Global Dispatches -- World News That Matters

As I am recording this on Friday, April 10, JD Vance is en route to Islamabad, Pakistan, for negotiations over a ceasefire announced on April 7. This ceasefire is shaky at best. It is clear that there was never a common understanding between Iran and the United States about what might be included in a ceasefire, but American and Iranian delegations are headed to Islamabad to discuss these details....

Pandemic Risk Assessment is an emerging scientific toolkit designed to assess how pandemic risk is evolving over time. Rather than predicting the next outbreak, it integrates evidence across scientific disciplines to identify the drivers and estimate the probabilities of pandemic outbreaks. And in so doing, it can help policymakers prioritize prevention and preparedness investments before crises e...

Many of our best surveillance tools today that were originally built to target specific diseases like polio and malaria have become critical infrastructure for outbreak response and early warning across a wide range of pathogens. This includes laboratory networks, diagnostic tools, and community health workers—all of which play vital roles in broader outbreak preparedness. In today's episode, two...

Robust disease surveillance systems are the foundation of strong public health systems and are essential to preventing, detecting, and responding to health threats before they escalate. Commitments to and investments in quality disease surveillance systems are key to smart, cost-effective public health decision-making, which is needed more than ever. Before the Outbreak is a three-part podcast ser...

Today's episode is produced in partnership with the Global Challenges Foundation. The foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. The Global Challenges Foundation's 2026 Global Catastrophic Risks report outlines five of the biggest risks facing humanity today, including weapons of mass destruction, the topic of this...

One year ago, in 2025, former Philippine President Rodrigo Duterte was extradited to The Hague to face charges of crimes against humanity and murder for orchestrating a campaign of extrajudicial killings against people he deemed to be involved in the drug trade. Over the course of several years while he was president, thousands of people were killed by police and hit squads. Now, he faces justice...

For the first time in nearly 70 years, it looks like there may be major political changes afoot in Cuba — driven by the United States. The Trump administration has been ratcheting up pressure on the island, including by imposing an oil embargo that is strangling the country's energy supplies. On Monday, March 16, Cuba experienced a complete collapse of its electric grid, triggering a nationwide bl...

Earlier last last week, he United Nations reported that around 300,000 Lebanese had been displaced since Israel opened a new front in southern Lebanon amid this widening regional conflict. Yesterday, that figure surged to more than 800,000 people forced from their homes in just a matter of days. Lebanon is where the humanitarian crisis stemming from the Iran war is most urgent at the moment—but th...

Today's episode is produced in partnership with the Global Challenges Foundation. The Foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. Global Challenges Foundation's 2026 Global Catastrophic Risks report outlines five of the biggest risks facing humanity today, including catastrophic climate change, the topic of this epi...

We cover a lot of ground in  this week's episode of  To Save Us From Hell !  There are two new entrants to the race to succeed António Guterres as the next UN Secretary-General; Cindy McCain announced she is stepping down as head of the World Food Programme, meaning there will soon be a vacancy at the top of one of the largest UN agencies—one typically led by an American; and we dissect a bizarre...

Things are obviously moving very fast in the Middle East. When I caught up with my guest today, Dalia Dassa Kaye, the war was in its second day. Bombings in Iran and throughout the region continued at a rapid clip, and there was little sense of when, if, or how it might end. Regular listeners of the show are no doubt familiar with Dalia Dassa Kaye. She is a senior fellow at the UCLA Burkle Center...

Earlier this week, Defense Secretary Pete Hegseth held a high-stakes meeting with Anthropic CEO Dario Amodei and, according to several news reports, delivered an ultimatum: either Anthropic drops the safety guardrails built into its AI model, Claude, or it faces potentially punishing consequences—including invoking the Defense Production Act to effectively seize Claude, or banning Anthropic outrig...

Ethiopia is on the brink of a war that could turn into a major regional conflagration. Over the past several weeks, military forces have been moving into position across the region in a conflict that would pit the government of Ethiopia and some allied militias against Eritrea and a rebel faction from Ethiopia's northern Tigray region, among others. There are several concurrent forces driving the...

It was an odd juxtaposition: Trump's inaugural Board of Peace gathered in Washington, D.C. as the U.S. appeared to be readying for war with Iran. In this week's  To Save Us From Hell episode, Mark and Anjali discuss why this Board of Peace can't really compete with the Security Council, and what its advent says about international relations today. They then discuss a looming American attack on Ira...

On February 3, the United States deployed a warship and Coast Guard vessels off the coast of Haiti, near Port-au-Prince. The move came amid political wrangling within Haiti's Transitional Presidential Council, as some members sought to block Washington's preferred candidate from becoming the next prime minister. This deployment comes amid a deepening political, security, and humanitarian crisis in...

The New START treaty, signed by the United States and Russia in 2010, limited both countries to 1,550 deployed strategic warheads, placed restrictions on how those weapons could be deployed, and included strong verification mechanisms to ensure compliance. On February 6, 2026, that treaty formally expired. And now, for the first time in decades, there is no bilateral nuclear arms agreement between...

Donald Trump doesn't much like Pedro Sánchez — and the Spanish prime minister is perfectly fine with that. Unlike other European leaders who reflexively genuflect to the American president, Pedro Sánchez stands apart for his willingness to confront Trump—not for its own sake, but in service of a theory of politics that diverges sharply from many of his European counterparts. As my guest, journalis...

For the first time in history, multiple countries have jointly nominated a candidate for UN Secretary General. Earlier this week, Brazil, Chile, and Mexico endorsed Michelle Bachelet—a former president of Chile, former UN High Commissioner for Human Rights, and a survivor of brutal repression under the Pinochet regime. The move is unprecedented—and potentially transformative. What does it signal a...

The Chicago Council on Global Affairs has been tracking American views on foreign policy since the end of the Vietnam War. Last week, it released its  2025 survey —and the results point to a widening partisan divide on some of the most fundamental questions about America's role in the world. That was not always the case. For most of the past 50 years, Democrats, Republicans, and independents large...

For the past year and a half, South Sudan has been on the brink of a new civil war. A 2018 peace deal that ended the last civil war has been faltering, while the war across the border in Sudan has threatened to spill south. According to my interview guest, Daniel Akech of the International Crisis Group, the tipping point has been breached. We are now in the early stages of a new civil war in South...

One year ago, the United States was winning the global fight against HIV/AIDS. Thanks largely to American leadership, infections and deaths from HIV/AIDS have dropped precipitously over the past 20 years, ever since the U.S. government made combating the disease a global priority. Some once–hard-hit countries in sub-Saharan Africa were even on track to become AIDS-free by 2030. But then, suddenly...

Can Donald Trump's new Board of Peace really compete with the Security Council? Will we even be discussing it a week or two from now, or will Trump and other world leaders simply move on? And what's with the Board's logo, which looks almost like a parody of the United Nations emblem? Mark and Anjali break down the newest—and perhaps strangest—entrant into the multilateral peace and security space,...

Protests sweeping Iran are unlike anything the regime has faced since coming to power in 1979. What began as demonstrations by shopkeepers in Tehran over the sharply devalued Iranian rial quickly morphed into sustained, nationwide anti-government protests. The government responded with extreme brutality, killing thousands of people—and in doing so, once again put itself in the crosshairs of the Un...

On Christmas Day, the United States launched a series of missile strikes in Nigeria, ostensibly against jihadist groups. In the weeks prior, Donald Trump had been claiming that Christians in Nigeria were being subjected to systematic attacks by such groups, and he framed these strikes as a "Christmas present" that killed jihadist leaders and destroyed terrorist camps. But that does not seem to hav...

Danes are reeling from the aggressive nature of Donald Trump's designs on Greenland — but there is little they can do to stop the United States from acquiring the territory, whether by force or coercion. This is an odd position for Denmark, which has long been one of America's staunchest allies, as well as a core member of the European Union and NATO. My interview guest, Søren Lippert, is the CEO...