Dr Daniel J. Guerra

Authentic Biochemistry

Science EN ↓ 1341 epizód

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Szerző

Dr Daniel J. Guerra

Kategória

Science

A podcast weboldala

podcasters.spotify.com

Legutóbbi epizód

2026. okt. 29.

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Epizódok

Invitation to Watch my Youtube lecture I on the Aging Human Dialectic. Link found in the show notes. DJGPhD 16.9.21 17.09.2021 2:04

https://youtu.be/4sW-BNVhzrs

Membrane Biochemistry Primer and Introduction to Aging. Dr. Daniel J. Guerra. Authentic Biochemistry Productions. 13.9.21 13.09.2021 29:54

Dr. Guerra introduces a primer on membrane biochemistry in preparation for a florid analysis of autophagy and the various forms of programmed cell death linked to the aging human. References Cell Discovery volume 7, Article number: 4 (2021)

Summer Fades and Aging Advances through non-coding RNA's and the Immunological Axes. Dr Daniel J. Guerra. 9.9.2021 Authentic Biochemistry Productions. 09.09.2021 29:50

Non coding RNA may regulate melanogenesis and in combination with plasma cell producing IgG the nutritional regulation of satiety. Aging results in alterations of this complex system thus resulting in localized melanogenesis and a corruption of the HPA axis. References: Aging (Albany NY). 2021 Jan 31; 13(2): 2700–2726. Stem Cells Int. 2020; 2020: 1047896. First Published online 2020 Jul 8 PNAS. 20...

Hepatic Gluconeogenesis and Glycogen Metabolism: Canonical Allostery. Dr Dan Guerra. Authentic Biochemistry 07 Sept. 2021 07.09.2021 29:57

Components of metabolic sequence toward gluconeogenesis in the human liver.

The hormonal and allosteric control over hepatic PFK2/FBPase2 via adenylate cyclase and Fructose 2,6 bis phosphate. DJGPhD.5Sept.2021. Authentic Biochemistry Productions. 05.09.2021 30:00

Dr. Guerra details the glucagon and epinephrine mediated control through Stimulatory G-protein couple adenylate cyclase activating PKA over Hepatic Glycolysis and Gluconeogenesis. 

Glycerol 3-phosphate dehydrogenase mechanism and the finale of glycolysis. Authentic Biochemistry. Dr. Daniel J. Guerra 27.8.21 27.08.2021 29:50

Utilization of a protein cysteine SH derived thioester intermediate alters the free energy hurdle for the synthesis of 1,3 bis PGA thus allowing for glycolytic ATP and NADH synthesis.

Haemoglobin: Molecular Oxygen Binding Cooperativity and the role of 2,3 bis phosphoglyceric acid. DJGPhD 19.8.21 20.08.2021 29:44

The interaction of glycolysis and lactic acid transport from skeletal muscle to the liver plays a significant role in oxygen uptake, transport and release in association with pulmonary carbon dioxide efflux . Dr. Daniel J. Guerra. An Authentic Biochemistry Production 19.8.21.

A Necessary Interruption in Amino Acid Catabolism: Haemoglobin and Oxygen Transport Lecture I. DJGPhD. 11 August 2021 11.08.2021 29:34

Any chronic decrease in the ability for molecular oxygen to bind to circulating Hb will diminish its availability in the Central Nervous System and Skeletal Muscle resulting in the potential for long-term Pathophysiology and Illness. Dr. Dan Guerra Published 11 August 2021. Authentic Biochemistry.

Amino Acid Catabolism (Continued): Neurotransmitter and S-adenosyl MET interconversions. DJGPhD 09 Aug 2021 09.08.2021 24:52

Classical Amino Acid Degradation Biochemistry : Emphasis on pathway interconversions and production of bioactive amines

Main Frame Amino Acid Degradation Pathways and Skeletal Muscle Performance and Ammonia Toxicity.02.Aug.2021. DJGPhD. Authentic Biochemistry 02.08.2021 30:00

J Physiol. 2005 563:285-90 Eur J Appl Physiol(2011) 111:2837–2843

The Urea Cycle and the endothelial ARGININE-Nitric Oxide Connection. DJGPhD 27.7.21.Authentic Biochemistry Podcast 27.07.2021 29:57

Biomedicines. 2020 Aug 6;8(8):277.

The Glutamate Dehydrogenase Axis Further Reveals the Role of Ischaemic Oxygen Availability for Neural Transmission in the Aging Brain. DJGPhD 20.7.21. 20.07.2021 29:30

Journal of Neurochemistry, Volume: 146, Issue: 4, Pages: 416-428, First published: 20 May 2018, DOI: (10.1111/jnc.14464

The Glutamate Axis of Bioenergetics, Neurotransmission and Potential Contribution to the Aging Senescent Phenotype. DJGPhD 20.7.21 20.07.2021 29:27

Journal of Neurochemistry, Volume: 146, Issue: 4, Pages: 416-428, First published: 20 May 2018, DOI: (10.1111/jnc.14464) Life Sci . 2019 Sep 1;232:116612

Amino acid metabolism I: An initial primer for subsequent discussions in Aging. Dr Guerra. 07July2021. Authentic Biochemistry. 12.07.2021 29:15

This is one of my classical biochemistry introductory lectures on amino acid utilization.

Mesenchymal stem cell fate and the mediation of age-associated senescence or plasticity in the elderly via immune response valency. DJGPhD 03 July 2021 04.07.2021 27:57

Trends in Immunology Volume 36, Issue 4, 2015, 217–228  Carcinogenesis 2015;36:1180-1192

Detailing the Senescent to Mesenchymal Transition in Aging : Links to Cancer vs. Apoptosis. DJGPhD 28 June 2021. 28.06.2021 29:34

Clinical and Molecular Allergy volume 15 , Article number: 21 (2017) Front. Immunol., 25 September 2019 | https://doi.org/10.3389/fimmu.2019.02247

Genomic damage, DDR, and the roles of inflammation and DNA epigenetic retailoring in the senescent phenotype. DJGPhD 24.6.21 25.06.2021 29:22

Oncotarget. 2013 Oct; 4(10): 1552–1553

Pharmacodynamics: General Considerations and Clinical Trials. Dr. Dan Guerra. Authentic Biochemistry 12 June 2021 12.06.2021 29:39

In this episode Dr. Guerra provides the overview of Pharmacodynamics .

Pharmacokinetics Synoptic with an Introduction to Aging Phenomena. Dr Daniel J. Guerra. 09June2021 authentic Biochemistry. 10.06.2021 29:36

A.D.M.E. Anesthesiology Clinics, 2019-09-01, Volume 37, Issue 3, Pages 475-492. Please subscribe and donate! Dr. Guerra needs your support!

Cardiovascular disease risk and malnutrition are associated with aging morbidity and obesity. Dr. Guerra. 8 June 2021. Authentic Biochemistry 08.06.2021 28:57

Risk factors for aging morbidity are linked to large variations in protein synthesis and lack of adipose derived TAG utilization. The immune  response becomes compromised during aging leading to states of hyperinflammation followed by hypo-immune sequalae opening up the potential for opportunistic respiratory infections and alterations in pulmonary endothelial membrane lipid fluidity restrict...

Ceramide mediated pathophysiology of aging-associated neurodegeneration. Dr. Dan Guerra. Authentic Biochemistry.05 June 2021. 05.06.2021 28:03

Seminars in Cell & Developmental Biology Volume 40, April 2015, Pages 115-126 Pharmaceutical Research March 2018, 35:49 Journal of Molecular Endocrinology 2017. 58, 1; 10.1530/JME-16-0182 J. Lipid Res. 2018 59:(3) 488-506.

Immuno Endocrine Regulation of Metabolism May-June 2021. Dr. Dan Guerra Authentic Biochemistry. 03.06.2021 29:42

Feng, T., Yang, X., Hao, S. et al. Immunol Res. 05 April 2020 Molecular Neurodegeneration volume 7, Article number: 45 (2012) J Biol Chem. 2019 Jun 7;294(23):9213-9224

Aging and Cancer Via Immunosenescence and Pro-inflammatory Cytokines: Relative loss of Naive T cell Populations in the Elderly. DJGPhD. 26 March 2021 26.05.2021 29:52

Annu. Rev. Physiol. 2013. 75:685–705 Nutrients. 2020 Mar; 12(3): 622

Pathobiochemical linkages between Alzheimer's Disease and Autism Spectrum Disorders: Associative Molecular Patterns with Diverse Pathologies. DJGPhD. 18 May 2021 19.05.2021 29:47

FASEB J. 2013 Jun; 27(6): 2458–2467. Scientific Reports volume 7, Article number: 13763 (2017)

Immunomodulatory effects on neuropsychiatric states: classic rodent model studies. Dr. Guerra. 17.5.21 Authentic Biochemistry 18.05.2021 29:00

Scientific Reports volume 9, Article number: 1220 (2019) Prog Neuropsychopharmacol Biol Psychiatry . 2005 Oct 12 Bulletin of Experimental Biology and Medicine .2003. 136.(3). 1573-8221  Pharmacological reports 2005, vol. 57, no6, pp. 811-817 Brain Res Bull, December 11, 2006; 71(1-3): 279-86. Journal of Endotoxin Research, Vol. 4, No. 5, 363-370 (1997) Scientific Reports volume 7, Article num...