Decera Clinical Education Oncology Podcast

In this episode, Jubilee Brown, MD, and Elisabeth Diver, MD, provide expert insights on new data presented at ASCO 2022 for ovarian, endometrial, and cervical cancers regarding: Subgroup analyses from KEYNOTE-826 evaluating pembrolizumab in combination with chemotherapy with or without bevacizumab in persistent, recurrent, or metastatic cervical cancer Preliminary subgroup analyses from phase III...

In this episode, David Scott Miller, MD, FACOG, FACS, and Angeles Alvarez Secord, MD, MHSc, provide expert insights on key data presented at SGO 2022 for ovarian, endometrial, and cervical cancers regarding: Results from the prospective phase III PRIME study of an individualized dose for niraparib vs placebo maintenance in newly diagnosed advanced ovarian cancer Final OS analysis from phase III SO...

In this episode for all healthcare professionals and any patient-facing clinical staff, Nelson F. Sanchez, MD, shares key insights on the need for equitable, compassionate healthcare for transgender individuals, along with practical guidance based on his clinical experience caring for these patients. Topics include: Communication and physical exam skills Specific clinical care needs of transgender...

In this episode, Pharmacist Olivia Buckoski shares her experience undergoing medical and social transition and offers advice from the perspective of both a transgender person and healthcare professional on caring for transgender individuals. Topics include: Importance of educating entire care team about needs of transgender individuals, starting with the waiting room Specific advice for the exam r...

In this episode, Jyoti D. Patel, MD, and Ani Balmanoukian, MD, discuss several studies investigating agents targeting TIGIT, an emerging immune checkpoint target with promising results in PD-L1-positive NSCLC. The episode includes a review of phase II data on the use of tiragolumab plus atezolizumab in NSCLC, the use of PD-L1 as a marker of response, the potential role of anti-TIGIT therapies in s...

In this episode, Jyoti D. Patel, MD, and Diwakar Davar, MD, discuss several studies investigating agents targeting TIGIT, an emerging immune checkpoint target with promising early-phase clinical trial results. The episode includes a comprehensive explanation of TIGIT, how the TIGIT pathway functions, and the potential role of TIGIT inhibition for the treatment of cancer, including analyses from on...

In this episode, Nilofer S. Azad, MD, and Kanwal Raghav, MD, discuss current and emerging uses of regorafenib and TAS-102 in later-line treatment of patients with mCRC, with topics including: Current use of regorafenib and TAS-102 monotherapy Combination therapy with regorafenib and PD-1 inhibitors Adding bevacizumab to TAS-102 Presenters: Nilofer S. Azad, MD   Professor , Oncology   Sidney Kimmel...

In this episode, Jeff P. Sharman, MD; Matthew S. Davids, MD, MMSc; and Anthony Mato, MD, MSCE, answer questions from a live CCO webinar on current best practices and  emerging strategies in BTK inhibitor therapy for patients with chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), with questions including: For patients with CLL, when should acalabrutinib-, ibrutinib-, or venetoclax-...

In this episode, Lipika Goyal, MD, leads an engaging discussion with Christine Chio, PharmD, BCOP, and Caroline Kuhlman, NP, on current treatment of patients with cholangiocarcinoma. Topics include: Initial diagnosis Biomarker testing to guide treatment with immunotherapies and targeted agents Adverse event management Strategies for counseling patients Presenters: Christine Chio, PharmD, BCOP Clin...

In this podcast episode, Amy DeZern, MD, MHS, Daniel Pollyea, MD, MS, and Amer Zeidan, MBBS, discuss challenging cases in MDS, including Treatment for MDS after ESA failure Strategies for patients with intermediate- or high-risk MDS Luspatercept therapy in MDS MDS case challenges Link to full program, including downloadable slidesets: https://bit.ly/3tYwcYu Presenters:  Amy E. DeZern, MD, MHS Asso...

In this episode, Dr Prithviraj Bose, Pharmacist Caitlin R. Rausch, and Nurse Practitioner Ilene A. Galinsky discuss incorporating KIT-targeted therapies into management of patients with advanced systemic mastocytosis. Topics include: Diagnosis and prognosis of advanced systemic mastocytosis Clinical trial data on efficacy of avapritinib and midostaurin Monitoring for and managing key toxicities wi...

In this episode, Julie M. Vose, MD, MBA;  Brad S. Kahl, MD; and  John P. Leonard, MD, discuss treatment approaches for patients with B-cell lymphomas, including information on:  Follicular lymphoma Marginal zone lymphoma Mantle cell lymphoma Diffuse large B-cell lymphoma Posttransplant lymphoproliferative disorder Presenters: Julie M. Vose, MD, MBA Chief, Division of Oncology and Hematology Neuman...

In this podcast episode from Clinical Care Options (CCO), Josep M. Llovet, MD, PhD, and Markus Peck-Radosavljevic, MD, MBA, discuss second line treatment of patients with advanced hepatocellular carcinoma. Topics include: Available agents for the management of advanced hepatocellular carcinoma in the second line The current role of tyrosine kinase inhibitors in second-line treatment of advanced he...

In this episode, Eileen M. O’Reilly, MD, and Naureen Starling, MD, FRCP,  discuss emerging therapeutic strategies involving PARP inhibitor therapy in the treatment of pancreatic cancer. Topics include: Current treatment landscape and testing in the United States vs the United Kingdom   Testing for molecular subgroups beyond BRCAm Using PARP inhibitors in earlier stages of the disease Learning from...

In this episode,Brian G.M. Durie, MD; Thomas G. Martin, MD; Philippe Moreau, MD; S. Vincent Rajkumar, MD; and Jesús F. San-Miguel, MD, PhD, discuss treatment approaches for multiple myeloma using example patient cases. Smoldering myeloma Induction therapy for autologous stem cell transplant–eligible patients First-line approaches for autologous stem cell transplant–ineligible patients Treatment af...

In this episode, Keith R. McCrae, MD; Nichola Cooper, MD; and Rachael Grace, MD, MMSc,provide expert insights on immune thrombocytopenia management, along with addressing frequently asked questions from a live CCO symposium. Topics include: New and emerging therapeutic options Special patient populations, including children The management of immune thrombocytopenia COVID-19 vaccinations and immune...

In this episode, Ara Metjian, MD; Paul Coppo, MD, PhD; and Marshal Mazepa, MD, answer questions from an audience of healthcare professionals on topics related to the management of acquired thrombotic thrombocytopenic purpura (aTTP), including:   Rationale of the CAPLAVIE regimen of caplacizumab with corticosteroids and rituximab in aTTP in the acute phase Data for caplacizumab in pediatric patient...

In this episode, Steven M. Horwitz, MD; Francine Foss, MD; and Barbara Pro, MD, answer questions from an audience of healthcare professionals on topics related to the management of patients with T-cell lymphomas including: Threshold of CD30 positivity useful to inform brentuximab vedotin use in patients with CTCL and PTCL Managing relapsed mycosis fungoides after allogeneic SCT Experience with ALK...

In this podcast episode, Conor Ernst Steuer, MD, a medical oncologist; Frank Schneider, MD, a pathologist; and Elise Hitron, MSN, FNP-C, a phase I clinical trials nurse practitioner, engage in a multidisciplinary discussion of the latest management strategies for EGFR-mutated NSCLC. Topics include: Testing for targetable biomarkers Talking with patients about biomarker testing Frontline therapy fo...

In this podcast episode, 3 experts answers questions on the management of hemophilia A from a live webinar. Topics include:  Which patients should have pharmacokinetic-guided therapy? Toxicities with PEGylated extended half-life products Factor VIII and bone health Factor VIII peaks, thrombotic risk, and cardiovascular disease Choosing between extended half-life products and emicizumab for active...

In this podcast episode, Ashley Leak Bryant, PhD, RN, OCN, FAAN, discusses therapeutic options for younger, fit patients with AML and no targetable mutations. Topics include: Induction chemotherapy and consolidation therapy Use of gemtuzumab ozogamicin Management of sinusoidal obstruction syndrome   Nursing considerations for younger, fit patients with AML Presenter: Ashley Leak Bryant, PhD, RN, O...

In this podcast episode, Sarah M. Tinsley, PhD, APRN, AOCN, discusses targeted therapy with FLT3 and IDH1/2 inhibitors in AML, with a focus on the nursing perspective. Topics include: Approved and emerging treatment options for FLT3-mutated AML Management of adverse events associated with FLT3 inhibitors Therapies for IDH1- and IDH2-mutated AML Identifying and managing differentiation syndrome ass...

In this podcast episode, Sarah M. Tinsley, PhD, APRN, AOCN, discusses management strategies for secondary AML and novel therapies currently in clinical trials for AML. Topics include: Liposomal cytarabine plus daunorubicin for secondary AML An overview of emerging immune-based strategies for AML Evidence on immune-based therapies, including agents targeting CD47, TIM3, and bispecific antibodies Pr...

In this podcast episode, Ashley Leak Bryant, PhD, RN, OCN, FAAN, discusses acute myeloid leukemia and management approaches for patients unfit for intensive chemotherapy, with a focus on the nursing perspective. Topics include: An overview of AML Identifying patients unfit for intensive therapy Treatment options for unfit patients including venetoclax combinations Adverse event profiles of treatme...

In this podcast episode,  Ashley Leak Bryant, PhD, RN, OCN, FAAN, discusses management strategies for lower-risk myelodysplastic syndrome (MDS) with a focus on the nursing perspective. Topics include Risk scoring and treatment algorithms Current and ongoing clinical trials in the lower-risk MDS setting Adverse event profiles of current treatment options Nursing considerations for managing a patien...