NeuroFrontiers

Guest: Nicholas J. Silvestri, MD FcRn inhibitors provide a targeted approach to generalized myasthenia gravis (gMG) treatment by reducing pathogenic antibodies. These therapies offer fewer side effects compared to traditional treatments like corticosteroids, improving both disease control and quality of life. Dr. Nick Silvestri, a Professor of Neurology at the University of Buffalo Jacobs School o...

Guest: Henry Kaminski, MD Generalized myasthenia gravis (gMG) is a complex autoimmune disease with a wide range of symptoms, from ocular issues to severe muscle weakness. As our understanding of the pathophysiology behind gMG evolves, so does our ability to improve patient management. Join Dr. Henry Kaminski as he examines emerging advancements in gMG treatment, including FcRN inhibitors and immun...

Guest: Kelly G. Gwathmey, MD ALS can take up to a year to diagnose, but researchers are hard at work trying to find ways to minimize diagnostic delays and errors. One such solution is the Rapid Access ALS Clinic, where patients were diagnosed an average of two months sooner. Here to talk about this work is Dr. Kelly Gwathmey, Professor of Neurology at the Virginia Commonwealth University School of...

Guest: John Brandsema, MD As patients with Duchenne muscular dystrophy (DMD) age, their treatment regimens, considerations, and goals change. That’s why Dr. John Brandsema is here to talk about how we can best treat and support patients with DMD throughout their entire care journey. Dr. Brandsema is the Neuromuscular Section Head at the Children’s Hospital of Philadelphia.

Guest: John Brandsema, MD Between 60 and 70 percent of patients with Duchenne muscular dystrophy (DMD) also have a diagnosable neurobehavioral phenotype like autism, ADHD, and anxiety. Here to talk about these common neurobehavioral issues in patients with DMD and how we can manage them is Dr. John Brandsema, Neuromuscular Section Head at the Children’s Hospital of Philadelphia.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: John Brandsema, MD The gene therapy delandistrogene moxeparvovec was recently approved for patients with Duchenne muscular dystrophy (DMD) who are at least 4 years old. This expanded approval is based on the efficacy and safety results from the EMBARK trial. Joining Dr. Charles Turck to break down those key findings and the implications of this advan...

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Jasmohan Bajaj, MD Around 50 percent of people with cirrhosis have hepatic encephalopathy, which means some kind of brain dysfunction. As these patients age, it gets more and more difficult to differentiate between hepatic encephalopathy and dementia, which is why two recent studies sought to uncover how many patients with dementia have undiagnosed c...

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Dr. Robert J. Shmookler Reis, PhD Guest: Dr. Srinivas Ayyadevara, PhD Numerous factors could predispose patients to the progression of mild cognitive impairment or dementia and Alzheimer’s disease. Fortunately, a recent study found that a cholesterol-lowering medication called ezetimibe might help reduce the risk of Alzheimer’s disease progression an...

Host: Ashley Baker, MSN, PMHNP Guest: Istvan Mody, PhD The objective of this study around Alzheimer’s disease was to enhance oscillations in laying down memory traces and cognition. Using mice, the human APOE 4 gene was inserted into them, so they replicated similar events that take place in Alzheimer’s patients, and other mice were treated with DDL-920. The hope is to move on to human patients an...

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Nadia Merchant, MD Guest: Melody Shi, MD Guest: Despoina Galetaki, MD Steroids are one of the main treatments for patients with Duchenne muscular dystrophy (DMD), but prolonged steroid use can come with many endocrine side effects, like weight gain, insulin resistance, and adrenal insufficiency. To learn more about these endocrine complications and s...

Guest: Mar Tintore, MD At this year’s European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) conference, learn about a presentation on the new criteria for diagnosing multiple sclerosis (MS) patients with Dr. Mar Tintoré, President of ECTRIMS and Clinical Coordinator of the Multiple Sclerosis Centre of Catalonia Cemcat at the Hospital Vall d’Hebron in Barcelona, Spain.

Guest: Mar Tintore, MD A special guest will be joining the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2024 annual meeting on opening day. To learn more about the impact ECTRIMS has had on multiple sclerosis patients over the last 40 years, tune in with Dr. Mar Tintoré, President of ECTRIMS and Clinical Coordinator of the Multiple Sclerosis Centre of Catalonia Cem...

Guest: Mar Tintore, MD The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2024 annual meeting is celebrating its 40 th anniversary in Copenhagen, Denmark. 9,000 delegates from all over the world are expected to attend this multiday event, which will include keynote lectures, poster sessions, and selected scientific and educational sessions, as well as plenty of phila...

Host: Ashley Baker, MSN, PMHNP Guest: Kathleen Nadeau, PhD Girls and women with ADHD are often underdiagnosed and undertreated compared to boys and men, which puts them at risk of serious issues like unplanned pregnancies, cigarette smoking, and even anxiety and depression. To help us better identify and manage girls and women with ADHD, psychiatric nurse practitioner Ashley Baker speaks with Dr....

Guest: Kathleen Nadeau, PhD It’s important to be aware of the different ways ADHD impacts girls and women compared to boys and men, which is why Dr. Kathleen Nadeau is here to help shed light on those differences. Dr. Nadeau is the Founder and Clinical Director of the Chesapeake Center for ADHD Learning and Behavioral Health in Bethesda, Maryland.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Kay Davies, PhD, DBE FMedSci FRS Duchenne muscular dystrophy ( DMD ) is a genetic disorder characterized by the progressive loss of muscle, and it primarily occurs in young boys. And since t here’s currently no cure, recent therapeutic advancements are aimed at improving symptoms and patient ’s quality of life. Dive in to review th e therapeutic land...

Host: Ashley Baker, MSN, PMHNP Guest: David Goodman, MD, LFAPA ADHD is a lifelong disorder, but its symptoms like memory and concentration difficulties can often be misinterpreted as normal functions of aging. So to help address this misunderstanding, psychiatric nurse practitioner Ashley Baker speaks with Dr. David Goodman about essential diagnostic and treatment strategies for older adults with...

Host: Ashley Baker, MSN, PMHNP Guest: Timothy Wilens, M.D. The treatment journey for ADHD typically begins in childhood, but therapy interventions must be modified as our patients transition into adulthood. So how do we support our patients along this continuum? Tune in for a discussion on ADHD treatments and the difficulties that result in a missed pediatric diagnosis with psychiatric nurse pract...

Host: Karima Benameur, MD According to recent data, nutrition plans like the Mediterranean, DASH, and MIND diets can help patients with a variety of neurological diseases, including multiple sclerosis, stroke, and dementia. Tune in to hear Dr. Karima Benameur discuss this research and how we can counsel patients with neurological diseases about nutrition. Dr. Karima Benameur is an Associate Profes...

Host: Ashley Baker, MSN, PMHNP Guest: Stoni Johnston, APRN, MSN, PMHNP-BC Insomnia is one of the common issues HCPs see in patients with ADHD, and narcolepsy can also have similar presentations of ADHD. So how can we accurately diagnose ADHD from a sleep disorder? Dive in as Psychiatric Nurse Practitioner Ashley Baker is joined by Stoni Johnston, Psychiatric Nurse Practitioner and Founder of Sulca...

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Lauren Treat, MD Guest: Wendy Gaultney, MD Children who have neurological disorders and experience pain are often not able to articulate how their pain affects them. That’s why it’s important for clinicians to understand the brain’s role in the experience of pain and how to help these patients and their families navigate their pain. Joining Dr. Charl...

Host: Ashley Baker, MSN, PMHNP Guest: Margaret Sibley, PhD In the years following the COVID-19 pandemic, clinicians saw the biggest increase in patients 25 years and older seeking help for ADHD. And even though healthcare providers aren’t entirely sure where this trend came from, research shows that a lot of ADHD care went to telehealth during this time and advertisements from startup companies ge...

Guest: Monica Maria Diaz, M.D., M.S. Climate change can have devastating effects on neurologic infections. One study suggested that the more population-dense urban areas are, the more likely several infections can be transmitted between humans. So what can be done to reduce this risk? Tune in with Dr. Monica Maria Diaz, Assistant Professor of Neurology at the University of North Carolina School of...

Guest: Erick Tarula, MD Many complications can occur in hospitalized neurologic al patients from an internal medicine standpoint. So a session from the 2024 Academy of American Neurology (AAN) Annual Meeting focused on these common issues , how they can be addressed quickly , and the role of a neurohospitalist. Dive in further with Dr. Erick Tarula, Assistant Professor in the Department of Neurolo...

Host: Eliza C. Miller, MD Stroke is one of the leading causes of death in pregnancy in the United States, underscoring the importance of knowing the causes, risks, and treatment of stroke in pregnancy and postpartum. That’s why Dr. Eliza Miller is here to share key insights from her session at the 2024 AAN Annual Meeting that focused on this exact topic. Dr. Miller is an Associate Professor of Neu...