Authentic Biochemistry

Diabetes IX. The role of peroxisomes in ether-linked lipid biosynthesis. Dr.Daniel J. Guerra. 07March2022. Authentic Biochemistry Podcast production 08.03.2022 29:57 ↓

References Dr Guerra's lecture material

DiabetesVIII. Subcellular organization and the role of lipid metabolism in mitochondria and peroxisomes. Dr Daniel J. Guerra. 05March22. Authentic Biochemistry 05.03.2022 30:00 ↓

From Dr. Guerra's lecture archives

Diabetes VII. Cholangiocarcinomas and the corruption of the biliary system as sequalae of obesity and associated pancreatic exocrine insufficiency of diabetes. Dr Dan Guerra. 3.March.2022. A.B. 04.03.2022 29:48 ↓

References Dr Guerra's lecture notes World J Gastroenterol. 2013 Nov 14; 19(42): 7258–7266. Int J Endocrinol. 2015; 2015: 595649. PLoS One. 2017; 12(10): e0186643. BMC Cancer. 2019; 19: 185

Diabetes V . PEI and Diabetic Dyslipidaemia with Primary Cholagiocarcinoma. Primer on lipid digestion and Lipoprotein Trafficking. Dr. Dan Guerra. Authentic Biochemistry 01.March.2022 02.03.2022 30:00 ↓

References Dr. Guerra lecture notes BMC Cancer. 2019; 19: 185.

Diabetes IV. Pancreatic Exocrine Insufficiency in Types I, II, and III Diabetes Mellitus. Dr DAniel J. Guerra. 28.2.22. Authentic Biochemistry 01.03.2022 29:57 ↓

References Dr. Guerra Lecture notes Int J Endocrinol. 2015; 595649

Diabetes III. Sphingosine 1-Phosphate in glioblastoma and prostagladin E2/EP4 in diabetic nephropathy-an axis of angiogenesis. Dr. Daniel J. Guerra. 25.2.22 Authentic Biochemistry 26.02.2022 29:59 ↓

References Journal of Biological Chemistry.2013. 288 Issue 52 Pages 37355-37364. Prostaglandins & Other Lipid Mediators. 2022(April) . Volume 159, 106621

Diabetes II. The Insulin resistance factor and glucose intoxication associated dyslipidaemia and introduction to diabetic nephropathy. DJGPhD. 23.2.22. Authentic Biochemistry Podcast. 24.02.2022 29:53 ↓

References Dr. Guerra's lecture notes Prostaglandins & Other Lipid Mediators 2022.April. 159. 106621 Reviews in Endocrine and Metabolic Disorders. 2020. 21: 631–643 

Type 2 Diabetes I. Initial lecture describing insulin resistance and dyslipidaemia. Dr Daniel J. Guerra 22.2.22 Authentic Biochemistry Podcast. 23.02.2022 29:53 ↓

References Dr. Guerra lecture notes Reviews in Endocrine and Metabolic Disorders. 2020. 21: 631–643. J Lipid Res. 2015 Mar; 56(3): 588–598.

Fatty Acids IX. The Monounsaturated fatty acid inhibition of ferroptosis and apoptosis leads to cancer progression. Pharmacotherapeutic Considerations. Dr Daniel J. Guerra. 17.2.22 Authentic Biochem. 18.02.2022 30:00 ↓

References Dr. Guerra's notes-unpublished Cancer Res. 2019 Oct 15; 79(20): 5355–5366.

Fatty Acids VIII. The Potential for Ferroptosis enhancement via inhibition of Stearoyl CoA Desaturase as pharmacotherapy in Pancreatic Ductal Carcinoma.DJGPhD.16.2.22. Authentic Biochemistry. 16.02.2022 29:36 ↓

References Redox Biol. 2021 Jan; 38: 101807 Cancer Res. 2019 Oct 15; 79(20): 5355–5366.

Fatty Acids VII. Stearoyl CoA Desaturase biochemistry and assocation with immune and metabolic disease. Dr Dan Guerra 12.02.2022 29:27 ↓

References Dr Guerra Lecture notes Chem Biol Interact. 2019 Dec 12; 316: 108917 Chapter 7. Cook and McMaster. 2002. in Biochemistry of lipids, lipoproteins and membranes 4th edition. Elsevier Science. Vance and Vance eds.

Fatty Acids VI. The Inflammasome paradigm and transcription factor-mediated cytokine production as result of high carbohydrate diet and obesity. Dr. Daniel J. Guerra. 10.Feb 2022. Authentic Bichem. 11.02.2022 26:38 ↓

References Chem Biol Interact. 2019 Dec 12; 316: 108917 J Neuroinflammation. 2019; 16: 236.

Fatty Acids V. Ketogenesis as a therapeutic to redistribute preserved Heart Failure cardiac ejection fraction via blockage of mitochondrial protein hyperactylation. DJGPhD.9FEB22. Authentic Biochem. 10.02.2022 29:50 ↓

References Circulation Research 2020.Volume: 128, Issue: 2, Pages: 232-245, DOI: (10.1161/CIRCRESAHA.120.317933) J Neuroinflammation. 2019; 16: 236.

Fatty Acids IV. Adipocyte lipases and the Diacylglycerol PKC/PKD circuit of cellular degeneration leading to chronic inflammation-associated obesity. DJGPhD.07.Feb.22. Authentic Biochemistry 08.02.2022 29:59 ↓

References Adv Exp Med Biol . 2017;960:135-160. Lipids in Health and Disease volume 19 , Article number: 113 (2020) Circulation Research. 2020.Volume: 128, Issue: 2, Pages: 232-245

Fatty Acids III. The inflammatory diseases and the correlation to dyslipidaemia. Dr Dan Guerra. 05 February 2022. Authentic Biochemistry Studios. 06.02.2022 29:56 ↓

References Dr. Guerra's lecture notes Infect Immun . 2013 Dec; 81(12): 4478–4489 Am J Gastroenterol. 2004 Nov;99(11):2147-9 Front Immunol. 2019 Jun 7;10:1309 Nat Rev Gastroenterol Hepatol. 2019 Dec 9.

Fatty Acids II. Obesity and lipotoxicity. Dr Daniel J. Guerra. Authentic Biochemistry 04. February 2022 05.02.2022 29:57 ↓

References Dr. Guerra's lecture notes Int J Mol Sci. 2021 Jan; 22(1): 330

Fatty Acids I. Dr. Daniel J. Guerra. 03.02.22. Authentic Biochemistry Podcast 04.02.2022 29:57 ↓

References Dr. Guerra's lecture notes Int J Mol Sci. 2021 Jan; 22(1): 330.

Anabolism VII. The allosteric control of purine biosynthesis involves complementarity and recipricol maintenance of steady state ADP/GDP ratios. DJGPhD. 31.01.22. Authentic Biochemistry. 01.02.2022 29:59 ↓

References Dr. Guerra's lecture notes

Anabolism VI. de novo Purine Nucleotide Biosynthesis. Dr. Dan Guerra. 30.01.22. Authentic Biochemistry 30.01.2022 29:56 ↓

References Dr. Guerra's lecture notes  Mol Genet Metab Rep. 2021 Mar; 26: 100709.

Anabolism V. The nucleic acids. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast.28.01.22 29.01.2022 29:54 ↓

References Dr. Guerra's lecture notes

Anabolism IV. Cholesterologenesis. Dr Daniel J. Guerra. 26 January 2022. Authentic Biochemistry Podcast 27.01.2022 30:00 ↓

From Dr. Guerra's lecture notes

Anabolism III. Fatty acid synthesis de novo . Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Productions. 25.01.22 26.01.2022 29:41 ↓

References Dr. Guerra lecture notes

Anabolism II. The role of Acetyl CoA Carboxylase isoform expression and discrete allosteric regulation in controlling hepatic fatty acid metabolism. Dr Dan Guerra. 23.01.22. Authentic Biochemistry. 24.01.2022 29:59 ↓

Malonyl CoA controls the categorical/biochemical logic of hepatic glucose and lipid homeostasis via metabolic inhibition of metabolic antimony. References Dr Dan Guerra Biochemistry Lecture Notes. 2010-2021  Vance and Vance Biochemistry of Lipids, Lipoproteins and Membranes  4th ed. 2002. Elsevier Publisher.

Anabolism I. Dr Daniel J. Guerra Authentic Biochemistry Podcast Production 22.01.22 23.01.2022 30:00 ↓

Basic reductive biosynthesis as an exemplar for this first lecture in anabolism.

Membrane lipid provide the architectonic signatures for cellular interactions including avirulence and either systemic and systematic-inflammatory disease. DJGPhD. 17.1.22. AuthenticBiochemistry 17.01.2022 59:49 ↓

References J Biol Chem. 2016 Feb.  291(7): 3658–3667 J Biol Chem 2013 Dec. 288 (52): 37355-37364  Biophys J. 2005 Feb;88(2):1091-103 Infect Immun. 2018 Jul; 86(7): e00035-18