CRISPR Cuts

Dr. Bill Skarnes, Professor at The Jackson Laboratory , chats about how CRISPR edited stem cells are becoming a gold standard to study gene function and disease modeling. 

Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interactions and developing ways for treating fungal biofilms.

In this interview, Paul Dabrowski, CEO of Synthego, talks about how Synthego got started, his mantra behind leading the company, and future directions. He also offers insights into Synthego’s unique capabilities⁠—the powerful combination of engineering and biology that enable scaling.

CRISPR has great potential in therapeutics, but CRISPR delivery in vivo remains a challenge. Researcher Dana Foss discusses her lab’s novel approach for specific delivery of CRISPR components in cells and tissues.

CRISPR is going beyond gene editing into a new area: diagnostics. Omar Abudayyeh and Jonathan Gootenberg, co-founders of SHERLOCK Biosciences, talk about the present advances and future of CRISPR diagnostics. 

Kiana Aran, a biomedical engineering expert, talks about her research on CRISPR-Chip, a new biosensor that combines CRISPR & electronics to detect specific genes in genomic DNA.

Megan Hochstrasser, Science Communications Manager at the Innovative Genomics Institute, talks about the importance of CRISPR science communication and the ongoing efforts at IGI to help people understand this genome engineering tool.

Andre Watson, CEO of Ligandal, talks about how his company is improving the payload delivery of gene therapy, making it more accurate and efficient, to make new gene therapy a reality for the public.

Biotech and biopharma companies are in a phase of accelerated growth. Alex Philippidis, a science journalist at Genetic Engineering & Biotechnology News discusses the changing face of big pharma, biotech, and CRISPR gene editing industries, as they raise more money and the world changes around them.

Dr. Avery Posey is leading the charge on CAR T cell therapy research to bring this technology to cancer patients as soon as possible. Learn how CAR T works, what stage it’s in now, and how it will help revolutionize the treatment of cancer.  

Trevor Martin, CEO of Mammoth Biosciences, talks about the science behind CRISPR diagnostics, and what Mammoth is doing to bring it to consumers in the next decade.

In this Holiday-special mash-up episode, CRISPR Cuts teams up with Curiosity podcast to discuss the ins and outs of CRISPR. Gear up, it's going to be a fun ride!

Andrew Porterfield is a scientific marketing consultant, science journalist, and all around science communicator. We caught up with Andrew to discuss the latest news about how CRISPR is impacting the agriculture industry and how the various regulatory decisions related to this technology may shape its use and adoption in different parts of the world.

Alison Van Eenennaam is a geneticist at UC Davis, primarily interested in using CRISPR and other DNA-based biotechnologies in cattle production and agricultural systems. Learn about her exciting projects, ranging from "All Boys" cattle to hornless dairy cows, and the technical difficulties of working with large mammals in this episode.

Gene drives have frequently been in the news in the past few years. In this episode, we discuss what exactly gene drives are, their applications, and how scientists are ensuring that they are used responsibly. Tune in to hear what researchers Anna Buchman from UCSD and Kevin Esvelt from MIT had to say.

Dr. Ania Wronski, Product Manager for the Engineered Cells portfolio at Synthego, discusses how their new engineered cells products are enabling CRISPR access to researchers worldwide. Learn about the different ways in which researchers use knockout cell pools & their advantages over RNAi.

What do you think of when you hear the term "transgenic animal"? The hippogriff from Harry Potter? A mouse model to study diabetes? Kevin and Minu discuss what transgenic animals are, how they are used in research, and how CRISPR has changed the transgenic game. After listening, head over to The Bench blog to read more about CRISPR and transgenic animals .

It's not every day you get to meet one of your idols! Minu and Kevin caught up with Carl Zimmer, an award-winning New York Times columnist and science journalist. Minu chatted with Zimmer and got a rare behind-the-scenes glimpse into his latest book "She Has Her Mother's Laugh" and discussed his views on CRISPR and genomics. 

Reed Kelso, Head of Cell Engineering Research and Applications at Synthego, is a bio-wizard. In this episode, Kevin & Minu catch up with Reed about his role at Synthego and the day-to-day operations at the fast paced start-up. Reed talks about the revolutionary engineered cells products that he and his team recently launched & the hard work behind this amazing achievement. He also speculates about...