to boost spirits. One "mane" attraction at an Ohio hospital is Willie Nelson- the pony.

Political conspiracy films peaked in the 1970s. What do those films offer at a time when conspiracy theories flood social media and are repeated by the president and other politicians?

Qatar has been leading intense mediation efforts over the past 72 hours to prevent a new round of possible U.S. attacks on Iran after Tuesday's midterm elections. The uncertainty has the entire Gulf region on edge.

Rep. Haley Stevens was scheduled to attend a unity event today with Abdul El-Sayed, who beat her in the Democratic primary. Instead, she endorsed his Republican opponent, Mike Rogers.

Communities in the Southwest are bracing for more flooding this weekend. This follows weeks of devastating storms that have pummeled parts of the region.

Democrats are putting up a fight in midterm races this year that went for President Donald Trump by double digits in 2024. Kentucky Public Radio's Sylvia Goodman explains what we can learn from one Kentucky district.

There was a mixed Halloween bag of economic news this week. GDP growth is up, but so are prices. For now at least, interest rates are staying the same. What does that mean for the midterm elections?

U.S. Secretary of State Marco Rubio is hosting the G20 foreign ministers' meeting in Atlanta, with a focus on economic and security challenges.

NPR's Sacha Pfeiffer speaks with Jazz pianist Joe Alterman about his podcast The Upside of Jazz from NPR member stations WABE in Atlanta.

A new local government has taken its seat in the southern Philippines, in a step that marks a milestone in the peace process for a conflict that has lasted some 80 years.

Some election officials have been notified that the DOJ will be monitoring their polling stations. NPR's voting correspondent Miles Parks explains what he's watching for on election day - and afterwards.

What does it take to create a horror movie scream that is truly horrifying? One that makes the hair on the back of your neck stand up? NPR's Michelle Aslam found it is part art and part science.

The legacy of magician Harry Houdini still looms large in Detroit 100 years after his death there. Some mark the anniversary of Houdini's death by trying to make contact with his spirit.

Recent analysis from research nonprofit Climate Central found that on average, fall temperatures have warmed by 2.9 degrees Fahrenheit in the U.S. and the summer heat is lasting longer.

NPR's Scott Detrow speaks with reporter Megan Johnson, who wrote about what it's like to live in Salem, Mass. — famous for the Salem Witch Trials — during Halloween tourism season.

Over the last few months, 100 randomly selected people tested whether a random bunch of citizens can work together to fix property taxes, avert a future budget crisis, and maybe reinvent democracy.

NPR podcast Machine Gods is about the AI revolution. Hosts Kevin Roose and Casey Newton take questions from listeners about AI.

Emily Kwong and Ari Daniel of NPR's Short Wave talk about mysterious X-ray objects, the link between movement and learning and how a small part of the brain triggers memory formation.

Esther Perel is a famous psychotherapist and host of the podcast Where Should We Begin . She told Wild Card 's Rachel Martin that her parents' experience as holocaust survivors shaped her worldview.