Genetics (Audio)

Don Cleveland, PhD, shares new research on the role of chromothripsis, targeting cancers driven by ecDNA and more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37586]

Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]

There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]

Jonathan Sebat, PhD shares current research on how combinations of rare gene mutations and complex common variant risk factors contribute to autism. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 37658]

To Sheng-Ying Pao, the power of reframing CRISPR lies in what is absolutely ordinary: paper. In CRISPaper, Pao revisited a cultural past in the ancient art of papermaking. In ancient China, wild rice was used to make paper. Pao took rice stalks from plants edited with CRISPR and ground the fibers into pulp. She then poured the pulp over a mesh screen. Every time she dipped the screen into water, t...

UC Consortium launches first clinical trial using CRISPR to correct the gene defect that causes Sickle Cell Disease. Dr. Mark Walters of UCSF talks about a new CRISPR gene therapy developed by scientists and physicians at UC Berkeley, UCSF and UCLA. The trial aims to directly correct the sickle mutation in blood stem cells that causes them to create deformed red blood cells, leading to the debilit...

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Herman Pontzer explores the evolution of metabolism, Grazyna Jasienska discusses different effects of activity on women's reprod...

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Jandy Hanna explores climbing in human evolution. Most primates live and move in the trees, but humans have evolved to move bipe...

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Herman Pontzer explores the evolution of human metabolism and its role in our evolution and health. From an evolutionary perspec...

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Ellen Breen explores an evolutionary pathway for high endurance activity. Series: "CARTA - Center for Academic Research and Trai...

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Yana Kamberov explores how sweating evolved and what it means for Homo sapiens. Humans use sweating as the primary mechanism to...

Explores cellular anthropology to understand how variation in human regulatory elements can mediate morphological evolution and individual variation of the craniofacial form. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 32973]

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Tatum Simonson explains adaptations to altitude and diving. Humans have persisted for hundreds of generations under challenging...

Breakthroughs in genomics and targeted therapies are revolutionizing the practice of clinical oncology. Precision genomics and immunotherapy offer promise to improve outcomes in cancer, but doing so means we need to move beyond historical models for cancer diagnosis and treatment. Razelle Kurzrock, MD discusses insights from this rapidly changing field and addresses some of the ethical challenges...

Mark Tuszynski, MD, Ph. D., Bob Yant, and Lawrence S.B. Goldstein, Ph. D. discuss the newest research and treatments for spinal cord injury, including how neural stem cells may be leveraged to potentially regain function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37102]

Experts address altered states of the mind that are deliberately induced by humans. We will address what is known about origins and mechanisms of these mind-altering practices. In doing so, we hope to gain new insights into the origins and workings of the human mind. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 36671]

Stem cells may play a critical role in treating genetic diseases. Hear from experts in the field. Moderated by Matthew Porteus, MD, PhD, Stanford University Tippi MacKenzie, MD, UC San Francisco: Fetal Therapy for Alpha Thalassemia Major Matthew A. Spear, MD, Poseida Therapeutics: CAR-T Cells: Poseida Therapeutics Stephen Gottschalk, MD, St. Jude Children's Research Hospital: Gene Therapy for X-li...

Stephen Gottschalk, MD St. Jude Children's Research Hospital Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36350]

Rosa Bacchetta, MD Stanford University Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36345]

What impacts has stem cell research made for blood and immune system disorders? Hear the latest from experts in the field. Moderated by Crystal Mackall, MD, Stanford University Alysia Vaccaro: Patient Perspective Jennifer M Puck, MD, UC San Francisco: Gene Therapy for Artemis Severe Combined Immunodeficiency (ART-SCID) Donald B. Kohn, MD, UCLA: Hematopoietic Stem Cell Gene Therapy for Primary Immu...

Donald B. Kohn, MD UCLA Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36330]

Jennifer M Puck, MD UC San Francisco Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36329]

Mark C. Walters, MD UCSF Benioff Children's Hospital Oakland Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36331]

Matthew A. Spear, MD Poseida Therapeutics Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36349]

Tippi MacKenzie, MD UC San Francisco Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36348]