EuFMD

We earlier isolated 10 single-domain antibodies (VHHs) that specifically bind intact (146S) FMDV particles but not the (12S) degradation products of serotype A strain A/TUR/14/98. Such 12S particles are much less immunogenic than 146S particles. As a result, the 146S particle specific VHHs are useful tools for quality control of FMDV antigens used in vaccines. Conventional monoclonal antibodies (m...

Lumpy skin disease (LSD) is a WOAH notifiable transboundary cattle disease caused by lumpy skin disease virus (LSDV), a dsDNA virus member of the Capripoxvirus genus, belonging to the Poxviridae family. LSD primarily affects cattle, causing fever, enlarged lymph nodes, lesions of the oral mucous membranes, of the respiratory, and digestive tract, abortions and a reduction in milk production. Consi...

Lumpy skin disease (LSD) is a WOAH notifiable transboundary cattle disease caused by lumpy skin disease virus (LSDV), a dsDNA virus member of the Capripoxvirus genus, belonging to the Poxviridae family. LSD primarily affects cattle, causing fever, enlarged lymph nodes, lesions of the oral mucous membranes, of the respiratory, and digestive tract, abortions and a reduction in milk production. Consi...

Virus Neutralization Test (VNT) and Solid Phase Competitive ELISA (SPCE) are useful tools for a wide range of in vitro investigations, focused on serology studies in livestock and wild animals. After vaccination campaigns or immunogenicity studies, related to the control of Foot-and-mouth Disease (FMD), VNT and SPCE are usually performed to detect immune response of animals and, subsequently, the...

Foot-and-mouth disease (FMD) is a highly important disease of domestic and wild cloven-hoofed animals caused by the foot-and-mouth disease virus (FMDV). Among FMDV serotypes, serotype O and A are the most widely distributed serotypes in Asia and serotype Asia 1 occurs only in Asia. Rapid and accurate detection and serotyping of foot-and-mouth disease virus (FMDV) is essential for implementing cont...

Peste des Petits Ruminants and Rift Valley Fever events 2020-2022 - V. Chevalier by European Commission for the Control of FMD

Livestock diseases have gender implications. Female livestock keepers who make up 60% of the world's poor livestock keepers (World Bank et al. 2009), can be particularly affected and are therefore an important target group for last-mile animal health services. In low-to-middle-income countries (LMICs), veterinary paraprofessionals (VPPs) play an important role for smallholder farmers (SHF) who oft...

An Augmented Reality (AR) tool for mobile devices and the Hololens AR headset has been designed to help educate farmers, stock agents and students to identify key signs of some of the most important emergency animal disease (EAD) threats to the Australian sheep industry - foot & mouth disease, bluetongue, scrapie and sheepox. The tool allows them to scan a room, paddock or any other space and plac...

A competency-based approach able to incorporate the knowledge produced by the World Organisation for Animal Health (WOAH), is the basis of its new Training System. Organised around sixteen competency packages (CPs), the system aims at developing capacities in WOAH Members to facilitate the implementation of the international standards and guidelines and to strengthen Veterinary Services resilience...

Understanding the level of preparedness to use emergency vaccination for FAST diseases in European countries by Kathy Gibson EuFMD is conducting a program of work to better understand the role of emergency vaccination for Foot and Mouth Disease (FMD) and similar Transboundary Animal Diseases (FAST) in Europe and its neighbourhood. Materials and Methods In 2022, EuFMD hosted two online workshops wi...

As Denmark has not had an foot and mouth disease (FMD)-outbreak since 1983, the objective of this study was to use epidemiological modelling to compare the effects of a set of different mitigation measures on e.g. predicted number of infected and culled herds, and epidemic control duration1. The epidemiological impact of basic mitigation measures was compared to additional mitigation strategies on...

The aim of our research was to learn and discuss the personal experiences of Canadian emergency management professionals working in a VEOC environment during the COVID-19. The main research questions were: 1. What are emergency management professionals’ personal experiences of working in a VEOC environment during the COVID-19 pandemic response? 2. What are the benefits and challenges emergency man...

Application of trading zones when managing livestock disease outbreaks has the potential to markedly reduce the economic impact of trade restrictions placed on countries. This involves establishing areas within a country, which are considered of negligible risk of transmitting disease through livestock and livestock product shipments to other areas of the country or internationally. The objective...

A response system including outbreak investigation, emergency control measures, and risk assessment in the event of transboundary animal diseases such as foot-and-mouth disease (FMD), African swine fever (ASF), and highly pathogenic avian influenza (HPAI) in Korea, is describe in this presentation.

Headline FMD events 2020-2022 - D. King by European Commission for the Control of FMD

There are seven antigenically distinct FMDV serotypes; O, A, C, Asia1, SAT1, SAT2 & SAT3, with no cross protection between serotypes. There are five known antigenic sites on the FMDV capsid against which neutralizing antibodies bind to confer protection against the viral infection. VP1 contains the virus attachment motif (RGD) on the G-H loop that binds to the cellular receptor integrin for all th...

Peste des petits ruminants (PPR) and Rift Valley Fever are examples of transboundary animal diseases having major consequences in terms of health and economics. PPR is a highly pathogenic viral disease infecting principally sheep and goats, but also some wild artiodactyls, camelids and suids. This disease circulates in large parts of Africa, Asia, Eurasia and Middle-East and it has recently appear...

Foot -and- mouth disease (FMD) is an acute, highly contagious disease of cloven-hoofed animals with impacts on farming and is responsible for major economic losses. Serological assays that measure FMDV-specific antibodies are used to monitor the presence of FMDV, for checking quality of FMD vaccine and levels of post-vaccination immunity. The aim of this work was to develop a multiplex immunoassay...

The benefits of complete genome sequencing have become increasingly clear, for example the identification of emergent lineages with altered phenotypic characteristics or the fine scale tracking of virus movements. Indeed, in the UK in 2007 complete genome sequencing enabled the tracing of an outbreak of foot-and-mouth disease virus (FMDV), in turn allowing the identification of a missing premises....

Member Nations and relevant stakeholders have asked EuFMD to provide an efficient solution to enable National Veterinary services to map the progression of the individual skills, monitor the development of capacity and incentivize veterinarians’ education. TOM aims to support National Veterinary authorities to develop capacity development, identifying the gaps in specific competencies and how to f...

Post-vaccination serological monitoring is an important method for control of foot-and-mouth disease (FMD). In particular, a liquid-phase blocking enzyme-linked immunosorbent assay (LPBE) is more accessible than the virus neutralization test (VNT) for a large-scale serological screening. A FMD A/ASIA/Sea-97-G1 sublineage virus occurred and was named A/Pocheon/SKR/2010 (A/Pocheon) in 2010 in Korea....

1st isolation, molecular detection and phylogenetic analysis of FMDV A/AFRICA/G1, Sultanate of Oman by European Commission for the Control of FMD

In a sector that continues to witness increasing levels of risks that could disrupt our agricultural system, communities and economy, it is critical that we explore alternative means to preparing for and responding to emergencies. One such example has been the use of a virtual control centre (VCC) which has been considered here through a national (Exercise Network) and a state-based (QDAF VCC exer...

Post vaccination monitoring is essential to assess the effectiveness of vaccination campaigns against foot-and-mouth disease (FMD). There are several methods to screen FMD virus structural protein antibodies including Solid-phase competitive ELISA (SPCE), Liquid-phase blocking ELISA (LPBE) and Virus neutralization test (VNT). Among these, SPCE is widely used since VNT (gold standard test) has prac...

Abattoir activities are key components of veterinary training, however, accessing facilities can be difficult. The digital abattoir (DA) is a novel teaching tool that combines the advantages of blended learning and Virtual Reality to replicate and complement abattoir visits. The Digital Abattoir (DA) portrays five commercial establishments, including read and white meat species, delivering the con...