Mayo Clinic Pharmacy Grand Rounds

Serena Mitaly, PharmD shares strategies for pharmacogenomic research translation to reduce health disparities. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at  https://ce.mayo.edu/  or on Twitter  @MayoMedEd . 

Devon Stonerock, PharmD, Uzo Abajue, PharmD and Divya Khandekar, PharmD describe cytokine release syndrome (CRS), the literature surrounding CRS and options for CRS management. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at  https://ce.mayo.edu/  or on Twitt...

Kelli Herrin, PharmD reviews the pathophysiology of transthyretin amyloidosis cardiomyopathy and provides updates on medication options.   For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at  https://ce.mayo.edu/  or on Twitter  @MayoMedEd . 

Jonathan Leung, PharmD, BCPS, BCPP provides updates on the clozapine REMS program, reviews the therapeutic benefits of clozapine, as well as key adverse events.   For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at  https://ce.mayo.edu/  or on Twitter  @MayoMedEd...

Sarah A. Chase, PharmD reviews the pathophysiology and current treatment strategies for inflammatory bowel disease, defines the clinical application of therapeutic drug monitoring of biologic therapies used in inflammatory bowel disease and discusses biologic therapy optimization based on therapeutic drug monitoring. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPh...

Kyle A. Hess, PharmD, BCPS Twitter: @KyleHessPharmD describes the pathophysiology of calcium channel blocker overdose, explains the rationale for use of insulin-euglycemic therapy in calcium channel blocker overdose and identifies differences between the pathophysiology of dihydropyridine overdose and non-dihydropyridine overdose. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Pr...

Scott A. Soefje, PharmD, MBA, BCOP, FCCP, FHOPA (Twitter: @sasoefje) describes the relationship between value and quality, defines quality and how quality measures will impact healthcare in the coming years, and demonstrates how organizations may use quality measures to improve value. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett E. S...

Benjamin J. Anderson, PharmD, MPH, FASHP and Diana J. Schreier, PharmD, MBA, BCPS recognize the history and regulations for prospective medication order review, describe the technical landscape for verification decision support and explore real-world verification decision support outcomes. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett...

Nikitha Yagnala, PharmD and Andy J. Jatis, PharmD, BCPS describe the pathophysiology of hepatorenal syndrome (HRS), describe the pathophysiology of hepatorenal syndrome (HRS) and outline an optimal patient care plan for the management of HRS. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett E. Schramm, Pharm. D.,  @garrett_schramm  on Tw...

Kamryn R. Storm, PharmD (Twitter @KRStorm ) outlines the mechanism of toxicity for ethylene glycol, identifies clinical findings of ethylene glycol toxicity and selects treatment regimens for suspected ethylene glycol toxicity. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett E. Schramm, Pharm. D.,  @garrett_schramm  on Twitter! You can...

Ashton C. Praska, PharmD (Twitter @ashpraka ) describes tetracycline resistance mechanisms utilized by bacteria, identifies how Omadacycline/Eravacycline can overcome common tetracycline resistance mechanisms and identifies clinical scenarios where Omadacycline/Eravacycline could be considered for use. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the...

Kristina M. Thurber, PharmD, BCPS recognizes pharmacotherapy for the treatment of obesity and explain mechanisms of action for each class, discusses and compares clinical data and weight loss outcomes for common treatment options, and determines an optimal pharmacologic regimen for the treatment of obesity given patient-specific factors. For more pharmacy content, follow Mayo Clinic Pharmacy Resid...

Jo Ann Leal, PharmD (Twitter @JoJoPharmD ) describes the key components of the drug supply chain and the impact of drug shortages, identifies common organizational strategies used to mitigate drug shortages and evaluates recent national efforts to stabilize the drug supply chain. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett E. Schram...

Andrew (Andy) F. Wiener, PharmD (Twtitter @andywiener ) describes the pathogenesis and risk factors of C. diff infection and recurrence, reviews the preferred treatment modalities for prevention of C. diff recurrence and describes the cost-benefit analysis supporting guideline-directed management of C. diff infections. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @Mayo...

Seth M. Kriha, PharmD identifies guideline recommended treatment to reduce LDL-C, evaluates landmark clinical trials for novel therapeutic agents indicated for treatment resistant hypercholesterolemia and develops a pharmacologic care plan for a patient with treatment resistant hypercholesterolemia. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the hos...

Christopher R. Cahoon, PharmD defines the importance of optimizing bone health in patients with bone metastases and lytic lesions, describes preferred bone-targeted therapy for patients with malignancy-associated bone disease and discusses the safety limitations associated with bisphosphonates and RANKL inhibitors. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPhar...

Shienna A. Braga, PharmD explains the effects of select chemotherapeutic agents on gonadal function and fertility in cancer patients, recognizes the different modalities utilized for fertility preservation in adults and children with cancer and reviews current literature that describes the role of gonadotropin-releasing hormone agonists (GnRHa) in women diagnosed with cancer. For more pharmacy con...

Linda Huang, Pharm. D identifies considerations for use of select provider-recommended supplements, describes literature that helps explain use of select supplements in outpatient treatment plans and discusses patient cases that highlight place in therapy for supplement use. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host, Garrett E. Schramm, Ph...

Ming May Zhang, PharmD (Twitter: @amayzhanggg ) reviews key bleeding and thromboembolic risks that should be considered in the perioperative setting, describes the current evidence for perioperative warfarin management in atrial fibrillation, venous thromboembolism, and mechanical heart valves and discusses patient- and disease-specific risk factors that may impact decisions regarding perioperativ...

Hailey A. Thompson, PharmD identifies the physiologic factors that increase venous thromboembolism risk in trauma patients, outlines current recommendations and their pitfalls for venous thromboembolism prophylaxis in trauma patients and discusses evidence for anti-Xa monitoring for venous thromboembolism prophylaxis with enoxaparin. For more pharmacy content, follow Mayo Clinic Pharmacy Residency...

Caitlin C. Schanz, PharmD ( @Schanz_Caitlin ) explains the pharmacological mechanism of steroid use in community-acquired pneumonia treatment, interprets literature assessing use of steroids in management of community-acquired pneumonia and relates efficacy and safety outcomes of steroids in community-acquired pneumonia to a patient case. For more pharmacy content, follow Mayo Clinic Pharmacy Resi...

Alejandro Del Rio Verduzco, PharmD (Twitter: @Alejandro_DRV ) defines the different short-term and long-term toxicities of CAR-T therapy, describes evidence for existing management strategies for late-term CAR-T toxicities and identifies evidence and reports of emerging late-term CAR-T toxicities. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes  or the host,...

Aleesha Jantzen, PharmD describes social determinants of health that impact management of cardiovascular disease states, recognizes racial/ethnic disparities in management of atrial fibrillation, myocardial infection, hypertension, and heart failure and identifies pharmacist interventions to minimize racial/ethnic disparities in cardiovascular disease state management. For more pharmacy content, f...

Tanner A. Melton, PharmD (Twitter @TAMeltonRx ) reviews factors associated with inter- and intra-patient mycophenolate pharmacokinetic variability, describes current strategies to perform mycophenolate therapeutic drug monitoring and determines an optimal monitoring plan for the treatment of a solid organ transplant recipient. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Progra...

Mark P. Layden, PharmD, MBA ( Twitter @Layden_Rx ) describes the pathophysiology of sepsis and role of Vitamin C in the critically ill population, identifies the proposed benefits of Vitamin C use in the critically ill patient population and discusses updated literature on the current role of Vitamin C in sepsis. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmR...