Big Questions with Cal Fussman

A high school student named Matteo Paz uses old NASA data and new AI to find 1.5 million objects never noticed before in space (including planets in other solar systems). AI can now predict 130 diseases (including heart ailments, kidney failure and strokes) based on studying one night of sleep. And a school called Alpha uses only AI tutors, teaches core academics for only two hours a day and achie...

In the age of artificial intelligence, it isn't a machine that stops Cal in his tracks—it's a deeply human idea. What if playing a video game could help fight cancer? Thanks to Travis Jennings and a small group of friends, a chain reaction begins—turning gamers with little money of their own into philanthropists. A breakout company called Besitos matches their winnings with donations to the Americ...

Imagine a mind that can solve a Rubik's Cube in 17 seconds. A mind that contributed to the development of OpenAI. A mind that directed AI for Elon Musk at Tesla. A mind named one of Time Magazine's Top 100 in artificial intelligence. Now imagine that same mind encountering recent, almost "alien" advances in programming—so startling they prompted a public admission: "I have never felt so behind. "...

When Cal visits an old mentor, he's struck by two realizations. First: Some of the most profound moments in a young person's life can happen in entry-level jobs, when the right person takes you in, opens a door, and points you on the right path. Second: As artificial intelligence wipes out many of those first jobs, it will also erase those connections and moments. What disappears isn't just work....

There are those believe artificial intelligence will cure cancer, reverse global warming , and unlock human potential. There are others who believe it will end everything we know. For the first time in history, both sides may be right. We are living inside the most consequential argument humanity has ever had — and the clock is ticking .

When Cal returns to Tampa's Ybor City to speak, he keeps a ritual that's become almost sacred: a meal at the legendary 120-year-old Columbia Restaurant, followed by a quiet moment of thanks to the man who first sent him there — Muhammad Ali's doctor, the renowned Ferdie Pacheco. Ferdie wasn't just the "Fight Doctor." He was an artist, a storyteller, and a man with a taste for a good practical joke...

The future may not be hiding in Silicon Valley. It could be hidden in your childhood. When a bright young grad sits down at Cal's Thanksgiving table worried about AI layoffs and disappearing careers, Cal offers an unexpected roadmap: Don't try to predict the future . . . remember it. Some of the greatest innovators didn't choose their path — their childhood chose it for them. In this episode, Cal...

Here is a question Cal never thought he'd ask. Let's just say a human marries an AI and they get divorced. Does ChatGPT get the alimony? This is the way we need to begin thinking after news came out that a Japanese woman married an AI bot. Buckle your seatbelts. It's the groundswell of statistics on the romantic mingling between humans and AI that will raise your eyebrows to the middle of your for...

When Cal looks back on his life, he sees a relentless drive that's guided him to his 69th birthday: Never be bored. His past reveals a simple truth. Boredom ends where curiosity begins.

Cal looks over a bountiful breakfast menu and remembers the statistics he heard about kids going hungry in Tampa Bay — a city that, through his traveler's eyes, appears to be flourishing. When you hear the numbers, you'll understand how giving just a little can make this your best Thanksgiving ever.

When Kobe Bryant watched the Eagles win Super Bowl 52 on television, he wasn't alone — he was holding his 1-year-old daughter, Bianka, in his arms. That moment, captured on home video, wasn't just about football. It was about the way a team becomes a language between generations. Rewatching that clip sends Cal into a reflection of his own: the passion for sporting events his father passed on to hi...

After actress and author Suzanne Somers passed away, her husband couldn't let go — so he brought her back. Not in memory. But as an AI twin. He created a life-like humanoid to converse with in her voice and keep her spirit alive. When Cal hears the story, questions linger: Is this a way to deal with grief? Or is it evolution? And are there advantages to passing on the lessons and wisdom of a life...

Everything An unexpected e-mail sends Cal spiraling back to a conversation with the actor Johnny Depp — and to Ernest Hemingway's brush with death in back-to-back plane crashes. When Cal opens a book titled What Do You Want to Do Before You Die? he encounters a question that awakens our wildest dreams and forces us to look in the mirror.

A police van that drives itself, launches drones, reads license plates, and streams live infrared video straight to headquarters. Miami-Dade just unveiled it. A cruiser with no cops inside. Cal explores the next wave of law enforcement: part innovation, part surveillance. It's the kind of technology that makes some people uneasy — but after learning that 1 in 93 Americans die in traffic accidents,...

In a week when companies propose growing human eggs from male skin and gestating babies inside robots, OpenAI CEO Sam Altman is seen in a viral video shoplifting at Target — bringing laugher to some and raising a chilling question to others: what if we can no longer trust our eyes? We're entering a moment where biotech, AI, and deepfakes collide — and our sense of reality begins to blur. Cal asks:...

Roughly 1 in 93 Americans will die in a car accident. According to the National Safety Council, that's the math—even after seatbelts, airbags, sensors, and the smartest cars we've ever built. Cal found that out the hard way, after being rear-ended by a cement truck on a Connecticut highway. The crash led him to uncover not just some shocking statistics, but also a simple, overlooked way we can fig...

Cal comes upon a book called The Fourth Turning Is Here which suggests that we're in a historical cycle of crisis when institutions collapse and a new world order emerges. Then he walks through the natural institution known as Central Park and sees a world view that couldn't be better. A short message to think about . . .

Two dates. Separated by decades. Bound by a thread we'd all prefer didn't exist. Cal revisits the first—a day etched in memory that too many now treat as common behavior. He weighs the second—fresh in the headlines, heavy in the heart—and wonders if it's a shadow of what lies ahead. The connections aren't obvious. They aren't supposed to be. But once you hear them, you won't forget.

Raveling passed away early this month at 88 after living a life shaped by being in the right place at the right time — and knowing what to do when he got there. As a boy, after losing his father and seeing his mother institutionalized, he found stability at a Catholic boarding school. That path led him to become the first African-American basketball player at Villanova … to meet coaching legend Bo...

Billie Eilish was just 13 when she recorded the song Ocean Eyes in the bedroom of her home and her brother Finneas uploaded it to SoundCloud. Within weeks, hundreds of thousands had listened to it. That's how one haunting voice changed pop forever. Now, Cal's friend Phillip is a finalist for SoundCloud's Tomorrow's Breakthrough Artist Award. He's not the next Billie — he's the first Phillip. And h...

Cal was ready to dump his storage bins of CDs, tape cassettes, and DVDs — until he discovered a twist: the world is racing back to the very things he was about to throw away. Parents are pulling out old DVD players so their kids can choose movies without being spoon-fed by algorithms. Taylor Swift just announced her next album will also drop on cassette. And suddenly "Old School Cal" looks like he...

Cal sits down with Jeff Burningham, author of The Last Book Written by a Human, to unpack the AI tidal wave about to hit classrooms, boardrooms, governments, and even religions. This isn't doomscrolling—it's a positive roadmap through the disruption ahead. If you want to become wise in the age of AI, start here.

The NFL passed on Shedeur Sanders — son of Deion "Prime Time" Sanders — through the first four rounds of its 2025 draft, despite the quarterback's two electric seasons in college with Heisman trophy winner Travis Hunter. It felt eerily like the way algorithms reject qualified people in the job market. Shedeur's notoriety and connections got him a shot . . . and his exhibition season debut with the...

Jim Carrey's $10 Million Lesson  Cal has an epiphany as he's giving one of his storytelling workshops. He's able to tie the thought to the moment in 1985 when a down and out actor named Jim Carrey wrote a check to himself for $10 million to be cashed 10 years later when he became a film star. The $10 million did come to Carrey ten years later with the release of the hit Dumb and Dumber. Cal wonder...

On a sunny Sunday morning, Cal shares breakfast with friends—when a woman reveals how a shady third-party travel site jacked up her airline ticket price. It was no fluke: The company is flooded with complaints on Yelp. The story sparks a deeper question in Cal: what's happened to trust in our time? That question is answered by billionaire investor Mark Cuban: "In three years, AI will flood us with...