This Week in Virology

In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell me...

The TWiV team reveals a variant SARS-CoV-2 that emerged in deer with deer-to-human transmission, and hybrid virus particles produced by co-infection with influenza virus and respiratory syncytial virus particles. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Kathy Spindler, and Brianne Barker Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of ...

In his weekly clinical update Dr. Griffin discusses human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks, changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States, updates on COVID-19–related mortality, impact of community masking on COVID-19, effectiveness of the COVID-19 vaccines against hos...

Cedric and John join TWiV to discuss their research showing that a human protein derived from an ancient retrovirus infection can protect against infection by other retroviruses. Hosts:  Vincent Racaniello , Rich Condit , and Kathy Spindler Guest: Cedric Feschotte and John Anthony Frank Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this e...

In his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar...

Michael Letko joins TWiV to discuss his research on understanding cell receptors required for sarbecovirus entry, including an ACE2-dependent isolate from Russian bats that is resistant to vaccine-induced antibodies. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit ,   Kathy Spindler , and Brianne Barker Guest: Michael Letko Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS...

In his weekly clinical update Dr. Griffin discusses high demand for Amoxicillin causing shortages amid child RSV surge, epidemiologic and clinical features of children and adolescents aged

Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts:  Vincent Racaniello , Alan Dove , Rich Condit ,  and Kathy Spindler Guest: Jake Scott Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  pat...

In his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, u...

From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Richard Knight about prion diseases and the outbreak of bovine spongiform encephalitis that led to cases of variant Creutzfeldt-Jakob disease in humans. Host:  Vincent Racaniello Guest: Richard Knight Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! L...

In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses...

David Quammen returns to TWiV to discuss how he wrote his new book 'Breathless', a story about the science and the scientists behind the race to understand the pandemic coronavirus SARS-CoV-2. Hosts:  Vincent Racaniello , Rich Condit ,   Kathy Spindler , and Brianne Barker Guest: David Quammen Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for...

In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative...

Angela Mingarelli joins TWiV to discuss whether the gut microbiota of bats confers tolerance to influenza virus infection in mice, and primate hemorrhagic fever-causing arteriviruses that can reproduce in human cells and might be capable of infecting humans. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit ,  and Brianne Barker Guest: Angela Mingarelli Subscribe (free):  A...

In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of...

Kathryn Hanley joins TWiV to discuss her career and the research in her laboratory on the molecular biology, evolution and ecology of emerging RNA viruses and their insect vectors. Hosts:  Vincent Racaniello , Rich Condit ,  and Kathy Spindler Guest: Kathryn Hanley Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Research assist...

In his weekly clinical update Dr. Griffin discusses high points of the multi-national monkeypox outbreaks, monkeypox virus genome mutations, possible occupational infection of healthcare workers with monkeypox virus, rates of monkeypox cases by vaccination status, protection of SARS-CoV-2 infection against reinfection, Paxlovid significantly reduces COVID-19 hospitalizations and deaths, and reboun...

Laurie Garrett discusses the role of wastewater testing in public health and her idea of a device that could be used by anyone to analyze water samples. This podcast is not an episode of TWiV, but I thought it would be of interest to listeners. Laurie Garrett and Vincent Racaniello Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episod...

Paul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit ,   Kathy Spindler , and  Brianne Barker Guest: Paul Offit Subscribe (free):  Apple Podcasts ,  Google Pod...

In his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vacci...

Eddie Holmes joins TWiV to discuss his role in the first release of the SARS-CoV-2 genome sequence, what really happened during the infamous Fauci teleconference, and evidence that the virus came from Nature and not from a lab. Hosts:  Vincent Racaniello and Dickson Despommier Guest: Eddie Holmes Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links...

Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , and Rich Condit Guest: Tom Monath Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV!...

In his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b...

From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Emma Thomson about the recent outbreak of pediatric hepatitis of unknown etiology and the finding that it is linked to infection by adenovirus-associated virus 2. Hosts:  Vincent Racaniello Guest: Emma Thomson Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Become a  patron  o...

In his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among v...