#ExpertAnswers - an InsideScientific Podcast

Marshall McCue discusses case studies using small mammals where 13C-labeled nutrient oxidation is tracked second-by-second in real-time using laser-based stable isotope approaches.

This episode of #ExpertAnswers features Professor Lora Heisler, Chair in human nutrition at the University of Aberdeen, who recently joined us for a webinar on the brain circuits driving appetite. Professor Heisler was awarded the 2018 Outstanding Scientific Achievement Award from the American Diabetes Association for her research identifying a new type of medication to improve diabetes and obesit...

In this episode of Expert Answers, Chris Adams and Jennifer Petrosino discuss VO2Max test optimization for cardiometabolic phenotyping in rodents.

John Hasenau and Stefano Gaburro answer questions from a webinar where they discuss current biosafety requirements and what home cage monitoring can teach us in bioexclusion and biocontainment studies.

DeWayne Townsend and Adam Goodwill discuss the fundamentals of pressure-volume loop analysis as a means to study cardiac function.

Miroslaw Janowski and Piotr Walczak discuss how PET/CT imaging can be used to enable image-guided neurointerventions and to study targeted delivery and clearance of therapeutic agents.

In this episode of Expert Answers, Drs. Subramanian & Enzmann share case studies and experimental data from various applications using a newly developed automated system to measure vision based on the optomotor reflex.

Tonya Coulthard discusses the features and benefits of SuperArgus PET/CT systems and reviews its unique capabilities.

In this episode of Expert Answers join Dr. Tim West and Matt Borkowski for a discussion on how to properly isolate and prepare, and assess muscle performance and contractile function in single muscle fibers.

Robert Gould and Michael Girand discuss methods and applications for the use of EEG as a biomarker for sleep, substance use disorder and CNS disorders.

In this episode of Expert Answers, John Cirrito and Candace Rhode-Johnson discuss the use of a novel movement responsive rodent caging system.

Konrad Juczewski and Mary Ann Go discuss 2-photon imaging of hippocampal place cells and on stress monitoring in head-fixed, awake and behaving mice.

Ralph Lydic and Tally Largent-Milnes discuss physiological mechanisms behind the opioid epidemic and present their research on the effects of opioids on sleep and respiratory depression in preclinical mouse models.

Melanie White discusses basic isolated Langendorff heart principles, key experimental design considerations, core technology requirements and best practice tips to support consistency and validation of your research.

Five experts from the University of Bristol, the German Center for Neurodegenerative Diseases, and the Hungarian Academy of Sciences answer questions from a webinar where they present methodology and research findings from neurophysiological studies in head-fixed, behaving mice.

Marcio Furtado discusses the importance of anomalous EEG detection to study experimental epilepsy, why continuous EEG monitoring at a high sampling rate is critical to properly detect seizures, and how to effectively deal with large telemetry data sets.

Dr. Tim Hacker discusses experimental design, strategy, technology, common challenges and best-practices associated with planning long-term, chronic models of cardiovascular disease in rodents.

Ronglih Liao and Davor Pavlovic discusses techniques for isolating cardiomyocytes using both traditional and Langendorff-free methodologies, including key considerations, best practices and how to achieve and confirm optimal myocyte quality.

Dr. Keshari Thakali from the University of Arkansas for Medical Sciences and Aaron Stupica from DMT answer questions from a webinar discussing techniques and best practices for tissue bath myography and present a unique case study looking at the effect of maternal obesity on offspring perivascular adipose tissue and vascular function. For more information or to watch the webinar, click here.

Brandon Bucher answers questions from a webinar sharing best practices, technical considerations and expert advice on how to avoid common data acquisition system and data analysis mistakes in order to produce higher quality data.

Stephanie Simonds and Megan Fine present wireless glucose monitoring methodology, best practices, research findings, and discuss the power of continuous glucose profiles, particularly when combined with other gold standard assays to study obesity, diabetes and cardiovascular related diseases.

Clive May and Yugeesh Lankadeva present groundbreaking research in models of Acute Kidney Injury, and the methods used to gather these insights using the latest in fibre optic sensing technology to obtain dissolved oxygen and microvascular blood perfusion at the tissue level.

In this episode of Expert Answers, Carlos Del Rio, PhD and Megan Fine, DVM discuss a novel method of recording serial measurements of cardiac function in rodents.

In this episode of Expert Answers, Dr. Jay W. Mason and Mike Gralinski review advances in ECG safety assessment.

In this episode of Expert Answers, listen as Téa Tsaava, PhD, Chris Langdale, & Martin Schüttler, PhD discuss the technological background of nerve cuff electrodes.