CorConsult Rx: Evidence-Based Medicine and Pharmacy

On this episode, we are joined by Brian Gilbert, PharmD, BCPS,  BCCCP and two of his residents. We review some tactics for standing out during the residency showcase at Midyear. Dr. Gilbert also discusses the critical care residency program that he runs in Kansas. If you have any questions, you can reach Dr. Gilbert at: brian.gilbert.pharmd@gmail.com Below is the booth details if you're inter...

On this episode, we are joined by PGY-1 resident Patrick Key, PharmD. We review the signs and symptoms of schizophrenia. We then discuss the pharmacology of first and second generation antipsychotics. We end with a few possible pharmacotherapy strategies for treating a patient's schizophrenic symptoms.  If you have any questions, reach out to us on any of the following: Mike - mcorvino@corcon...

On this episode, we briefly describe a few common types of seizures. We then review the adverse effects, mechanism, interactions, and several clinical pearls for various antiepileptic medications. If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podca...

On this episode, we review the treatment options of osteoarthritis. We discuss the various joints and comorbidities that can guide treatment selection. We also compare and contrast three different sets of guidelines currently available.  The link for the OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis can be found at the following link:  ht...

On this episode, we give a general overview of the treatment options available for osteoporosis. We discuss osteoporosis seen in men and  postmenopausal women as well as drug induced osteoporosis.  If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx...

On this episode we discuss the 2019 GOLD guidelines for the management of COPD. We review the POET, FLAME, and other trials to explain some of the recommendations. We have a breakdown of all the drugs and at what point they are possibly introduced into the pharmacotherapy plan. If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corc...

On this episode we are joined by Dr. Brian Gilbert, PharmD, BCPS, BCCCP. Dr. Gilbert provides an overview of fluid management for managing various conditions in a critical care setting. He also published a review article entitled Strategies for the Management of Sepsis that includes a review of fluids. The link is listed below: http://acc.aacnjournals.org/content/30/1/5.full If you have any questi...

On this episode we review obsessive-compulsive disorder. We start by giving a brief overview and background of the disorder. We then discuss some first-line treatment options. We then review the literature that supports various augmentation strategies. The website that I reference for the psychiatry CME can be found at the link below: https://psychopharmacologyinstitute.com The augmentation strate...

On this episode, we are joined by two MUSC 4th year pharmacy students, Ian and Allison. We discuss the CREDENCE trial (NEJM 2019) that showed the benefit of canagliflozin for renal protection in patients with diabetes. We also review the pathophysiology, diagnosis, and treatment of urinary tract infections.  If you have any questions, reach out to us on any of the following: Mike - mcorvino@c...

On this episode, we are joined by Zach Posey. Zach is a 4th year pharmacy student at the Medical University of South Carolina. He recently received honors for his Grand Rounds presentation on this subject. We cover some background on statins, and review the potential biochemical processes involved with statin induced glucose dysregulation. We also cover a few trials that look at the risk of diabet...

On this episode, we answer some common questions from the world of community pharmacy. One of our listeners compiled these questions and e-mailed them to us. Some examples include the difference between diltiazem formulations, doxycycline monohydrate vs hyclate, and methylphenidate LA vs CD. If you have any questions, reach out to us on any of the following:Mike - mcorvino@corconsultrx.com Cole -...

On this episode, we give a basic overview of drug absorption, distribution, metabolism, and excretion. We discuss the CYP450 enzyme system, various phase II enzymes, P-glycoprotein, drug interactions, and other important concepts. If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media pl...

On this episode, we review the pathophysiology and pharmacotherapy involved with the treatment of pulmonary arterial hypertension. If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment...

Last November we discussed the updated lipid guidelines. We wanted to revisit the treatment options for dyslipidemia and discuss some of the updated data that has been recently released. We review pathophysiology, as well as statin and non-statin therapy options. We walk through the algorithms for secondary prevention for patients with ASCVD, treatment for hypercholesterolemia, primary prevention,...

On this episode, we review various disease states by going through a patient case. We talk about diabetes management, HFrEF, hypertension, dyslipidemia, ASCVD, osteoarthritis, neuropathy, depression, etc. The patient case will be available on our website under the "Show Notes" heading. Let us know if you would handle any of the disease states differently. Check out our podcast merchandise at https...

On this episode, we discuss the updated 2019 GINA (Asthma) guidelines. We review basic pathophysiology and diagnostics. We then examine the updated treatment options including the use of PRN inhaled ICS + formoterol in place of an albuterol inhaler. Below is a link to the GINA pocket guidelines: https://ginasthma.org/wp-content/uploads/2019/04/GINA-2019-main-Pocket-Guide-wms.pdf If you have any qu...

On this episode, we review various disease states by going through a patient case. We talk about diabetes management, HFrEF, hypertension, dyslipidemia, ASCVD, osteoarthritis, neuropathy, depression, etc. The patient case will be available on our website under the "Show Notes" heading. Let us know if you would handle any of the disease states differently. Check out our podcast merchandise at https...

On this episode we give a brief overview of the management of both hepatitis A and B. We also review ACIP immunization recommendations for both diseases. This review only covers the surface of these disease and we greatly encourage you to read further on your own. Below is the link to the Infectious Disease Society of America guidelines: https://www.idsociety.org/globalassets/idsa/practice-guideli...

This episode was originally supposed to be a simple topic discussion between my student and me. We ended up recording it as a podcast episode that will hopefully serve as a quick review of material that has been covered in other episodes. The patient case that we discussed during the episode: 63 y/o female with diabetes, HFrEF, hypertension. Medications: A1c = 8.9% HFrEF – EF = 30% BP = 154/84 mmH...

On this episode, we give an overview of allergic rhinitis. We discuss some background information, pathophysiology, and non-pharmacological treatment options. Then we review all the different pharmacotherapy options currently available.  If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other soc...

On this episode, we are joined by MUSC College of Pharmacy P4 Ryan Rosenblatt. We discuss some pathophysiology and microbiology involved with urinary tract infections. We then review some of the pharmacotherapy options available for treatment.  If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and ot...

On this episode, we review ulcerative colitis. We compare and contrast the differences between ulcerative colitis and crohn's disease. We walk through most of the treatment options available as well as the updated 2019 guidelines.  The 2019 UC guidelines from the American College of Gastroenterology can be found at the following link: http://gi.org/clinical-guidelines/clinical-guidelines-sort...

On this episode, we provide a very brief overview of hyperthyroidism. We discuss some of the causes as well as thyrotoxicosis and thyroid storm.  We kept this discussion simple and didn't go into much detail. We will provide a more extensive review in later episodes.   If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanso...

On this episode, we are joined by Brian Gilbert, PharmD, BCPS, BCCCP, David Moran, PharmD, and Jacob Reeder, PharmD, BCCCP to discuss andexanet alfa (Andexxa). We contrast the DOAC benefits that are popular among the ambulatory care community with the DOAC risks that the critical care teams often deal with. Dr. Gilbert leads the review of some concerns that many clinicians have with Andexxa. We re...

On this episode, we give an overview of glaucoma. We review some background information including the different classifications of glaucoma and pathophysiology. We then discuss the various classes of medications that are used to reduce and maintain intraocular pressure. If you have any questions, reach out to us on any of the following: Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx...