BBC Inside Science

For the first time the gene editing technique CRISPR has been used by injecting the CRISPR instructions into the bloodstream rather than directly into the affected organ. In a trial, six adult patients showed improvements after the treatment was used to prevent the expression of deformed proteins associated with a genetic disease. The hope is this method could treat a range of other genetic diseas...

The Prime Minister has announced his desire for the UK to become a 'science superpower'. A new office within the cabinet to look at science will work alongside existing science strategy and funding structures. So far it's unclear where the responsibilities between the various science policy bodies lie. James Wilsdon, Professor of Research Policy at the University of Sheffield, helps Gaia Vince pic...

Scientists are now looking at the question of third doses of vaccines against SARS-Cov2, and this week the Cov-Boost trial was launched. It’s being run from University of Southampton and is going to be using seven different vaccines, some at half doses, in people over the age of 30 who were early recipients of their two doses. The Chief Investigator, immunologist Professor Saul Faust explains the...

Should we be vaccinating children in the UK against SARS-Cov 2? Children are rarely seriously ill if they catch Covid but infections mean missed school, and they can pass it onto older vulnerable people. The US, Canada, Israel and Dubai are some places that are already vaccinating the under 18s and Pfizer has recently published data from a trial of its mRNA vaccine in just over 2000 12-15 year old...

Sars Cov2, as the Covid19 coronavirus is called, probably began as the vast majority of new diseases do, when an animal virus infected a person – perhaps in a market or farm. There’s a large animal market in the city of Wuhan that sold wild as well as farmed animals, and studies have shown that different species of animals can infect each other with coronaviruses on their journey to market. But th...

Human impact on planet earth’s plant life might be detectable several thousand years back in fossil pollen cores taken from mud columns around the world. As Suzette Flantua and Ondrej Mottl describe in a paper published in the journal Science, a rapid acceleration in the changes in pollen species goes back further than we might have expected. This matters particularly when it comes to decisions ar...

Vic Gill talks to scientists who have cured a vaccine-induced blood clot patient, and meets a former top F1 chief engineer who wants to transform the fuel industry. Scientists in Vienna have been continuing to look at the rare blood clots associated with the AZ Covid-19 vaccination. Paul Knoebl describes to Vic his paper describing the diagnosis and successful treatment of a patient who developed...

Untreated wastewater "routinely released into UK rivers" is creating microplastic hotspots on riverbeds. That is the conclusion of a study in Greater Manchester, which revealed high concentrations of plastic immediately downstream of treatment works. The team behind the research concluded: untreated wastewater was the key source of river microplastic. Jamie Woodward takes Vic Gill wading in the Ri...

Despite being home to our early ancestors, attempts to find evidence of early burials in Africa have proved unsuccessful. That is until now. Professor María Martinón-Torres explains how findings from a 78,000-year-old Kenyan grave shed light on how our ancestors related to the dead. In keeping with the theme of clues from the past, Cardiff University academics have been studying the remains of cre...

Now that NASA engineers have successfully flown a helicopter remotely on Mars planetary scientists are exploring how to use the technology elsewhere. Marnie Chesterton talks to Elizabeth "Zibi" Turtle, from Johns Hopkins University who is working on a mission to fly a drone, called Dragonfly, above Titan, one of Saturn's moons. A new report that has measured the state of over 200 000 of the world'...

This week has seen a huge surge in Covid- 19 in India leading to concern of a "double mutant" variant, but what do we know about this B.1.617 as it is otherwise known. It was first described in October and is now in other countries including the UK. Virologist Dr Muge Cevik looks at the emerging evidence around vaccines and new variants. Climate change threatens coffee crops so it's exciting to kn...

The story of what we understand about the rare cases of blood clots associated with certain Covid-19 vaccines is constantly evolving. In today’s programme Professor Beverley Hunt looks at the emerging evidence. How have the restrictions due to Covid 19 affected how we grieve? Professor Claire White, an expert in grief and mourning, is investigating what it means to the grief process when the tradi...

In 2016, an accelerator physics centre called Fermilab acquired a massive circular 50 foot magnet from a lab in New York. Too big for the roads, the magnet had to take a 2000km detour via New Orleans to get to its new home. This was the start of the “muon g-2” experiment. Last week, Fermilab announced some of their results, and they don’t quite add up. UK experiment lead Professor Mark Lancaster f...

Scientists were delighted earlier this year to find they would still have access to the EU Horizon 2020 funding and collaborations. Now, it has been revealed that membership of this group, which was previously paid for through fees to the European Union, may come directly from the science budget, at a cost of about £15 billion over the next 7 years. That’s £1-2 billion a year. Marnie Chesterton sp...

The UK is reportedly halfway towards meeting its 2050 target of "net zero" carbon emissions. How did we get there and how will we achieve the next stage? ‘UK greenhouse gas emissions in 2020 were 51% below 1990 levels, according to a new Carbon Brief analysis. This means the UK is now halfway to meeting its target of “net-zero” emissions by 2050.’ Simon Evans explains his predictions from the repo...

We still know very little about exactly how the embryo forms out of a mass of dividing cells in those crucial first weeks after conception. This is also the time when many miscarriages occur, and scientists want to understand why. Couples going through IVF donate spare embryos for research and scientists are permitted to study them in a test tube, or in vitro, allowing them to grow and develop for...

On Friday 5th March China published a draft for its 14th five-year plan in Beijing. The document acts as a national economic blueprint and was expected to provide an outline as to how the world’s biggest emitter of greenhouse gas emissions planned on tackling its target of reaching net zero emissions by 2060, put forward by President Xi Jinping last September. It appears that greenhouse emissions...

With global warming continuing to increase at an alarming rate, we need all the help we can get to lock up the carbon that we’ve released into the atmosphere. Fortunately, plants have evolved to do just this, but there’s a whole class of plants that often get forgotten: the mangroves and seagrasses that grow between land and sea, which are among the planet’s most effective carbon sinks. Gaia Vince...

On Thursday, The UN Environmental Programme published a report called Making Peace With Nature. It attempts to synthesise vast amounts of scientific knowledge and communicate “how climate change, biodiversity loss and pollution can be tackled jointly within the framework of the Sustainable Development Goals”. But it also offers clear and digestible messages that governments, institutions, business...

On Thursday 18th Feb 2020 Nasa’s Perseverance Rover is due to touch down – gently and accurately – in the Jezero crater on Mars. Using similar nail-biting Sky Crane technology as its predecessor Curiosity, if successful it will amongst many other things attempt to fly the first helicopter in the thin Martian atmosphere, and leave small parcels of interesting samples for future missions to collect...

Victoria Gill and guests discuss the signs and symptoms of melting ice and anthropogenic climate warming, illicit CFC production and the racket we make in the seas. As two robotic missions from UAE and China arrive at Mars , and a third from NASA arrives next week, UK astronaut Tim Peake talks of the international collaboration in Mars research that is to come. And continuing BBC Inside Science's...

Ahead of the COP summit in Glasgow at the end of the year, this week an important study was published that attempts to enumerate the value of biodiversity in the economics of humankind. Prof Sir Partha Dasgupta's review makes it clear how essential and yet vulnerable it is. Trees play a large part in the biosystems of the planet, and replanting them is often touted as a solution to many of the car...

A year after the first SARS-Cov2 sequences were received in the vaccine labs, Dr Alex Lathbridge and guests look into ongoing development and what next year's booster shots might be like. Prof Robin Shattock's team at Imperial College are still working on their vaccine technology - called 'Self Amplifying RNA' or saRNA. A little bit behind their well financed corporate colleagues, this week they a...

Reports this week talk of some BAME ethnic minorities being significantly less likely to take a covid vaccine if offered. Vittal Katikireddi and Tolullah Oni both sit on the SAGE ethnicity subgroup, and they discuss with Alex Lathbridge where the figures come from and quite what they might mean. Some of these same groups have suffered some of the worst outcomes from infection. Addressing any under...

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief. Of all the ways the UK can now diverge from...