Listen In - Bitesize Bio Webinar Audios

The best way to solve a problem is to avoid it in the first place. While journals can and do reject articles for scientific reasons, they also reject articles for structural issues. By taking a few simple steps, you can learn how to circumvent these difficulties for a smooth publication process. In this episode of Listen In , we'll go through some of the structural reasons that scientific journals...

All research papers have certain elements in common: Introduction, Methods, Results, and Conclusion. How can you structure your introduction to best frame the research question for your readers? Must the methods section read like a laundry list of reagents? Can you be dramatic in the results without losing objectivity? Is there any room in the concluding section to pose new conflicts? In this epis...

Rarely do we consider writing a scientific paper as a creative exercise. But what if that could change? The best way to communicate anything is through stories. The scientific process has all the elements inherent in storytelling: a rich background, a problem or conflict to solve, and a resolution. In this episode of Listen In , we will reframe the writing process to help you clearly and concisely...

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In , discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases. Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin ge...

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission at the ultrastructural level. Neurons communicate at specialized junctions, or synapses, via chemical messengers called neurotransmitters. Within a millisecond of neuronal stimulation, synaptic vesicles packed with neurotransmitters...

Experience the transformative power of unbiased, data-driven cell analysis with access to over 25 image-derived label-free parameters, empowering you to easily assess sample quality, optimize gating strategies, and validate rare events. In this episode, learn how automated image analysis combined with flow cytometry can help improve data accuracy and precision, optimize and verify gating strategie...

Organoids are three-dimensional in vitro cultures derived directly from patient tissues or induced pluripotent stem cells (iPSC) and embryonic stem cells. They self-organize to generate structures that resemble the tissue of origin and recapitulate the key physiological functions of the parental organ. In this episode of Listen In , explore the benefits of organoids as infectious disease models an...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community.  This episode of Listen In with Cristy Gelling explores image manipulation. Many common types of image manipulation are classif...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community.  This episode of Listen In with Karen O'Hanlon Cohrt explores publishing negative results and what is acceptable. Get answers t...

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the boundary of what is acceptable and slip into habits that are unacceptable within the scientific community. This episode of Listen In with Karen O'Hanlon Cohrt defines plagiarism and presents some relevant statistics on this topic. She...

Eukaryotic cell cultures respond to the slightest influence. Apart from the risk of contamination, minimal changes in cultivation parameters can affect their viability, growth, and cell metabolism. In this episode of Listen In , discover the measures you can take to improve the reproducibility of your experiments by incorporating Good Cell Culture Practice into your eukaryote culture routine. Expl...

Many scientists see the added value in using electronic pipettes and have already upgraded their pipette fleet. The benefits include: • Reduced strain on thumbs and arms by improving pipetting ergonomics. • Increased reproducibility of experiments with motor-operated pipetting cycles. • Easy and efficient handling of high sample throughput. In this episode of Listen In , learn why switching to ele...

Next-generation sequencing (NGS) has revolutionized the ‘omics’ era, with the rapid decoding of massive DNA sequences, supporting the investigation into various biological processes in human disease, genetic inheritance, immunity, cancer, and others. But generating high-quality NGS libraries is a labor-intensive process that requires experience, precision, and accuracy. Optimal, thorough sample pr...

Centrifugation is the cornerstone of lab life, used in nearly every workflow, be it a routine task like pelleting cells or a dedicated assay for an important biomolecular target. That's why it's such a pain when they break down. But just because we use centrifuges every day doesn't mean there aren't important technical aspects to consider or no parameters you can tailor to your specific applicatio...

Some scientific papers are unbelievable as they showcase experimental excellence that we did not think possible. These papers astound us with their groundbreaking findings and meticulous methodologies. However, alongside these unbelievably good papers, there are papers that are unbelievable due to the pervasive presence of statistical mistakes that undermine their credibility. Whether due to negli...

Your ultra-low temperature (ULT) freezer is not just a storage room for samples; it is your assurance for long-term scientific success and guards the results of your work. Therefore, every researcher should understand the importance of ULT freezers, know how to choose a reliable one, understand best practices for sample management, and have clear guidance on maintaining ULT freezers. In this episo...

Have you ever transferred glycerol or ethanol with a pipette? We all know how hard it is, and we've all been dubious about the accuracy of our final volumes. While you probably realize that your liquid type and pipetting technique can influence your analysis results, you might be less sure about what pipettes to use when your assays involve challenging liquids and ultra-repetitive steps. In this e...

Intravital imaging of cellular dynamics in a natural physiological microenvironment can provide unprecedented insights into the dynamic pathophysiology of diseases. In this episode of Listen In , get a demonstration of the latest technology to image inside the cells of live animals. Watch real-time multicolor sub-micron resolution image acquisition for dynamic cellular events, such as gene express...

What are the motives behind science misconduct? How is data manipulated to evidence dubious results? And do you think you can spot edited and faked data? Any fraud in science is too much, but the reasons for it are complex. In this episode of Listen In , join forensics detective Elisabeth Bik and explore the answers to these questions. See the work she has done uncovering scientific misconduct, an...

What's more disappointing than running your flow cytometry sample to discover it's rubbish? Especially considering time on cytometers can be precious, even more so if you've booked onto an in-demand one at a busy core facility. You've done all the work and all the waiting—for nothing. If this scenario sounds familiar, this episode of Listen In is for you. Jessica Rowley, Flow Cytometry Facility Ma...

Scientific writing is an art that requires as much attention and proficiency as your hands-on lab work. When done right, it can significantly contribute to your scientific endeavors. But, if not taken seriously, inconsistent language, formatting, and terminology can hinder your work's clarity and distract from your remarkable scientific findings. In this episode of Listen In , our Content Creation...

Are you an early career scientist looking for guidance on your career path? Or you're a seasoned researcher considering a career change and want to know what's out there. We've brought together a panel of experts and bioscientists with a wide range of experience to share their insights and help you carve out the best career possible. Get advice and tools to forge a path that suits you—inside or ou...

Freeze fracture is a powerful technique that enables imaging of internal structures of cells and tissues at the nanoscale level by freezing samples at ultra-low temperatures and then fracturing them along natural weak points. These structures can be imaged without dehydration or distortion using cryo-SEM, providing high-resolution images with great clarity. Discover how to use freeze fracture and...

As a researcher, one of the most crucial skills to develop is the ability to perform a thorough review of manuscripts. Manuscript reviewing is a vital job that requires specific skills and knowledge to properly assess published literature. By reading and reviewing papers, researchers can develop and hone these skills, which will help them identify and handle tricky issues such as image and data ma...

Have you ever wondered what other jobs are ideal matches for your analytic and artistic skills? Are you looking for an exciting new career in marketing, or have you ever wondered if it was for you? In this episode of Listen In , discover how the assets that make you a great scientist could also make you a great marketer in today's data-driven markets. Learn the role of a marketer, how scientific s...