Neurosalience

The discovery of resting state fMRI ushered in an entirely new subfield of fMRI and a new era in functional imaging that permeates much of what we do today. Today’s guest, Professor Bharat Biswal is credited with the discovery of this signal. In this conversation Professor Biswal recounts the events leading up to and including his discovery of the resting state signal. He and Peter also talk about...

This week on #Neurosalience, we discuss an exciting new paper published in Science on October 14 2022 that caused quite a stir, titled: In vivo direct imaging of neuronal activity at high temporospatial resolution . In this paper, they show clear maps and timecourses of directly measured neuronal activity as it occurs, at 5 milliseconds resolution. This interview is with professor Jang-Yeon Park w...

This week on Neurosalience, something a little different: a live podcast recorded at the OHBM 2022 Annual Meeting featuring a continuation of a discussion of the recent paper "Reproducible brain-wide association studies require thousands of individuals" by Scott Marek et al. This paper set the stage for some great discussions about what it means for the field and its broader implications for brain...

This week on #Neurosalience, we discuss one very cool and very useful fMRI acquisition strategy called Multi-echo EPI. While it’s been around for over 20 years, only a fraction of papers reporting fMRI results have used it. It can help quite a bit towards increasing sensitivity, mitigating signal dropout and motion artifacts, and stabilizing the time series to allow for tracking of very slow chang...

Welcome a brand-new season of Neurosalience! In this episode, Peter Bandettini speaks with new podcast production lead Alfie Wearn about the podcast, the changes this season, and what we can look forward to in season 3. Please send any feedback, guest suggestions, or ideas to ohbm.comcom@gmail.com Episode producers: Alfie Wearn Anastasia Brovkin Stephania Assimopoulos. Brain Art Artist: Sina Manso...

In this bonus episode, Peter Bandettini talks to four co-authors from a recent Nature paper on “Reproducible brain-wide association studies require thousands of individuals.” Scott Marek , Brenden Tervo-Clemmens , Damien Fair and Nico Dosenbach discuss their work, demonstrating that to make reproducible associations between MRI measures (both structural and functional) and behavioral measures, upw...

Over the thirty-nine episodes of this podcast, Peter Bandettini, PhD (twitter: @fmri_today ), has guided interesting conversations with brain scientists of all types about the latest developments, controversies, findings, and challenges in the field of brain mapping. Of course, Dr. Bandettini is an impressive and fascinating scientist in his own right, so we on the Neurosalience production team th...

Eric Wong is Professor and Associate Director for Imaging Hardware at the University of California, San Diego. He received his Ph. D. in Biophysics in 1991 from the Medical College of Wisconsin where he was the key person in starting fMRI at the Medical College of Wisconsin.  In this podcast, Eric and Peter start by revisiting when they first met and the flurry of excitement and activity when...

Randy McIntosh, Ph. D. has been a scientist at the Rotman Research Institute of Baycrest Centre at the University of Toronto since 1994 and, since the start of 2022, is the new Director of the Simon Fraser University Institute for Neuroscience and Neurotechnology in Burnaby British Columbia - just outside of Vancouver. Randy obtained his PhD in 1992 from the University of Texas at Austin in Psycho...

Today we are discussing the general question of how neuroimaging (and mostly fMRI) fit into the landscape of neuroscience research approaches. More specifically we discuss the question of what, over the years, has neuroimaging taught us about the brain? In this fascinating discussion, we work through many related topics and get a solid sense of Dr. Passingham’s perspectives on these - including hi...

In this episode Dr Peter Bandettini and co-host Dr Brendan Ritchie interview Dr Grace Lindsay. They find out about her new book 'Models of the mind' and about the process of writing a book. In doing so, they consider different types of brain models, from simply descriptive to more mechanistic, from too simple to overfitted. They describe the challenge in neuroscience of network modelling - the man...

In this episode, we discuss what was important to Pedro early in his career. He describes his first forays into clinical use of EEG back in the 70s and then we go on to discuss some of his highly creative work in deeply interpreting EEG signals today. Later we discuss his current visiting position in Chengdu, China and a growing EEG database as well as his international consortium. We touch briefl...

Peter talks to Dr. Lucina Uddin about the constant struggle shared by all scientists in the field of neuroimaging to find the right paradigms, acquisition tools, and analysis approaches to add insight into fundamentals of brain organization and how it relates to behavior. They talk about cognitive flexibility, Autism, the salience network, and the need for an ontology of network nomenclature so th...

Functional MRI is a profoundly successful and powerful technique that so many of us use. It’s still developing and adding to our insight about the human brain. While MRI was developed in the late 1970’s and early 80’s, it would be another decade before it was realized that MRI could be used to detect and map, non-invasively, human brain activation. My guests today, Ken Kwong, Bob Turner, and Ravi...

Maurizio Corbetta is Full Professor and Chair of Neurology in the Department of Neuroscience at the University of Padua, Italy. He is also the founding director of the new Padua Neuroscience Center, a highly interdisciplinary research programme centered on the idea of brain networks in health and society. After receiving is M.D. from the University of Pavia in Italy, he carried out a residency in...

Guest: Anastasia Yendiki is a faculty member at the MGH Martinos center and a member of the Laboratory for Computational Neuroimaging (LCN) .  Her background is in statistical signal and image processing. She received her Ph. D. in Electrical Engineering from the University of Michigan at Ann Arbor, where she worked on inverse problems in tomographic reconstruction for nuclear imaging . As a...

Denis LeBihan , M.D., Ph. D., is a clinician and physicist, a relentless innovator in the field of MRI and fMRI since the late 80’s, and—as we hear in this podcast—a broad, deep, and highly creative thinker who remains passionate about his work. Denis is the founding director of NeuroSpin in Orsay, France and spends time in Japan as a guest professor at the University of Kyoto and National Institu...

In this episode Peter Bandettini speaks with the Chairs of three large neuroimaging societies: Randy Gollub from the Organization for Human Brain Mapping (OHBM), Fernando Calamante from the International Society for Magnetic Resonance in Medicine (ISMRM) and Ron Mangun from the Cognitive Neuroscience Society. Together they consider how COVID-19 has impacted the annual meetings of these societies a...

Dr. Xavier Castellanos is a psychiatrist and a highly influential scientist who has been working in neuroimaging for over 20 years towards the goal of leveraging MRI, fMRI and other approaches to better understand and treat children and adults with psychiatric disorders. Xavier Castellanos studied Chomskian linguistics at Vassar College, experimental psychology at the University of New Orleans, an...

In this episode Peter Bandettini meets with Drs Lieneke Janssen and Gisela Govaart to discuss grassroots open science projects. They consider how Lieneke & Gisela got started, what is unique about their group (that it is purely student/postdoc driven), what initiatives they are taking on, the need for open science, and how to incentivize people to embrace open science. For more info on the Neu...

This is our second episode with Jack Gallant, PhD, a neuroscientist and engineer. Jack is currently a Chancellor’s Professor of Psychology and Class of 1940 Endowed Chair at UC Berkeley and is affiliated with the Department of Electrical Engineering and Computer Science. The first podcast with him delved so deeply into his approach to assessing fMRI data and his philosophy of doing good science an...

MRI is ultimately about separating a known but variable signal from highly variable noise. How one does this makes all the difference. fMRI is particularly challenging since what is signal and what is noise is not always clear, as they both vary in time and space. In this episode, Peter talks to Jack Gallant, PhD, a neuroscientist and engineer. Jack is currently a Chancellor’s Professor of Psychol...

Peter talks to Bob Cox, Ph. D., Gang Chen, Ph. D. and Paul Taylor, Ph. D. about AFNI. AFNI is a major processing package used by brain mapping groups all over the world. It is nearly as old as fMRI itself, and has been steadily growing in functionality. Here we discuss the history of how it all started as well as a few of the challenges of fMRI processing that have arisen over the years. Important...

Peter talks to Dr. Nikola Stikov, a professor of Biomedical Engineering, a researcher at the Montreal Heart Institute, and co-director of NeuroPoly, the Neuroimaging Research Laboratory at Polytechnique Montreal. Nikola is a physicist, engineer and a strong proponent of quantitative and reproducible MRI for further clinical traction and impact. This involves promoting open science, creating shared...

This week, Peter talks to Dr. Melanie Boly, a neurologist and neuroscientist who has worked for more than fifteen years in the field of altered states of consciousness such as vegetative state, sleep and anesthesia. In this wide ranging discussion, Peter and Melanie address everything related to her work on consciousness.  They start with some of her early work on resting state as a modulator...