Beyond Longevity

Why do we lose muscle as we age, and how much can we rebuild, even in our seventies? For Dr Oskar Wenbar, the interest began after a stroke left his father bedridden. Watching his father’s physical condition deteriorate and his confidence disappear drew him into research on ageing muscle. In this episode, we look at what changes inside our muscles as we age, why it matters far beyond strength, and...

65 billion dollars. That is roughly what Nebius was worth on the stock market when we recorded this episode. Yet most people have never heard of it. So what does the company actually do, and why are scientists using its computing power to search for new treatments? Dr Ilya Burkov, Global Head of Scientific AI and Healthcare at Nebius, joins Beyond Longevity to explain how AI is being used in resea...

Longevity medicine has created a strange new kind of patient: the healthy person convinced something must be wrong. A wearable flags poor recovery. One test says your body is ageing faster than it should. Another gives you a completely different answer. And suddenly, someone who felt perfectly well starts wondering what needs fixing. In this episode, host Daphna Stern sits down with Dr Chris Bacht...

At 16, Chris Mirabile was lying in a hospital bed the night before brain surgery, wondering whether he would wake up the next morning. Years later, as he was building NOVOS, he lost his mother to pancreatic cancer. Those two experiences reshaped the way he thought about health and ageing, and eventually led him to found a longevity company built around a simple but demanding question: can we actua...

Recorded at HLTH Europe in Amsterdam, Part Two of our special series looks at four very different ways technology could help healthcare move earlier, become more personalised and make better use of the growing amount of health data we are collecting. Dr Marta Ciechonska, Co-Founder and CEO of Salient Bio, explores what the microbes living in our gut, mouth and vaginal microbiome can tell us about...

What happens when technology stops simply tracking our health and starts helping us understand what to do about it? Recorded at HLTH Europe in Amsterdam, this episode of Beyond Longevity features three conversations with founders working across very different areas of health technology. From understanding our individual stress response and making sense of an overwhelming amount of health data, to...

What if a vaccine could help the immune system clear senescent “zombie” cells — damaged cells linked to ageing, chronic inflammation and age-related disease? In this episode of Beyond Longevity, Daphna Stern sits down with David Scieszka, PhD, MBA, a biomedical scientist, computational biologist, and Founder and CEO of Vertical Longevity Pharmaceuticals (VeLo Pharma). His route into longevity has...

What if heart disease, kidney disease and dementia share a common mechanism linked to ageing? And what if blocking a destructive form of cell death called necrosis could help protect several organs at once? In this episode, host Daphna Stern speaks with LinkGevity founders Dr Carina Kern and Serena Kern-Libera about their attempt to develop a new longevity drug targeting necrosis, ageing and age-r...

At 39, Leslie Kenny was diagnosed with rheumatoid arthritis and lupus and says she was told she had around five years to live. More than two decades later, she is in long-term remission and has turned that experience into a mission: helping patients become better informed, more involved and more confident in decisions about their own health. In this episode, Leslie Kenny, founder of Oxford Healths...

Nearly two decades ago, Dr Gil Blander was trying to convince investors of an idea that, at the time, sounded radical: blood biomarkers should not only be used to diagnose disease, but to help healthy people understand what to change before disease develops. Some thought he was crazy. That idea became InsideTracker, the company he founded 17 years ago, which brings together blood biomarkers, genet...

In this episode of Beyond Longevity, Daphna speaks with Dr Peter Scriven, Co-Founder and Clinical & Scientific Director of LONGEVITY, about what longevity medicine should actually look like: moving from reactive, disease-led healthcare towards preventative, personalised medicine that tracks biomarkers, cardiovascular risk and health trajectory over time. Dr Peter describes much of conventional...

In this episode of Beyond Longevity, Daphna speaks with Jody Tropeano Greene, Head of Content at HLTH, and Alexa Mikhail, Senior Content Lead at HLTH US, about how HLTH identifies the healthcare topics that matter most, balances emerging trends with scientific evidence, and reflects the growing importance of longevity within modern healthcare. They explore the difference between healthy ageing—gro...

On Beyond Longevity, host Daphna speaks with Dr Sundeep Dugar, PhD, co-founder of BlueOakNx and the scientists behind the blockbuster cholesterol medicines Zetia (ezetimibe) and Vytorin. He explains how Zetia transformed cholesterol treatment by blocking cholesterol absorption in the intestine, and reflects on what it really takes to discover a breakthrough medicine: collaboration, perseverance, i...

Daphna sat down with Robert Gielow, founder of Mentry Pharma, to discuss what it really takes for foreign supplement and longevity companies to enter the pharmacy markets of Germany, Austria and Switzerland. He explains why many brands misunderstand the German-speaking market: distribution and pharmacy listings alone do not create demand, pharmacies are not straightforward sales channels, and scep...

Biology is undergoing one of the biggest transformations in its history. AI is helping researchers analyse enormous datasets, predict protein structures, identify drug targets, and accelerate scientific discovery in ways that would have been difficult to imagine just a few years ago. But AI is not replacing scientists. If anything, it is making human expertise, judgement, and scientific rigour mor...

Beyond Longevity interviews Kyle Holbert, COO and co-founder of Longevity Centres of America, about how unexplained fatigue, brain fog, depression, anxiety, joint pain and gut issues derailed his health despite a healthy lifestyle and years of searching for answers. After seeing multiple GPs and therapists who either dismissed his symptoms or could not identify a cause, Kyle discovered he had seve...

In this episode of Beyond Longevity, Daphna speaks with Nikolina Lauc, CEO and co-founder of GlycanAge, about glycobiology, immune ageing, and the role of chronic inflammation in ageing. Nikolina explains why glycans, the complex sugar structures attached to our antibodies, may offer one of the clearest windows into the state of the immune system. The conversation explores “inflammaging”, the idea...

Daphna sat down with Alan Graves, founder of DoNotAge, for an in-depth conversation about what it takes to make longevity science more credible, more collaborative and more accessible. After a serious health decline in his late twenties, Alan entered the longevity field after learning that ageing may be more malleable than he had once thought. He went on to build DoNotAge as a self-funded health r...

In this episode of Beyond Longevity, Daphna speaks with Dr David Cox, a health journalist (BBC, The Guardian, The Telegraph, NBC News and others), who holds a PhD in neuroscience from the University of Cambridge and is the author of The Age Code , about how diet, ultra-processed foods and the modern food environment shape biological ageing. Dr David argues that the longevity conversation often foc...

Supplements promise a lot: mitochondrial support, better brain health, healthier gut function, anti-ageing benefits and more. But how much of that is real science, and how much is simply clever wording on a label? In this episode of Beyond Longevity, Dr Luke Bucci, PhD, Chief Scientific Officer at Juvenon, brings both a scientist’s eye and decades of experience in the supplement industry to one of...

This week on Beyond Longevity, I am joined by Dr Herna de Wit, CEO and Founder of Omnisci Consulting, with a PhD in Biochemistry and an LLB in Law. Dr Herna brings a very unusual and valuable combination to the longevity conversation: deep scientific training, legal expertise and hands-on experience advising companies in the health, biotech and longevity space. Longevity is full of exciting scienc...

On Beyond Longevity, Dr Filippo Ongaro, medical doctor, entrepreneur, and strategic advisor, shares how nearly eight years working with astronauts at the European Space Agency shaped the way he thinks about ageing. In space, the body can lose muscle, bone and resilience at a frightening speed. Stress, sleep disruption, nutrition, movement and circadian misalignment are not lifestyle details. They...

Michael A. Clinton, former President of Hearst Magazines. Michael spent four decades at the top of the publishing world, including as President and Publishing Director of Hearst Magazines, before turning his attention to one of the biggest questions of our time. If many of us are likely to live longer than previous generations, how do we make the second half of life not just longer, but more inten...

What does good prevention actually look like, and is the longevity industry helping people live better, or simply making health feel more complicated? In this episode of Beyond Longevity, Daphna speaks with Niko Hems, Operations Lead at YEARS, a longevity clinic in Berlin, Germany. Niko brings a rare perspective to the conversation. He works inside the longevity field, but he is not afraid to chal...

In this ViVE conference bonus episode of Beyond Longevity, recorded live at the ViVE event in Los Angeles, the conversation explores how BioAro is seeking to bring different strands of personalised health data together within a single longevity platform. Brock Hay explains BioAro’s approach to integrating genomics, microbiome testing, biomarker analysis, AI-driven interpretation, and personalized...