Lost Women of Science

Devastada por la muerte de su mentora, ocurrida tras un parto, Evangelina decidió dedicar su vida a la salud de la mujer. Tardó una década en reunir el dinero para ir a París, que en ese entonces era la meca de la formación médica. Nunca se rindió. A los 42 años se embarcó en un buque de vapor rumbo a Francia, país que experimentaba un boom durante los años de la posguerra. Estudió obstetricia y g...

A finales de la década de 1890, Andrea Evangelina Rodríguez Perozo era una de las tantas niñas pobres luchando por sobrevivir en la ciudad de San Pedro de Macorís, en la República Dominicana. Su vida dio un giro extraordinario cuando dos hermanos, poetas y escritores, llegaron de la capital. Notaron algo especial en la joven, quien vivía cerca. Con su ayuda, Evangelina fue a la escuela y, contra t...

In the late 1890s, Andrea Evangelina Rodríguez Perozo, known as Evangelina, was just another poor girl trying to survive in the provincial town of San Pedro de Macorís in the Dominican Republic. Her life took an extraordinary turn when two brothers, both poets and writers, arrived from the capital. They noticed something special about the young girl who lived nearby. With their help, Evangelina we...

En la década de 1880, una pequeña niña Afro-Dominicana pasaba sus días vendiendo dulces en las calles de San Pedro de Macorís, una bulliciosa ciudad portuaria en la República Dominicana. Abandonada por sus padres, quienes la tuvieron por fuera del matrimonio, su futuro parecía gris: en esta sociedad profundamente estratificada, pocas personas lograban escapar de la vida en la que habían nacido. Pe...

In the 1880s, a small Afro-Dominican girl spent her days selling sweets on the streets of San Pedro de Macorís, a bustling port town in the Dominican Republic. Born out of wedlock and abandoned by her parents, her horizons seemed narrow — in this deeply stratified society, few people ever broke free from the life they were born into. But Andrea Evangelina Rodríguez Perozo had something that made p...

Lisa See’s novel Lady Tan’s Circle of Women is inspired by a medical textbook published in 1511  by an eminent female doctor, Tan Yunxian. In this episode, we talk to See about the origin of her novel, and to Lorraine Wilcox, the scholar who translated the original Chinese text, about what the practice of medicine was like for a female doctor during the Ming Dynasty. Tan Yunxian was almost lost to...

In 1960 Marthe Gautier left the lab where she had discovered the genetic cause of Down syndrome, and went on to have a successful career as a pediatric cardiologist. For decades, she remained silent as her former colleague Jérôme Lejeune continued to take credit for this pioneering discovery, and history wrote her out of the story. Until 2009. On the 50th anniversary of the paper that announced th...

In the mid-1950s Marthe Gautier, a young French doctor and cytogenetics researcher, led a cutting-edge experiment to investigate the cause of Down syndrome. She painstakingly cultured cells in a ramshackle lab until one day she discovered an extra chromosome in the cells of patients with Down syndrome. This proved beyond a doubt that Down syndrome is genetic. In this first episode of our two-part...

In honor of International Holocaust Remembrance Day, we are telling the story of Margarethe Hilferding, a pioneering psychoanalyst and physician from Vienna who was murdered in a Nazi concentration camp in 1942. She was the first woman to earn a medical degree at the University of Vienna and the first woman to join Sigmund Freud’s Vienna Psychoanalytic Society. In her paper On the Basis of Mother...

Dr. Katalin Karikó, a Hungarian-born biochemist, dedicated her life’s work to messenger RNA, which she always believed had the potential to change the world. After decades of being ignored, she persisted with the research that eventually revolutionized the field of medicine and enabled the development of lifesaving vaccines in record time during the COVID-19 pandemic. Dr. Karikó tells her story in...

At this festive time of year, when many people are bringing trees into their homes to decorate for the holidays, we are going back to our story of a pioneering scientist who made it her mission to ensure that plants traveling across borders did not carry any diseases. It was in 1909, that the Mayor of Tokyo sent a gift of 2,000 prized cherry trees to Washington, D.C. But the iconic blossoms enjoye...

Two female botanists – Elzada Clover and Lois Jotter – made headlines for riding the rapids of the Colorado River in 1938 in an effort to document the Grand Canyon’s plant life. In Brave the Wild River: The Untold Story of Two Women Who Mapped the Botany of the Grand Canyon , author Melissa L. Sevigny retraces their journey and shows how the ambitious river expedition, one that many believed impos...

Carolyn Beatrice Parker came from a family of doctors and academics and worked during World War II as a physicist on the Dayton Project , a critical part of the Manhattan Project tasked with producing polonium. (Polonium is a radioactive metal that was used in the production of early nuclear weapons.) After the war, Parker continued her research and her studies at the Massachusetts Institute of Te...

Anna Von Mertens' thoughtful new exploration of Henrietta Swan Leavitt's life describes and illuminates Leavitt's decades-long study of stars, including the groundbreaking system she developed for measuring vast distances within our universe simply by looking at photographic plates. Leavitt studied hundreds of thousands of stars captured on the glass plates at the Harvard College Observatory, wher...

Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn’t work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research. But Dora Richardson, the chemist who had origi...

In the early 1960s, chemist Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen . Although her name is on the original patent, her contributions have been lost to history.  In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story. Lost Women of Science producer Marcy Thompson tracked down...

While researching her book about thalidomide in America, Jennifer Vanderbes discovered that there were far more survivors in the U.S. than originally thought – at least ten times more. These survivors were born with shortened limbs and other serious medical conditions after their mothers unwittingly took thalidomide in the early 1960s in so-called clinical trials. Wonder Drug  t ells the story of...

It’s September 2024 and a group of American thalidomide survivors arrive in Washington D.C. to lobby the government for support. More than 60 years have gone by since Frances Kelsey first stalled the New Drug Approval application from pharma company Merrell for thalidomide. Although she stopped the drug from going on the market in the U.S., hundreds of pregnant women still took thalidomide in Merr...

It’s the summer of 1962 and thalidomide has been off the market in Europe for months. But in the U.S., people are only just beginning to find out about the scandal. The Washington Post breaks the story and puts a picture of Frances Kelsey on the front page. She’s the hero who saved American lives. President John F. Kennedy gives her a medal and her image is splashed across newspapers around the co...

It’s 1961 and Widukind Lenz, a German pediatrician, is going door to door in his efforts to find out what is causing the epidemic of babies born with shortened limbs and other serious medical conditions. In the U.S., drug company Merrell is battling with Dr. Frances Kelsey at the Food and Drug Administration about the approval for thalidomide. She’s asking for data that shows it’s safe in pregnanc...

It’s the early 1960s and the German pharmaceutical market is booming. A sedative called Contergan is one of the bestselling drugs. Contergan’s active ingredient is thalidomide and it is touted as a wonder drug, a non-addictive sedative safer than barbiturates. In the U.S., the drug is called Kevadon, and its distributor is impatient to get the drug on the market. But Dr. Frances Kelsey, a medical...

In this first chapter of a new five-part season we meet Dr. Frances Oldham Kelsey, a physician and pharmacologist who joined the U.S. Food and Drug Administration as a medical reviewer in 1960. Before the year is out, Dr. Kelsey finds herself standing up to big pharma.  It’s September 1960 and a thick New Drug Application lands on Dr. Kelsey’s desk. The drug has already been on the market in Europ...

In the 1950s, a German drug company developed a new sedative that was supposed to be 100% safe: thalidomide. So safe, in fact, it was promoted to women as a treatment for morning sickness. It quickly became a bestseller. But in the early 1960s, shocking news started coming out of Europe. Thousands of babies were being born with shortened arms and legs, heart defects, and other serious problems. Ma...

In the 1920s, when newspapers and magazines started to showcase stories about science, many of the early science journalists were women, working alongside their male colleagues despite less pay and outright misogyny. They were often single or divorced and, as Marcel Chotkowski LaFollette explains, writing for their lives. From Emma Reh, who traveled to Mexico to get a divorce and ended up trekking...

By the second half of the 20th century, physicists were on a mission to find the ultimate building blocks of the universe . What you get when you zoom in all the way to the tiniest bits that can’t be broken down anymore. They had a kind of treasure map, a theory describing these building blocks and where we might find them. But to actually find them, physicists needed to recreate the blistering-ho...