University of Chicago Podcast Network

Big Brains

Science EN ↓ 223 episodes

Big Brains explores the groundbreaking research and discoveries that are changing our world. In each episode, we talk to leading experts and unpack their work in straightforward terms. Interesting conversations that cover a gamut of topics from how music affects our brains to what happens after we die.

Author

University of Chicago Podcast Network

Category

Science

Podcast website

big-brains.simplecast.com

Latest episode

Jul 9, 2026

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Episodes

How Homeownership Shaped Race In America, with Adrienne Brown 22.08.2024

Race has played a huge role in the creation of mass homeownership in the United States. Discriminatory housing practices including redlining, exclusionary zoning and whitewashing led to great disparities in home ownership among White and Black homeowners. Despite the passage of the Fair Housing Act in 1968, the damage had been done to communities of color and the rates of Black homeownership. Mass...

Fighting Back Against AI Piracy, with Ben Zhao and Heather Zheng 08.08.2024

If you’ve spent any time playing with modern AI image generators, it can seem like an almost magical experience; but the truth is these programs are more like a magic trick than magic. Without the human-generated art of hundreds of thousands of people, these programs wouldn’t work. But those artists are not getting compensated, in fact many of them are being put out of business by the very program...

The Bioelectric Future of Regenerative Medicine 25.07.2024

In the near future, birth defects, traumatic injuries, limb loss and perhaps even cancer could be cured through bioelectricity—electrical signals that communicate to our cells how to rebuild themselves. This innovative idea has been tested on flatworms and frogs by biologist Michael Levin, whose research investigates how bioelectricity provides the blueprint for how our bodies are built—and how it...

Is Mindfulness The Secret To Health? 11.07.2024

Can you heal faster just by tricking your brain? Could you lose weight with only a change of mindset? Could you think yourself into being younger? If you think the answer to all these questions is no, you haven’t read the research from renowned Harvard University psychologist Ellen Langer. Our podcast is taking a quick summer break, but we wanted to take this time to share some of our favorite epi...

Feeling Stuck? Here’s How To Achieve a Breakthrough, with Adam Alter 27.06.2024

We've all been stuck at some point in our lives — whether we've been stuck at a job and wanting to make a career change, stuck in a location and wanting to move somewhere new, or stuck in relationships or friendships. But the method to getting “unstuck” and achieving a breakthrough might be easier than you think. Using research-backed tools, New York University's Adam Alter shares his tips for how...

What Makes Something Memorable (or Forgettable?) with Wilma Bainbridge 13.06.2024

There is a science to what we remember and what we don't. For instance, why do we remember certain pieces of artwork, some brands’ logos, or even people's faces? University of Chicago psychologist Wilma Bainbridge has been studying what makes things memorable for over a decade. Through her research, she has found that there is a common thread about what most people remember—and even what we rememb...

Learning To Speak To Whales Using AI, with David Gruber 30.05.2024

If aliens landed on Earth tomorrow, how would we talk with them? Well, we already have a kind of creature on this planet we could attempt to talk to first, and in the last few years a team of renowned scientists have been exploring the ocean studying sperm whales to get that conversation going. David Gruber is a professor of biology and environmental science at CUNY and the founder of  Project CET...

Storm Warning: Why Hurricanes Are Growing Beyond Measure, with Michael Wehner 16.05.2024

We all know that extreme weather events like hurricanes are getting worse due to climate change, but what scientists would really like to know is: By how much worse exactly? This year a team of researchers argued that hurricanes have become so much more extreme due to climate change that we need to add a new category 6 to the Saffir-Simpson scale, which measures the wind speed of hurricanes. One o...

How To Manifest Your Future Using Neuroscience, with James Doty 02.05.2024

We've all heard the phrase "Manifest Your Destiny" when it comes to wanting that new promotion, figuring out a new career path or just trying to achieve that long-term goal. It turns out that the act of manifestation is not merely pseudoscience—it actually has a body of research in neuroscience to back it up. Dr. James Doty has been exploring this topic throughout his career; and offers scientific...

Why We Die—And How We Can Live Longer, with Nobel Laureate Venki Ramakrishnan 18.04.2024

They’re perhaps the oldest questions in the science: Why do we die? And could we find a way to live forever? But for decades, anti-aging research was a “backwater” of the scientific community, consider too fanciful and unrealistic. That is until the last few years. Modern advances in biology have taught us a lot about how we age and why we die—could that knowledge help us turn back the clock? In h...

What Dogs Are Teaching Us About Aging, with Daniel Promislow 04.04.2024

Every dog owner has faced the hard realization that their dog won’t live as long as they do, but we’ve all probably wondered: Why do some dogs live longer than others? It turns out that several factors are at play, according to the largest research study of dogs, known as The Dog Aging Project. Prof. Daniel Promislow of the University of Washington is co-director of the project, which examines how...

Where Has Alzheimer’s Research Gone Wrong? with Karl Herrup 21.03.2024

For more than a century, scientists have been studying Alzheimer’s disease and developing theories about its underlying cause. The leading theory for decades has been that abnormal amyloid plaques in the brains of those who suffer from the disease are the central cause. But, according one renowned Alzheimer’s researcher, this myopic focus is not only flawed, but may be holding back our search for...

Why Breeding Millions of Mosquitoes Could Help Save Lives, With Scott O'Neill 07.03.2024

Mosquito-borne diseases are one of the greatest global health threats, infecting around 700 million people every year with Zika virus, dengue fever, malaria and yellow fever — which can all be deadly if left untreated. Unfortunately, the mosquito population is not slowing down, and factors like climate change and increased global travel are broadening the mosquito's range. The effort to stop the m...

Why Shaming Other Countries Often Backfires, with Rochelle Terman 22.02.2024

How do you stop a government from continuing to commit human rights abuses? You could take them to an international court of justice, or file a complaint at the UN. But none of those bodies have any enforcement power. Short of going to war, the only option on the table in most international situations is to name and shame. But is that strategy effective? In her new book, “ The Geopolitics of Shami...

Can Trump Legally Be President?, with William Baude 06.02.2024

The Supreme Court’s decision on whether Colorado can take former President Donald Trump off the ballot in the 2024 election may be one of the most consequential in its history. The case will turn on the court’s interpretation of Amendment 14, Section 3 of the Constitution, which bars any previous elected official from holding office if they participated in an insurrection. When making their case,...

What Our Hand Gestures Reveal About Our Thoughts, with Susan Goldin-Meadow 25.01.2024

Language shapes our world. But when we speak, there is actually a secret conversation happening beyond our words. It’s happening not with our mouths—but with our hands. Prof. Susan Goldin-Meadow is a distinguished scholar of psychology at the University of Chicago. Her research into deaf children who were never taught sign language led her to studying why the gestures we do all day may contain mor...

Psychedelics Without Hallucinations: A New Mental Health Treatment? with David E. Olson 11.01.2024

The United States is facing a real mental health crisis. In the last few years, one possible treatment has gotten a lot of press: psychedelic drugs. But what is actually happening in a person’s brain when they take a psychedelic? Could understanding the biology and the chemistry allow us to make better and safer versions of these drugs—and maybe even create psychedelics without the hallucinations?...

The Science Of Happiness 28.12.2023

The Big Brains team is taking some time off during the holidays but for all those travelers out there heading home, we wanted to make sure you still had your favorite podcast in your feed. So, we’re resharing one of our most popular episodes ever. It’s about the science of happiness. What is the key to living a happy and fulfilling life? The answer is actually quite simple, according to the two sc...

Do We Really Have Free Will? With Robert Sapolsky 14.12.2023

Here’s the question you’re going to be asking for the next 30 minutes: Did I freely choose to listen to this podcast, or did I actually have no choice at all? Most of us probably believe we have free will. We feel like we make decisions, and that each of us is responsible for the consequences of our actions. But what if that’s all just an illusion? Robert Sapolsky is a renowned professor of biolog...

A Radical Solution To Address Climate Change, with David Keith 30.11.2023

Climate change can feel like an impossible crisis these days. Every week there is some new report about the irreversible damage we’re doing to our planet and the havoc it will bring to people’s lives. We all know cutting emissions is the solution, yet governments and companies seem no closer to meeting the goals that scientists say we must hit. It can feel hopeless. There is one possible controver...

How PFAS “Forever Chemicals” Are Harming Our Health, with Linda Birnbaum 16.11.2023

By now, you've probably heard about the dangers of PFAS “forever chemicals.” These chemicals are all around us—they're in waterproof hiking boots, electronics, nonstick pans and even our drinking water—but there's no way for them to break down in our environment. Epidemiological studies have linked to these chemicals to numerous diseases—from kidney cancer, liver cancer, obesity, decreased fertili...

Are We Worse People Than We Used To Be? With Adam Mastroianni 02.11.2023

How many times have you heard this phrase: “Back in the day, people were nicer” or “People aren’t as kind as they used to be?” Most of us have experienced the feeling that people are becoming meaner over time, year after year. But is it true? Are people really less kind than they used to be? That’s the question that has bothered psychologist Adam Mastroianni most of his life. He set out to find an...

Freakonomics’ Steven Levitt On The Secret To Making Tough Choices 19.10.2023

Of the academic books that have become household names, “Freakonomics” must be at the top of the list. The 2005 book by University of Chicago scholar Steven Levitt and journalist Stephen Dubner created not only a whole new way of thinking about discovering answers to complex problems, but launched a media empire—from book sequel to a movie to a hit podcast. On this special episode, we sat down wit...

Will Political Violence Destroy Our Democracy?, With Robert Pape 05.10.2023

Since the Jan. 6, 2021 attack on the U.S. Capitol, University of Chicago Prof. Robert Pape has been closely observing the threats to our democracy. Now, the renowned terrorism expert says that violent ideas coming from a dedicated minority are moving from fringe to mainstream. In 2021, Pape's team along with NORC at the University of Chicago launched the Dangers to Democracy tracker, an ongoing se...

Defending Campus Free Speech In A Polarized Age, with Paul Alivisatos and Tom Ginsburg 22.09.2023

Free speech is probably one of the most polarizing public topics of debate. And those arguments only become more intense when it comes to free expression on college and university campuses. Should professors be allowed to say whatever they want? What about speakers being invited to campus? Who gets to say what is acceptable and unacceptable? The University of Chicago has had a unique and long hist...

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