Big Picture Science

The worry about whether H5N1 will trigger a human pandemic has concealed a startling reality. Avian influenza has already taken an enormous toll on the lives of other animals. Since 2005, the number of wild and domesticated birds killed is greater than the combined human populations of the United States and Russia. Bird flu is burning through wild flocks, poultry farms, and mammal populations, inc...

The idea that the universe is made of tiny vibrating strings was once the science theory du jour. String theory promised to unite the disparate theories describing particles and gravity, and many people, not just scientists, were optimistic that a theory of everything might be within our grasp. But here we are, many years later, and string theory doesn’t seem to have delivered on its initial promi...

In Brazil, leaders from across the globe are gathering for COP30, the premier climate summit in the world. For the first time, the U.S. is sitting it out, after exiting the Paris Agreement. There is, however, a ray of hope in the global efforts to reduce fossil fuel emissions. Bill McKibben, an environmentalist and journalist who describes himself as a “professional bummer-out-of-people,” has good...

“The Mississippi River will always have its own way; no engineering skill can persuade it to do otherwise,” said Mark Twain. In this, our final episode marking the 20th anniversary of Hurricane Katrina, we consider how efforts to control the Mighty Mississippi – a river engineered from its Minnesota headwaters to its Gulf Coast outlet – have responded to the devastating storm, and how New Orleans’...

What happens to us after we die is as much a question for anthropology and ecology as it is for theology.  Death and decay are not comfortable subjects, but some scientists study them unflinchingly, knowing that doing so yields valuable scientific insights about decomposition. We hear about The Body Farm at the University of Tennessee, Knoxville where forensic anthropologists dissect how variables...

Shipwrecks are scenes of tragedy, but they are also bits of history frozen in time that can provide insights into events and ideas from long ago. That is, if we can find them.  From an 11th century Viking sailing ship to a WW II era British cargo ship with a mailbag of letters onboard amazingly preserved, an underwater archeologist takes us on a deep dive into history. Guest: David Gibbins - under...

Long before Orson Welles provoked a panic with his 1938 radio broadcast of a Martian invasion in War of the Worlds, we were fascinated with the possibility of life on the Red Planet. We may be a step closer to finding it after the Perseverance rover turned up tantalizing evidence of possible ancient life in the form of mineral deposits in a Martian rock. But to be sure, we need to test that rock s...

The tiny bean-shaped structures in your cells – mitochondria – are little powerhouses. Recent research suggests they may unlock overall good health, or, when they fail, cause diseases such as diabetes and Alzheimer’s. How strong is the science for these claims and what, if anything, should we be doing to improve our mitochondrial health? Should we take a cue from influencers who suggest drinking a...

We’re hurtling towards a post-antibiotic world, as the overuse of antibiotics has given rise to dangerous drug-resistant bacteria. Can we fight back using viruses as weapons? An obscure medical therapy uses certain viruses called bacteriophages to treat infection. For a century attempts to turn phage-therapy into a life-saving treatment have faltered, but today there’s renewed interest in this app...

Strapped-on brass noses, frog skin grafts, human organs grown in pigs: The world of replaceable body parts is both amazing and a bit unsettling. But who better give us a tour of the past and present of what medical engineering considers Plan B, than the inimitable science writer Mary Roach. Guest: Mary Roach – Science writer and author of “Replaceable You: Adventures in Human Anatomy” Featuring mu...

As their name suggests, “forever chemicals” have extraordinary staying power. When these nearly indestructible compounds find their way into our soil and water, they don’t break down for hundreds or thousands of years. PFAS – the name for these synthetic chemicals – isn’t just in our natural environment. Scientists have found it everywhere, including in the blood of nearly every living being.  In...

Have scientists discovered an alphabet in whale calls? As researchers try to decipher the series of clicks made by sperm whales, we ask whether these cetaceans might have language, and if it follows that whales are thinking animals too. Could we one day get a peek into the thoughts of a humpback whale? Meanwhile, somewhere along the long path of evolution, one species emerged with an impressive gi...

We are closer than ever to finding aliens according to astrophysicist Adam Frank. He isn’t alone in his optimism. Over the last two decades, the tools used to search for extraterrestrials have been advancing mightily. Where we were once only monitoring with radio telescopes, we are now actively looking for bio and technosignatures on exoplanets. Find out why scientists think new technology may be...

A canopy of stars in the night sky is more than breathtaking. Starlight is also an important tool that astronomers use to study our universe. But the growth of artificial light and light pollution are creating dramatic changes to the nighttime environment. Let your eyes adjust to the dark as we travel to a dark sky reserve to gaze upon an increasingly rare view of the Milky Way and explore what we...

“The Mississippi River will always have its own way; no engineering skill can persuade it to do otherwise,” said Mark Twain. In this, our final episode marking the 20th anniversary of Hurricane Katrina, we consider how efforts to control the Mighty Mississippi – a river engineered from its Minnesota headwaters to its Gulf Coast outlet – have responded to the devastating storm, and how New Orleans’...

Ever heard of a beauty quark? How about a glueball? Physics is full of weird particles that leave many of us scratching our heads. But these tiny particles make up everything in the quantum world and in us and are the basis of the fundamental scientific theory called The Standard Model. But it doesn’t explain everything. It can’t account for dark matter or dark energy, for example. We find out whe...

Telescopes are like light buckets. The bigger the telescope, the more light collected for astronomers to observe. With recent advances in technology, amateur astronomers can join professionals for a chance to observe stellar nurseries and exoplanets many light-years away. But as our capabilities increase, so do the mysteries, including those around high-energy bursts coming from an otherwise unrem...

They are known for holding branches in their paws and gnawing on them like corn cobs. They build lodges and dams which occasionally flood roads. Cute, comical, and considered pests, beavers were nearly hunted to extinction for their pelts before conservation efforts allowed their populations to rebound. Now environmentalists and engineers are reintroducing North America’s largest rodent to drought...

Has children’s play become too safe? Research suggests that efforts to prioritize safety harms children’s mental and physical development during play and contribute to anxiety. One solution: introduce risk into play. We visit an adventure playground where kids play unsupervised with anything from scraps of metal to hammers and nails. Plus, what are the evolutionary benefits of play? After all, we’...

How frequently do you think about fasteners like screws and bolts? Probably not very often. But some of them a storied history, dating back to Egypt in the 3rd century BC. They aren’t just ancient history. They help hold up our bridges and homes today. Join us as we dissect a handful of engineering inventions that keep our world spinning and intact. Guests: Roma Agrawal - structural engineer and a...

Drinking a cup of coffee is how billions of people wake up every morning. But climate change is threatening this popular beverage. Over 60% of the world’s coffee species are at risk of extinction. Scientists are searching for solutions, including hunting for wild, forgotten coffee species that are more resilient to our shifting climate. Find out how the chemistry of coffee can help us brew coffee...

What physical activity gives you joy? Whether it’s walking, running, dancing or swimming, your body evolved to do it. We are made for movement. But there’s a cost, as anyone with a sore neck or aching back knows. From the tiny muscles in our skin, which raise the hair on our arms, to the intricate mix of bone, blood vessels, and nerves in our neck, natural selection has struck a delicate and somet...

Healthy rivers and riparian ecosystems are teaming with life, but should rivers themselves be considered alive? The question is central to the growing rights-of-nature movement that claims that ecosystems and entities, like rivers, have legal rights. After Ecuador enshrined the rights of nature in its constitution, lawyers employed the new personhood status to stop mining companies from clearing a...

The discovery of a massive amount of lithium under the Salton Sea could make the U.S. lithium independent. The metal is key for batteries in electric vehicles and solar panels. But the area is also a delicate ecosystem. We go to southern California to hear what hangs in the balance of the ballooning lithium industry, and also how we extract other crucial substances  – such as sand, copper and iron...

Whales are aliens on Earth; intelligent beings who have skills for complex problem-solving and their own language. Now in what’s being called a breakthrough, scientists have carried on an extended conversation with a humpback whale. They share the story of this remarkable encounter, their evidence that the creature understood them, and how the experiment informs our Search for Extraterrestrial Int...