Forum

Karl Deisseroth and Viviana Gradinaru speak with senior editor Markus Elsner about the current state of optogenetics and how it can be used to better understand and treat human disease.  Hosted on Acast. See acast.com/privacy for more information.

Lillian Siu and Elaine Mardis speak with senior editor Markus Elsner about the current state of precision cancer medicine and what progress the future might hold. Hosted on Acast. See acast.com/privacy for more information.

Nature Biotechnology ’s Irene Jarchum speaks with Michel Sadelain about off-the-shelf CAR-T cells, and discusses a recent paper from Maksim Mamonkin’s group describing a clever strategy to mitigate CAR-T cell rejection. The paper was published in Nature Biotechnology and can be read here . Hosted on Acast. See acast.com/privacy for more information.

David Liu and Jennifer Doudna talk with our Senior Editor Markus Elsner about the state of the genome editing field and what challenges remain, especially as various therapies are now entering the clinic. This episode is part of Nature Biotechnology ’s Focus issue on CRISPR tools and therapies. Hosted on Acast. See acast.com/privacy for more information.

A recent Nature Biotechnology paper from Tony Atala and colleagues at Wake Forest describes the use of bioengineered scaffolds to repair substantial injuries to rabbit uteri, supporting pregnancies and live births. Senior Editor Irene Jarchum discusses this work with Mats Brännström and Mats Hellström, both from Gothenburg University in Sweden. You can read the paper here .  Hosted on Acast....

David Shapiro Ilan talks to Senior Editor Susan Jones about a paper in the May issue where Ricardo Machado and colleagues describe how bacterial symbionts of nematodes are evolved to help these worms kill a devastating crop pest: Western Corn Rootworm. The paper can be read here . Hosted on Acast. See acast.com/privacy for more information.

Senior Editor Markus Elsner talks to Alex Marson of UCSF about the significance of a Science paper describing the phase 1 clinical trial of CRISPR-engineered T cells. The work was carried out by Carl June and Edward Stadtmauer from UPenn. Read the paper here . Hosted on Acast. See acast.com/privacy for more information.

Senior editor Irene Jarchum talks to Cliona Rooney about a recent paper in which Mark Cobbold and colleagues describe an antibody-mediated strategy to re-target virus-specific T cells against tumors. The paper was published in  Nature Biotechnology; it can be read  here . Hosted on Acast. See acast.com/privacy for more information.

Brady Huggett talks with Zemin Zhang about a recent  Nature Biotechnology  paper detailing the use of spatial transcriptomics in providing new insights into tumor architecture. The work was done by Itai Yanai and co-authors, and the paper can be read  here .   Hosted on Acast. See acast.com/privacy for more information.

Senior Editor Irene Jarchum talks to Stefan Schneeberger about the significance of a recent Nature Biotechnology paper describing a sophisticated perfusion machine to keep human livers alive for a week. The work was carried out by Pierre-Alain Clavien and colleagues from ETH Zurich. Read the paper here . Hosted on Acast. See acast.com/privacy for more information.