American Journal of Psychiatry Audio

This month, Deputy Editor Susan K. Schultz, M.D., discusses psychiatric symptoms in Wilson's disease, interactions between inflammation and depression, circulating miRNA levels in schizophrenia, the relation of smoking status to later schizophrenia, development of posttraumatic stress disorder in Army servicemembers following traumatic brain injury, and working in the Amish culture. Articles may b...

This audio program explores the role of ketamine and other NMDA antagonists as treatments for depression, and a replication study of a gene-environment interaction affecting depression risk. A study lasting four decades looked at whether ADHD in adults is a childhood-onset disorder, and another longitudinal study followed up adolescents at clinical high risk of psychosis, to see how many of them a...

This audio program features a discussion of differential diagnosis of frontotemporal dementia, autoimmune encephalitis in postpartum psychosis, the role of oxytocin in borderline personality disorder, neural correlates of error processing in young people exposed to severe childhood abuse, light therapy versus cognitive-behavioral therapy for seasonal affective disorder, and cognitive enhancement t...

This audio program includes a discussion of the role of the psychiatrist in the collaborative care model, pharmacological management of Lewy body dementia, the relationship of depression subtype to antidepressant response, amygdala activity at rest in paranoid individuals with schizophrenia, and the use of clonidine in opioid abstinence to prolong abstinence and decouple stress from craving in dai...

This audio program explores the diagnostic precursors of bipolar disorder in offspring of bipolar parents, as well as a study examining the intergenerational transmission of anxiety, by looking at the children of twins, and another focusing on separation anxiety disorder in children and adults. Various diagnoses are characterized by impaired response inhibition, and a study is presented of how it...

This audio program features a discussion on a pair of research articles on teenage drinking and on a review article on cognitive-behavioral therapy for anxiety disorders in adolescents. There also is discussion regarding psychiatric care during hepatitis C treatment with direct-acting antivirals, the effects of clozapine on working memory, and the combination of citalopram and methylphenidate for...

This audio program presents a discussion of diagnostic and clinical challenges of narcissistic personality disorder and of two clinical trials of psychotherapy. One examined interpersonal psychotherapy for PTSD, and the other tested the use of brief cognitive-behavioral therapy to reduce suicide attempts in military personnel with a previous history. An additional article compared the effects of d...

This audio program includes a discussion of a study that used an algorithm to search electronic health records for clinical information relevant to the Research Domain Criteria; an article on predicting the transition from mild cognitive impairment to dementia; a trial on reducing reactivity to alcohol cues in patients with alcohol dependence; a study of the relationship between C-reactive protein...

This audio program includes a discussion of adjustment disorder in a health care worker with Ebola, a case of psychotic symptoms that improved with a gluten-free diet, medication prescribing for first-episode schizophrenia, outcomes for young people at ultra-high risk for psychosis who do not transition to psychotic disorders, possible mechanisms in perimenopausal depression, and change during ado...

This audio program includes a study of postpartum psychosis and mania, a home-visiting intervention for pregnant teenage American Indian mothers, brain patterns underlying learning deficits in autism spectrum disorders, the clusters of genetic variants and clinical features of schizophrenia, the Affordable Care Act and its expansion of insurance for young adults. Articles can be viewed online at a...

This audio program includes a discussion of hypercalcemia and hyperparathyroidism during lithium therapy. It also examines ECT for treatment-resistant bipolar depression and for clozapine-resistant schizophrenia; a weight loss intervention for individuals taking antipsychotic medications; an intervention for kindergartners with chronic conduct problems; a clinical trial offering depression care in...

This audio program includes a discussion of mercury poisoning and its neuropsychiatric presentations and presents a large study that used a new approach to testing the effect of antidepressants on heart rate. Several articles are about biomarkers of psychiatric illness: one identified a combined epigenetic and genetic biomarker for suicide, and another found that a measure of inflammation in depre...

This audio program explores pulmonary embolism in psychiatric patients, a trial of smoking cessation combining varenicline and bupropion, a trial comparing quetiapine with placebo for treatment of borderline personality disorder, a study of positive traits in co-twins of patients with bipolar disorder, a study evaluating the genetic and environmental contributions to familial recurrence of autism...

This audio program explores relapse prevention in pediatric depression and the risk of mania or hypomania for patients with bipolar depression taking an antidepressant without a mood stabilizer. The series on global mental health describes a man in Cambodia with seizures, anorexia, and depression. The issue covers adverse neuropsychiatric effects of glucocorticoid medications, the patient-therapis...

This audio program presents diagnostic and treatment aspects of disruptive mood dysregulation disorder, predictors of long-term outcome in youths with bipolar disorder, reading ability and elements of impulsivity related to aggression in schizophrenia, a global health review of a woman in Uganda with HIV and major depression, and the connection between schizophrenia and maternal levels of C-reacti...

This audio program presents a case of delirium with manic symptoms in a patient with end-stage COPD, a clinical vignette about a chronically depressed woman in Iran, low dopamine transmission in the prefrontal cortex of people with alcoholism, a test of mindfulness training as a way to increase resilience in Marines before deployment, the influences of maternal and paternal PTSD on epigenetic regu...

This audio program discusses a new tool for screening military veterans to evaluate the risk of violence. One article reviews the care of pregnant women with ADHD, and another one reports on outcomes after in-utero exposure to lithium. Also discussed is the treatment of separation, generalized, and social anxiety disorders in children and adolescents, and two longitudinal studies shed light on the...

This audio program discusses DSM-5 classification of anxiety and related disorders, antipsychotic use in breast cancer patients, and adult outcomes of disruptive mood dysregulation disorder. Treatment trials for a parental intervention aimed at preventing antisocial personality and family-focused treatment plus medication for adolescents with bipolar disorder are also examined. The issue also look...

This audio program begins with a new section, Perspectives in Global Mental Health, featuring cultural aspects of depression and ideas for global dissemination of psychological treatments. The issue also examines psychological interventions for psychosis, cognitive training, dietary coaching for elderly persons with subsyndromal depressive symptoms, psychiatric symptoms as risk factors for mild co...

This audio program offers a commentary on the Research Domain Criteria project by the Director of NIMH. In addition, it reviews liver injury due to antidepressants, head injury as a risk factor for psychiatric disorders, whether women and men differ in the etiology of depression, the effect of cannabis on working memory in adolescent monkeys, whether a genetic polymorphism affected topiramate's ef...

This audio program examines lurasidone treatment of bipolar depression, both as monotherapy and as an adjunct; psychotherapy for bipolar depression related to comorbid anxiety disorders; a computerized method for rating anxiety; genetic, family, and community risk factors for drug abuse; the risk of autoimmune diseases in individuals with a personal or family history of schizophrenia or related ps...

This audio program examines the risk of upper gastrointestinal bleeding with short-term use of SSRIs and schizophrenia complicated by hepatitis C and hepatic encephalopathy. It also reports results from a study in which neuropsychological functioning was tracked from childhood to age 38, a study comparing psychoanalytic psychotherapy and CBT for bulimia nervosa, a review of the relation of childho...

This audio program includes a case of folie à deux and infanticide, the DSM-5 changes in sleep disorder classification, and new research on ketamine for treatment-resistant depression. Two reports explore brain structure and functioning in patients with eating disorders. Additional studies examine neural mechanisms of frustration in chronically irritable children and the role of oxytocin in mental...

This audio program examines relationships between violence and mental illness. This issue looks at psychiatric characteristics of homicide defendants, differences in mental illness between gang members and other men with violent behavior, and aggression in a child with Asperger's disorder. It also features a study of the relationship between firearms availability and suicide risk, a trial of prazo...

This audio program contains articles on the behavioral treatment of insomnia in bipolar disorder, the relation of childhood trauma to psychotic experiences, comparing psychodynamic therapy and cognitive-behavioral therapy (CBT) for social anxiety disorder, augmenting antidepressant treatment with CBT for generalized anxiety disorder in older adults, and late-onset agoraphobia in a population study...