CEimpact Podcast

Long COVID, or PostAcute Sequelae of SARS-CoV-2 Infection (PASC), was identified early in the pandemic. With over 200 symptoms attributed to PASC, join host, Geoff Wall, as he evaluates a seminal paper describing the diagnostic criteria, symptoms, and incidence of Long COVID.   The GameChanger The PASC score can be used to detect Long COVID and help establish patients into care.   Host Geoff Wall,...

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Non-alcoholic fatty liver disease (NAFLD) is a primary cause of chronic liver disease and cirrhosis. Join host, Geoff Wall, as he evaluates new data on the diagnosis and treatment of NAFLD.   The GameChanger Historical treatment of NAFLD includes beta-blockers, diuretics, and lactulose for hepatic encephalopathy. Newer agents include statins, pioglitazone, and even vitamin E. Host Geoff Wall, Phar...

Many of us avoid giving feedback because it can feel negative and uncomfortable. We’re afraid of a poor reaction from the student and we really don’t want to hurt their feelings – after all – they already have so much pressure on them. And let’s be honest - sometimes, we just want to be liked. And yet as preceptors, giving good feedback is probably one of the most important jobs we have. If our le...

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Half of patients with heart failure have Heart Failure with Preserved Ejection Fraction (HFpEF).  Join host, Geoff Wall, as he talks about the new guidelines from the American College of Cardiology for diagnosis, treatment, and challenges in therapy for persons with HFpEF. The GameChanger HFpEF is the fastest growing cause of heart failure and is often difficult to diagnose. New therapies are show...

Adulteration of medications of abuse is a rampant issue in the US. Most attention is on opioids; however, benzodiazepine adulteration is occurring – with sulfonylureas. Join host, Geoff Wall, as he talks about managing emergent hypoglycemia episodes.   The GameChanger Several case reports have detailed patients unresponsive due to severe hypoglycemia caused by mistaken sulfonylurea ingestion. Trea...

Septic shock has a 40% mortality rate in many patients. Methylene blue has been shown in small non-controlled case series to have a benefit. Join host, Geoff Wall, as he reviews a randomized controlled study from Mexico on this novel strategy.   The GameChanger Methylene blue is a specific inhibitor of the inducible nitric oxide synthase for indirect pressor effects. Despite confounders, this smal...

The proverbial ‘pill’ or hormonal contraception may be available over-the-counter (or at least a progestin-only version) by year’s end. Join guest host, Jake Galdo, as he discusses improved access to care with Erin Raney as the FDA debates over-the-counter status for hormonal contraceptives. The GameChanger Women’s health is a priority area from a public health perspective – the US has lots of roo...

Sexually transmitted infection (STI) risk in high risk patients is a common problem compounded by antimicrobial resistance. Join host, Geoff Wall, with guest Amanda Bushman, as they discuss a new post-exposure prophylaxis (PEP) therapy for STI prevention   The GameChanger Sexually transmitted infection incidence is higher than most clinicians suspect. Doxycycline may offer effective post-exposure...

While we all know students who may exhibit more confidence that they have the right to based on their actual knowledge and experience, more often as preceptors we have students who demonstrate a lack of confidence that gets in the way of their learning. It is easy to make assumptions about why a student demonstrates a lack of confidence, but often we have missed the mark. By understanding the root...

About 50% of Americans have hypertension, yet WHICH is a preferred anti-hypertensive strategy is a random process. And pharmacogenomics may not be needed. Join host, Geoff Wall, as he evaluates a recent study evaluating the role of personalized medication selection for persons with hypertension.   The GameChanger Although no genetic markers exist to determine optimal hypertensive pharmacotherapy,...

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 2 of a two-part series examining new research on the proposed RSV vaccine.   The GameChanger RSV, COVID-19, and influenza are major disease burdens on children and older...

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 1 of a two-part series examining new research on the proposed RSV vaccine. The GameChanger RSV, COVID-19, and influenza are major disease burdens on children and older ad...

Community Acquired Pneumonia (CAP) has a high mortality rate. A new study evaluates the use of hydrocortisone for severe CAP in the ICU setting. Join host, Geoff Wall, as he evaluates if the evidence stacks up. The GameChanger The use of steroids to treat severe pneumonia has waxed and waned for many years with insufficient evidence. A recent study found steroids improved a number of outcomes, inc...

Co-precepting can help with workload while providing a diverse experience for learners, but it is not without its challenges. Listen in to weigh the pros and cons while gathering some strategies to ensure success if you plan to consider, or are currently, co-precepting with a colleague. Kate Newman is the Director of Experiential Education at Southern Illinois University Edwardsville School of Pha...

Several studies have found the improved outcomes and quality of life through deprescribing. However, it rarely happens. Join host, Geoff Wall, with guest, Kristin Meyer, as they evaluate a new studying looking at pharmacist-provided describing services during transition of care. The GameChanger Older patients are on numerous medications often with limited therapeutic benefit and high risk of adver...

ICU patients are at high risk for venous thromboembolism, and the majority of patients require prophylaxis. The challenging therapy is thrombocytopenia. Join host Geoff Wall, as he evaluates the results of a new study evaluating the clinical thresholds for chemical prophylaxis. The GameChanger The majority of ICU patients eligible for VTE prophylaxis do not receive it. Different clinicians use dif...

The Updated AAAAI Guidelines on Drug Allergies Drug allergies are a common challenge for all prescribers, patients, and pharmacies. They are associated with increased costs, adverse effects, and extended hospitalizations. Join host Geoff Wall as he reviews the newly released AAAI guidelines on drug allergies. The GameChanger Over 90% of patients claiming a penicillin allergy are not allergic. Sulf...

Although the numbers may be low, COVID-19 and other illnesses remain a significant threat to patients. The role of masks in preventing SARS-CoV-2 spread has been politicized since the beginning. A new meta-analysis purports to answer the question of mask effectiveness. Join host Geoff Wall, with guest Jake Galdo, as they deep dive into the article and evaluate the science. The GameChanger A new me...

Pharmacogenomics have long held the promise of using personalized information for drug selection to maximize efficacy and minimize adverse reactions. A new study evaluates the routine use of pharmacogenomic testing to improve safety in a wide range of medications. Join host, Geoff Wall, as he evaluates personalized medicine. The GameChanger Most studies using routine pharmacogenomic testing in cli...

Pharmacy learners - IPPE, APPE, Residents - may not always be forthcoming with honest feedback. But they know what they appreciate (or don't) in a learning experience. As a preceptor, your approach to teaching has a huge impact on student learning. We asked two 4th year pharmacy learners to share what matters most to them in a preceptor. Their answers may surprise you! Listen in to learn what...

For the past two decades, large amounts of isotonic fluids have been the first step in treating septic shock despite adverse events of fluid overload, coagulopathy, and pulmonary edema. A new NIH study evaluates this strategy. Join host, Geoff Wall, with guest, Matt Trump, DO, as they evaluate initial septic shock management. The GameChanger Liberal fluid management (30 mL/Kg) in the early phase o...

Every January, the American Diabetes Association publishes the Standards of Care in Diabetes. The guidelines are a living document and change throughout the year; however, the January update is the seminal changes for the entire document. Join host, Geoff Wall, with guest, Jake Galdo, as they discuss what’s new and great in the guidelines. The GameChanger In addition to medication recommendations,...

Furosemide is the most prescribed loop diuretic for heart failure; however, furosemide’s pharmacokinetic parameters are less than ideal compared to other loop diuretics. Join host, Geoff Wall, as he evaluates the first randomized controlled trial comparing loop diuretics in heart failure. The GameChanger Torsemide has potential pharmacokinetic advantages compared to furosemide in the treatment of...