Listen to The Lancet Neurology

Alison Rowan discusses epilepsy services in the UK, and a review about CADASIL.

Helen Frankish discusses research on childhood stroke, and add-on drug therapy for MS.

Elena Becker-Barroso discusses the ISAT study follow-up, and paracetamol use in acute stroke.

Helen Frankish discusses the global incidence of stroke, and a research article assessing the malaria drug quinacrine for the treatment of prion disease.

Helen Frankish discusses articles on stroke prevention after TIA, and the potential of stem-cell therapy for the treatment of multiple sclerosis.

Helen Frankish discusses antipsychotics and Alzheimer's disease, and desmoteplase for ischaemic stroke.

Helen Frankish discusses articles about galantamine for severe Alzheimer's disease, and a genome-wide association study about CJD.

Helen Frankish discusses articles on NMDA-receptor encephalitis, perilesional brain oedema, and looks ahead to the TLN stroke conference in Beijing.

In this month's Lancet Neurology Podcast, Editor Helen Frankish discusses two research articles: one on the treatment of hemicrania continua, and another on perception of pain in a minimally conscious state. Also discussed is a review on sudden unexpected death in epilepsy.

Helen Frankish discusses highlights from the October issue, including follow-up results for trials comparing carotid stenting with endarterectomy in patients with stenosis; and the PRoFESS study comparing drug combinations to reduce the severity of recurrent ischaemic stroke.

Elena Becker-Barroso discusses highlights from the September issue, including the potential of PB2 to slow the development of amyloid beta in patients with Alzheimer's, and how telemedicine could improve stroke treatment.

Helen Frankish discusses biomarkers for indications of dementia, and other highlights from the August issue.

The International LRRK2 Consortium, which includes investigators in 21 centres, has collected data from almost 20000 patients with Parkinson's disease carrying mutations in the LRRK2 gene. The Lancet Neurology editor Elena Becker-Barroso and Daniel Healy, the corresponding author on their first report, summarises the findings and their implications in clinical practice in a podcast.

Editor Helen Frankish discusses highlights from the June issue: a randomised trial showing the efficacy of a ketogenic diet to protect against childhood epilepsy; and a trial with phase II results for the Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease.

Editor Helen Frankish discusses highlights from the May issue: results from the INTERACT trial showing how intensive blood pressure lowering could be beneficial for people who have had intra cranial haemorrhage; also discussion of a genetic study identifying a gene mutation involved in amyloid lateral sclerosis, and a review of stroke in children.

Editor Helen Frankish discusses highlights from the April issue: including the EPITHET study of alteplase treatment 3-6 hours after a stroke, and donepezil treatment in patients with CADASIL, a genetic form of vascular dementia.

Editor Helen Frankish discusses highlights from the March issue: including research Articles about a genetic clue to the cause of dystonia, a neurological disorder relating to Parkinson's disease; and a study identifying older age (68 years) as a risk factor for stroke among people given stenting rather than Endarterectomy to unblock the carotid artery.

Imaging of amyloid β in Alzheimer's disease with a novel PET tracer Amyloid β (Aβ) deposits can be imaged by PET, but most Aβ PET ligands are not suitable for clinical diagnosis of Alzheimer's disease (AD). To test the effectiveness of a new Aβ PET ligand, 18F-BAY94-9172, Christopher Rowe and colleagues compared its binding with Aβ deposition in patients with...

Epilepsy in children encompasses several syndromes that have different prognoses but are all characterised by a predisposition to recurrent seizures; therefore, treatment has to be tailored to the individual. Any treatment regimen for children with epilepsies should have rational goals, take into account the additional morbidities that are commonly found in these patients.

Editor Helen Frankish discusses highlights from the December issue: original research investigating the efficacy of minocycline for the treatment of amyotrophic lateral sclerosis (ALS); a randomised trial assessing the effect and treatment duration of topiramate for the prevention of migraine; and a brief discussion of a review about medulloblastoma in children.

Editor Helen Frankish discusses highlights from the November issue: two Articles looking at the early treatment of minor strokes or transient ischaemic attacks and the risk of stroke, an Editorial calling for more funding for headache research, and a large multinational study identifying genetic variants that influence the development of epilepsy.

Editor Helen Frankish discusses this month's leading edge editorial: the unsuccessful appeal against the UK National Institute for Health and Clinical Excellence (NICE) after its recent decision to not make dementia therapies widely available in the UK on grounds of cost-effectiveness

Editor Helen Frankish discusses highlights from the September issue: an association between Epstein-Barr virus and acquisition of multiple sclerosis in children; and current opportunities for the development of anti-epileptic drugs. Epilepsy and HIV are also discussed in this month's leading edge editorial.

Editor Helen Frankish discusses two topics from the August issue: a research article suggesting people with epilepsy are three times more likely than the general population to commit suicide; and she interviews the author of a position paper about a new research framework for the diagnosis of Alzheimer's disease.

In this month's Lancet Neurology podcast Helen Frankish discusses a research article concerning numerous factors which determine the risk of recurrent venous thromboembolism after cerebral venous thromboembolism in children. Also discussed is the Leading Edge editorial calling for a more modern approach to stroke services in the UK, and the review about silent infarcts, which could be a useful...