CorConsult Rx: Evidence-Based Medicine and Pharmacy

On this episode, we review the management of hypothyroidism. We focus on levothyroxine as the foundation for a patient treatment. We also discuss the contraversial issue of using synthetic T3 (liothyronine) as an augmentation option for certain patients. The link to the Medscape article, Why the Hesitancy in Recommending Combination T3/T4 Therapy with Dr. Kaniksha Desai, MD and Dr. Antonio Bianco,...

On this episode, we discuss the various treatment options for community acquired pneumonia. We compare and contrast the differences in treating a patient with and without comorbidities in the outpatient setting as well as non-severe and severe CAP in the inpatient setting. We also review some basics for the various antibiotics used in CAP. Cole and I are happy to share that our listeners can claim...

On this episode, we discuss the management of substance abuse disorder. We review the pharmacotherapy/psychotherapy options for treating the abuse of alcohol, cocaine, methamphetamine, cannabis, benzodiazepines, and opioids. Make sure to check out our previous episode that covers opioid use disorder specifically.  Cole and I are happy to share that our listeners can claim ACPE-accredited cont...

On this episode, we discuss the pharmacotherapy options available for smoking cessation. We start with some background info including pathophysiology, psychology models applicable to smoking cessation, and nicotine dependence assessments.  We review varenicline, nicotine replacement therapy in various forms, bupropion SR, and others.  Cole and I are happy to share that our listeners can...

On this episode, we go over a pharmacotherapy plan for a patient with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and OSA. Episode 227 Patient Case Information 57-year-old male with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye disease, constipation, GERD, and OSA comes to your clinic to establish care. His pr...

On this episode, we discuss the considerations and possible changes to a patient's general depression regimen when they have various comorbidities or other circumstances that affect their health . The comorbidities/situations that we cover include: patients with coronary artery disease, patients over the age of 65, patients that are pregnant, chronic pain, OCD, ADHD, PTSD, and more. We also review...

On this episode, we discuss Vowst, the oral fecal microbiota product for preventing the recurrance of C. diff infection. We review Vowst's dosing, administration, drug-drug interactions, clinical trial data, and more.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well a...

On this episode, we review the various pharmacotherapy options that are used in the management of osteoporosis. We go over bisphosphonates, denosumab, parathyroid hormone analogics, and romosozumab.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide list...

On this episode, we compare and contrast the various pharmacotherapy options used to manage acne vulgaris. We review topical retinoids, topical and oral antibiotics, androgen-receptor inhibitors, oral contraceptives, spironolactone, and oral isotretinoin. We close with a patient case to summarize the episode.  Cole and I are happy to share that our listeners can claim ACPE-accredited continui...

On this episode, we discuss the management of ulcerative colitis and review the various pharmacotherapy options that are currently available.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing...

On this episode, we are joined by Dr. Will Flanary (AKA Dr. Glaucomflecken) and Kristin Flanary (AKA Lady Glaucomflecken). Dr. Flanary is a practicing ophthalmology who also creates hilarious skits incorporating a wide range of characters who worked at a fictional hospital called "Glaucomflecken General." As Dr. Glaucomflecken, he has collaborated with the US Surgeon General, given the 2022 Yale M...

On this episode, we review the pharmacotherapy options available for managing primary-open angle glaucoma. We discuss prostaglandin analogs, beta-blockers, alpha-2 agonists, carbonic anhydrase inhibitors, cholinergics, rho kinase inhibitor, and more. We also briefly review angle-closure glaucoma to finish the episode.  Cole and I are happy to share that our listeners can claim ACPE-accredited...

On this episode, we are joined by long-time friend of the show, Amelia Furbish, PharmD, PhD candidate, to discuss the emergence of psychedelics and their potential role in managing behavioral health conditions. If you are interested in learning more about medicinal psychedelics, we encourge you to check out and consider becoming a member of the Psychedelic Pharmacists Association (see the website...

On this episode, we discuss the management and treatment of irritable bowel syndrome (IBS). We review the various medications recommended published in the 2020 American College of Gastroenterology and the 2022 American Gastroenterological Association treatment guidelines. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast e...

On this episode, we review the recently published CLEAR-outcomes trial that was looking at bempedoic acid's (Nexletol) ability to lower the risk of CV events in patients who were unable to tolerate statins at their recommended doses. While recording this episode, we used the trial summary written by Dr. Alex Poppen, PharmD who is the author/owner of the book High-Powered Medicine: Landmark Clinica...

On this episode, we review the treatment and management of various types of anemia. We discuss iron-deficiency anemia, B-12 and folate dificiency anemia, anemia due to CKD, anemia due to chronic disease (inflammation), and aplastic anemia.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued t...

On this episode we cover three different topics that have been in the medical news lately. First, we compare/contrast the blood pressure goals that where published by the American College of Physicians with other prominant hypertension guidelines. Second, we discuss the semaglutide "side effect" that has been coined Ozempic Face. Finally, Cole reviews some literature surrounding the health benefit...

On this episode we review typical (first generation) and atypical (second generation) antipsychotics. We discuss receptor signaling, various adverse effects, and specific clinical pearls for the individual medications in the antipsychotic class.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have conti...

On this episode, we discuss dosing antihypertensives at bedtime compared to the morning and if it impacts patient outcomes. We review the MAPEC, Hygia, and TIME studies as well as other editorials on this debated topic. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com...

On this episode we discuss the new drugs that have been approved in 2023 so far. We review Leqembi (lecanemab-irmb) injection for Alzheimer's disease, Airsupra (albuterol and budesonide) inhalation for as-needed use in asthma, and Brenzavvy (bexagliflozin) for type 2 diabetes. We also mention Rykindo (risperidone) ER injection, but we didn't go into much detail since we've gone over risperidone in...

On this episode, we discuss the pharmacotherapy options for managing obsessive compulsive disorder (OCD). We based our discussion on the treatment algorithm created by Dr David Osser. All of Dr. Osser's work with the Psychopharmacology Algorithms Project at the Harvard South Shore Psychiatry Residency Training Program can be found at the following website: Cole and I are happy to share that our li...

On this episode, Cole and I review some of the updates that were published in the 2023 American Diabetes Association guidelines. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit fo...

Below is the patient case information: 63-year-old white male. Problem List Bipolar II disorder Insomnia Epilepsy (tonic-clonic seizures) Dyslipidemia/hypertriglyceridemia Hypertension Recent weight gain History of hyponatremia  Diabetes type 2(controlled) Medications Clonazepam 2 mg QHS Risperdal 2 mg twice daily Carbamazepine 200 mg twice daily Divalproex DR 500 mg three times daily Levetir...

On this episode, we discuss the management of insomnia disorder. We review the criteria necessary for an insomnia disorder diagnosis. We then compare and contrast the pharmacotherapy options such as non-benzodiazepine hypnotics, benzodiazepines, anti-depressants, orexin receptor antagonists, and more.  Cole and I are happy to share that our listeners can claim ACPE-accredited continuing educa...

On this episode, we discuss the various therapeutic options for managing a patient with chronic pain. We discuss nonpharmacological options, anti-inflammatory medications, and other non-opioid pharmacological options. Then, we compare and contrast some of the commonly used opioids and discuss some of the nuances/clinical pearls for individual opioids. Cole and I are happy to share that our listene...