Science (Video)

UCLA’s Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain’s periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari’s team discovered that these neurons are activ...

The land we now call Scripps Oceanography has been home to the Kumeyaay people for thousands of years. A history of encroachment, colonization and displacement from coastal lands has challenged Kumeyaay ocean traditions and practices. Today, Kumeyaay-Iipay-Tipay people are actively revitalizing Indigenous ocean culture. As part of Perspectives on Ocean Science Lecture Series, Stan Rodriguez and Pr...

It's time for a new narrative for the ocean, one that reflects current scientific knowledge and acknowledges innovative new partnerships and solutions that center the ocean in our future. In this program, Jane Lubchenco, Professor of Marine Biology at Oregon State University and with expertise in the ocean, climate change, and interactions between the environment and human well-being, talks about...

Three major global challenges – climate change, loss of biodiversity and its benefits, and inequality and inequity among people – are typically tackled within three separate silos. However, scientific knowledge tells us that the three are inextricably linked. If the problems are not considered together, solutions to one may undermine solutions to the others. Moreover, more holistic, integrated sol...

The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer r...

Humans have long been exposed to three main types of smoke: from early domestic fires, modern wildfires, and more recently, tobacco and fossil fuel pollution. All release tiny particles from partly burned plants, containing harmful chemicals like nitrogen oxides and carcinogens. These particles raise risks for lung cancer, dementia, and even childhood obesity. Studies show that air pollution can d...

The human gut microbiome is tightly linked our health. Our analyses of diverse human populations from around the globe, ranging from hunter-gatherer to industrialized, show that the gut microbiome is profoundly influenced by lifestyle. With a large collaborative team, we conducted deep metagenomic sequencing of the gut microbiomes of Tsimane horticulturalists from Bolivia and compared them to thos...

The essence of Being Human is the practice of Biocultural Reproduction (BCR). BCR is defined as the set of marriage and kinship based rules for extra-maternal cooperation in the production, feeding, and care of offspring. Human evolution theory needs to explain how people successfully combined a vastly extended period of offspring dependency and delayed reproduction with helpless newborns — with l...

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively...

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteo...

The Birch Aquarium celebrates the incredible contributions of women in the rich history of marine plankton research at Scripps. Judit Hersko performs part of her innovative series of visual narratives, "Pages from the Book of the Unknown Explorer," transporting you to Scripps’ early days through a cleverly imagined correspondence between Dr. Easter Cupp, Scripps' first female Ph. D. graduate, and...

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Trai...