ReachMD

CME

Science EN ↓ 402 episodes

Author

ReachMD

Category

Science

Podcast website

reachmd.com

Latest episode

Jul 9, 2026

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Episodes

IgAN Management Into Practice: Evolving Guidelines & Targeted Therapies 19.11.2025

Faculty: Jörg Latus, MD Faculty: Jürgen Floege, MD Dr. Jürgen Floege, co-chair of the KDIGO Work Group, and Dr. Jörg Latus review the updated KDIGO 2025 guidelines for managing immunoglobulin A nephropathy (IgAN) and IgA vasculitis (IgAV), which emphasize diagnostic criteria, proteinuria-based treatment thresholds, and revised therapeutic goals. The discussion focuses on the new KDIGO proteinuria...

Engaging Your Patient: Shared Decision-Making in HF With LVEF ≥40% 18.11.2025

Faculty: Scott Solomon, MD Enhance your ability to apply shared decision-making in patients with HF and LVEF ≥40%. Through real-world clinical vignettes, Dr. Scott Solomon illustrates how to uncover patient goals, clearly communicate risks and benefits, and build collaborative treatment plans. The session emphasizes early use of SGLT2 inhibitors and finerenone to reduce hospitalizations, improve q...

Looking Ahead: Integrating CDH6-Targeted Therapies Into Ovarian Cancer Treatment Paradigms 14.11.2025

Faculty: Joyce F. Liu, MD, MPH Faculty: Kathleen Moore, MD, MS Platinum-resistant ovarian cancer remains a major clinical challenge, characterized by high recurrence rates, limited durable treatment options, and poor overall survival outcomes. Cadherin-6 (CDH6)-targeted antibody-drug conjugates (ADCs) represent a novel therapeutic approach that leverages the tumor-specific expression of CDH6 to de...

Safety and Tolerability of CDH6-Directed Antibody-Drug Conjugates 14.11.2025

Faculty: Kathleen Moore, MD, MS Platinum-resistant ovarian cancer remains a major clinical challenge, characterized by high recurrence rates, limited durable treatment options, and poor overall survival outcomes. Cadherin-6 (CDH6)-targeted antibody-drug conjugates (ADCs) represent a novel therapeutic approach that leverages the tumor-specific expression of CDH6 to deliver potent cytotoxic agents d...

Clinical Evidence: Insights From Early Trials of CDH6-Targeted Therapies 14.11.2025

Faculty: Joyce F. Liu, MD, MPH Platinum-resistant ovarian cancer remains a major clinical challenge, characterized by high recurrence rates, limited durable treatment options, and poor overall survival outcomes. Cadherin-6 (CDH6)-targeted antibody-drug conjugates (ADCs) represent a novel therapeutic approach that leverages the tumor-specific expression of CDH6 to deliver potent cytotoxic agents di...

MOA: CDH6-Targeted Antibody-Drug Conjugates 14.11.2025

Faculty: Kathleen Moore, MD, MS Platinum-resistant ovarian cancer remains a major clinical challenge, characterized by high recurrence rates, limited durable treatment options, and poor overall survival outcomes. Cadherin-6 (CDH6)-targeted antibody-drug conjugates (ADCs) represent a novel therapeutic approach that leverages the tumor-specific expression of CDH6 to deliver potent cytotoxic agents d...

Navigating the Therapeutic Landscape of Platinum-Resistant Ovarian Cancer 14.11.2025

Faculty: Joyce F. Liu, MD, MPH Platinum-resistant ovarian cancer remains a major clinical challenge, characterized by high recurrence rates, limited durable treatment options, and poor overall survival outcomes. Cadherin-6 (CDH6)-targeted antibody-drug conjugates (ADCs) represent a novel therapeutic approach that leverages the tumor-specific expression of CDH6 to deliver potent cytotoxic agents di...

The Fifth Pillar? Closing the Gap in HFrEF 14.11.2025

Faculty: Carolyn S. P. Lam, MBBS, PhD, MRCP, MS, FACC, FAMS, FESC Faculty: Javed Butler, MD Faculty: Stephen J. Greene, MD, FACC, FHFSA For patients with heart failure with reduced ejection fraction (HFrEF), optimizing therapy is an important part of treatment and care. But not all patients may be reaching their treatment goals and can continue to face substantial residual risk despite the use of...

Treating MASH With Compensated Cirrhosis: A Serious Unmet Need 11.11.2025

Faculty: Naim Alkhouri, MD, FAASLD, DABOM Metabolic dysfunction-associated steatohepatitis (MASH) with compensated cirrhosis is associated with poor prognosis due to a high risk of hepatic decompensation, hepatocellular carcinoma, cardiovascular events, and death. Using noninvasive diagnostic tools like FIB-4, VCTE, and Agile 4, clinicians can accurately identify cirrhosis and clinically significa...

Advancing Clinical Expertise in CELMoDs: Transforming Multiple Myeloma Treatment 10.11.2025

Guest: Joshua Richter, MD This activity will cultivate familiarity with the emerging CELMoD treatment class poised to transform the management of newly-diagnosed and R/R MM. With a higher affinity for cereblon than their predecessors, CELMoDs represent a new, distinct generation of immunomodulatory drugs with the potential to bridge longstanding treatment gaps for patients exhibiting inadequate re...

Optimizing the Role for Corticosteroids Within the Evolving DMD Treatment Landscape 07.11.2025

Host: Stephen Chrzanowski, MD, PhD Guest: Aravindhan Veerapandiyan, MD Corticosteroids remain a cornerstone in Duchenne muscular dystrophy (DMD) management, but evolving therapies demand a more nuanced approach. This case-based activity explores how to proactively monitor and manage corticosteroid-associated side effects through interdisciplinary care coordination. Strengthen your care strategy as...

Updates in Major Depressive Disorder with Insomnia 07.11.2025

Faculty: Michael E. Thase, MD Faculty: Andrew Krystal, MD Approximately 75% to 90% of patients with depression experience insomnia. This means that a very significant portion of individuals struggling with depression also have difficulty sleeping. Join Drs. Michael Thase and Andrew Krystal for this expert discussion to learn about the most recent data presented at the Psych Congress 2025 in San Di...

The Hidden Threat: Transforming CKD Care Across the Diabetes Spectrum 05.11.2025

Faculty: prof. Hiddo Heerspink Faculty: Peter Rossing, MD, DMSc Faculty: Paola Fioretto, MD Chronic kidney disease (CKD) is a common complication in type 2 diabetes that is closely linked to cardiovascular risk and often diagnosed late. Early detection with UACR and eGFR, plus treatment with therapies such as SGLT2 inhibitors, finerenone, and GLP-1 receptor agonists, has transformed treatment and...

From Pain to Possibilities: Safe Opioid Use and Treatment of Patients with Pain 01.11.2025

Host: Lisa Phipps, PharmD, PhD Guest: Michael Sprintz, DO, DFASAM Guest: Amanda Zimmerman, PA-C This Opioid Analgesic REMS webcast provides an FDA Blueprint-aligned learning experience to support safe, compassionate pain management through thorough assessment and individualized treatment planning. Also covered is counseling on safe opioid use, storage, and disposal; monitoring for misuse; and scre...

Breaking the Cycle: Prioritizing Weight Loss to Improve OSA Management 31.10.2025

Guest: Jaime Almandoz, MD, MBA, MRCPI, FTOS, DABOM Guest: Radhika S. Breaden, MD, MPH, DABMS, DABOM Guest: H-C Carol Huang, BHB, MBChB, FRACP Guest: Babak Mokhlesi, MD, MSc Guest: Amanda J. Piper, PhD Guest: Rafael Sepulveda, MD, DABMS, DABOM Guest: Audrey Wells, MD On-demand webcast of expert faculty presentation on the connection between obstructive sleep apnea (OSA) and obesity, including strat...

Case-Based Approach: Optimizing Cardio-Kidney-Metabolic Outcomes in Individuals With T2D & CKD 31.10.2025

Faculty: Rajiv Agarwal, MBBS, MD, FASN, BRCU Faculty: Prof. Dr. Francesc Xavier Cos Claramunt This case-based program explores the missed opportunities in CKD detection and treatment in a patient with type 2 diabetes. Drs. Agarwal and Cos emphasize the role of primary care physicians in annual UACR screening, which can reveal kidney injury long before symptoms occur. With new evidence from the CON...

Are All VMAT2s The Same? Data Driven Treatment Decisions for Tardive Dyskinesia 30.10.2025

Faculty: Christoph U. Correll, MD Faculty: Jonathan M. Meyer Tardive Dyskinesia (TD) is an involuntary movement disorder that can develop as a side effect of taking antipsychotic and other medications. Currently there are 2 FDA approved VMAT2 inhibitors for treating TD. Join Drs. Cristoph U. Correll and Jonathan M. Meyer for this expert discussion on the most recent data presented at the Psych Con...

Mechanism-Driven gMG Therapy: FcRn Antagonists and the Rise of Precision Neurology 29.10.2025

Faculty: Neelam Goyal, MD Faculty: Christyn Edmundson, MD This Clinical Countdown addresses key challenges in diagnosing and managing generalized myasthenia gravis (gMG), with a focus on FcRn antagonists. Drs. Edmundson and Goyal review diagnostic challenges in gMG, along with the mechanism of FcRn blockade and how it compares to traditional therapies such as corticosteroids, IVIG, and plasma exch...

The Patient-Clinician Connection in Managing CKD-aP 24.10.2025

Guest: James Burton, DM, FRCP Guest: Lucio Manenti, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including ho...

Improving Sleep and Mental Health in Patients with CKD-aP 24.10.2025

Guest: Leonie Kraft, MD Guest: Lucio Manenti, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including how to u...

Kappa-Opioid Settings: Real-World Evidence Insights 24.10.2025

Guest: Lucio Manenti, MD, PhD Guest: Emilio Sanchez, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including h...

Is CKD-aP Hiding in Your Dialysis Center? 24.10.2025

Guest: James Burton, DM, FRCP Guest: Emilio Sanchez, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including h...

Elevating CKD-aP Care: New Frontier 24.10.2025

Guest: James Burton, DM, FRCP Guest: Lucio Manenti, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including ho...

CKD-aP Treatment Tool Kit 24.10.2025

Guest: Leonie Kraft, MD Guest: Emilio Sanchez, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including how to...

CKD-aP or Something Else? Decoding the Diagnosis 24.10.2025

Guest: James Burton, DM, FRCP Guest: Emilio Sanchez, MD, PhD Despite its prevalence, chronic kidney disease–associated pruritus (CKD-aP) remains underrecognized and undertreated in patients undergoing hemodialysis, owing to its complex pathophysiology, diagnostic challenges, symptom cluster etiology, and multidimensional impact on quality of life. Learn best practices from the experts, including h...

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