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Adopting an engineering mindset will help the field focus its research priorities.

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neuroscience research much-needed international visibility.

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions.

The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.

Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.

With an eye toward realism, the neuroscientist, who has a new study about bats out today, creates microcosms of the natural world to understand animal behavior.

Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.

Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.

A protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

A researcher’s theory hangs muscle degeneration on a broken neural circuit.

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.

The mapping, which traces how the central nervous system interacts with the rest of the body, challenges the idea that behavior control is centralized.

The traditional mechanistic framework must give way to a richer understanding of how brains actually generate behavior over time.

Concerns include the administration’s reliance on weak, correlational evidence rather than established research.

Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.

The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.

The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for sensing the world and coordinating movement.

These partnerships accelerate neuroscience by enabling researchers to share resources and expertise, as well as generate more relevant and reproducible results. But new federal funding restrictions in the United States are putting such collaborations in jeopardy.

The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.