The Stem Cell Podcast

Guest: Dr. Miki Ebisuya is a Group Leader at the European Molecular Biology Laboratory in Barcelona. Her lab focuses on synthetic developmental biology, where they reconstitute developmental mechanisms by making artificial gene circuits, and study interspecies differences by comparing organoids of different animals. Featured Products and Resources: ESC & iPSC News mTeSR™ Plus The Stem Cell Sci...

Guest: Dr. Tom Cheung is an S H Ho Associate Professor of Life Science at the Hong Kong University of Science and Technology. His lab investigates the molecular pathways that control muscle stem cell quiescence and stem cell-mediated tissue regeneration. Featured Products and Resources: Muscle Cell News STEMCELL Technologies Human MyoCult™ Workflow The Stem Cell Science Round Up Organoid Model of...

Guest: Dr. Ludovic Vallier is a Professor of Regenerative Medicine at the Cambridge Stem Cell Institute and Director of the NIHR Cambridge Biomedical Centre hiPSC core facility. His lab studies the basic mechanisms controlling the differentiation of pluripotent cells into endoderm progenitors from which the pancreas, lung, gut and liver originate. Featured Products and Resources: Technical Resourc...

Guest: Dr. Valerie Horsley is an Associate Professor of Molecular, Cellular, and Developmental Biology, and Associate Professor of Dermatology at Yale University. Her lab studies how adult stem cells within epithelial tissues maintain tissue homeostasis, wound healing and can contribute to cancer formation. Featured Products and Resources: Webinar: Building Brain Organoids and Assembloids to Study...

Guest: Dr. Henner Farin is a Young Investigator in the German Cancer Consortium, and a Junior Research Group Leader at the Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy. His group uses organoids to study cell signaling in intestinal stem cells and colorectal cancer. Featured Products and Resources: CRISPR-Cas9 Genome Editing of Human Intestinal Organoids Try STEMCELL Techn...

Guest: Dr. Sergiu Pașca is an Associate Professor of Psychiatry and Behavioral Sciences at Stanford University, and the Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program. His team has developed methods for generating human brain organoids, and uses them to study the programs underlying brain development, assembly and dysfunction. To learn more about his research, regi...

Intro: In June 2020, we attended the International Society for Stem Cell Research (ISSCR) virtual annual meeting! Here is the second of three special episodes from the meeting featuring Dr. Martin Pera, Principal Investigator at the Jackson Laboratories, who presented on the unique properties of a subset of human pluripotent stem cells with a high capacity for self-renewal. Guest: Dr. Martin Pera...

Guest: Dr. Dominique Bonnet is the Group Leader of the Hematopoietic Stem Cell Laboratory at the Francis Crick Institute in London, UK. Her lab is interested in the extrinsic mechanisms that regulate hematopoietic stem cells, and how they can intervene in order to eradicate the leukemic stem cell. Featured Products and Resources: Science News by STEMCELL Technologies MesenCult™-ACF-Plus medium The...

Intro: In June 2020, we attended the International Society for Stem Cell Research (ISSCR) virtual annual meeting! Here is the second of three special episodes from the meeting featuring Dr. Kristy Red-Horse, Associate Professor of Biology at Stanford University, who presented on using developmental biology to inform cardiac tissue regeneration. Guest: Dr. Kristy Red-Horse is an Associate Professor...

Guest: Dr. Valentina Greco is the Carolyn Slayman Professor of Genetics at Yale University. Her lab has developed novel live imaging approaches to track and manipulate stem cells in live animals, allowing them to study the complex orchestration of tissue regeneration using the skin as a model system. She is also a fierce advocate for inclusivity in the scientific community. Featured Products and R...

Intro: In June 2020, we attended the International Society for Stem Cell Research (ISSCR) virtual annual meeting! Here is the first of three special episodes from the meeting featuring Dr. Madeline Lancaster, Group Leader at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK, who presented on new directions for human brain organoids. Guest: Dr. Madeline Lancaster is a Gr...

Guest: Dr. Benoit Bruneau is the Director of the Gladstone Institute of Cardiovascular Disease. His lab uses mouse models and human iPSCs to investigate the transcription factor networks that regulate sets of genes critical for heart development. Featured Products and Resources: Muscle Cell News STEMdiff™ Cardiomyocyte Media and Supplements The Stem Cell Science Round Up New Bone Grafts from Stem...

Guest: Dr. Karl Koehler is an Assistant Professor of Otolaryngology at Harvard Medical School. His lab develops organoid systems to study human sensory organ development and function, and to model congenital diseases and develop regenerative medicine therapies for the inner ear and various craniofacial tissues. Featured Products and Resources: Dermal Cell News Wiley eBook: Organoid Research Techni...

Guest: Dr. Freda Miller is a Senior Scientist at the Hospital for Sick Children and Professor at the University of Toronto. Her research focuses on the cellular mechanisms that regulate development of the mammalian nervous system, with a particular interest in stem cells and trophic factors. Featured Products and Resources: Neural Disease Modeling Hub STEMdiff™ Neural Crest Differentiation Kit The...

Guest: Dr. Hans Clevers is a Group Leader at the Hubrecht Institute for Developmental Biology and Stem Cell Research. Dr. Clevers pioneered research into the Wnt signaling cascade, Lgr5 as a marker of tissue stem cells, and organoid technology. His group studies the molecular mechanisms of tissue development and cancer of various organs using organoids made from adult Lgr5 stem cells. Featured Pro...

Guest: Dr. Sheila Chari is the Editor-in-Chief at the journal Cell Stem Cell, and Executive Editor at Cell Press . After completing her postdoc, she moved away from the bench and became the Reviews Editor at Cell Stem Cell. As the Editor-in-Chief, Dr. Chari’s primary responsibilities are knowing and publishing the top stem cell discoveries, driving journal publishing strategy, and managing a globa...

Guest: Dr. Josef Penninger is the Director of both the Life Sciences Institute at the University of British Columbia, and the Institute for Molecular Biotechnology of the Austrian Academy of Sciences in Vienna, Austria. He was previously on the podcast to talk about his research developing human blood vessel organoids. Recently, Dr. Penninger’s team has identified a trial drug that can signi...

Guest: Dr. Darcy Wagner is an Associate Professor in the Lung Bioengineering and Regeneration group at the Lund Stem Cell Center. Her team uses a multidisciplinary approach to understand how the extracellular environment directs stem cell behavior for endogenous and exogenous lung tissue regeneration. Featured Products and Resources: #StemCellfie Contest Digital and Remote Resources for Your Lab

Guest: Among his many appointments, Dr. Deepak Srivastava is the President of the Gladstone Institutes and the International Society for Stem Cell Research, and co-founder of Tenaya Therapeutics . His lab investigates the gene networks that guide cardiogenesis by developing models of heart disease using patient-derived iPSCs and CRISPR technology. Featured Products and Resources: Webinar: Modeling...

Guest: Dr. Jeanne Loring is a Professor Emeritus and Director of the Center for Regenerative Medicine at the Scripps Research Institute, and the Co-Founder of Aspen Neuroscience. Her lab works on a diverse range of projects using iPSCs, including developing cell replacement therapies for Parkinson’s disease, sending neural organoids into space, and partnering with the San Diego Zoo to make iPSCs f...

Guest: Dr. Joy Wu is an Associate Professor of Medicine at Stanford University, and a a board-certified endocrinologist.  With both basic and translational research, her lab investigates stem cell therapies for bone formation and the prevention of cancer metastases to bone, as well as the bone marrow hematopoietic niche. Featured Products and Resources: Embryonic Stem Cell News mTeSR™ Plus The Ste...

Guest: Dr. Thomas Reh is a Professor of Biological Structure at the University of Washington School of Medicine. H is lab is studying retinal development and disease using organoids, and developing methods of transplanting stem cells for retinal repair in non-human primates. Their goal is to stimulate more effective regeneration in the retina to restore vision in people that have lost their sight....

Guest: Priye Iworima is a PhD student at the University of British Columbia. Her project is focused on developing and optimizing a differentiation protocol for generating insulin-producing cells derived from stem cells that could be used as a potential therapy for type 1 diabetes. She is also working on optimizing process parameters to facilitate the large scale manufacturing of the cells. Feature...

Guest: Dr. Kacey Ronaldson-Bouchard is an Associate Research Scientist in the Laboratory for Stem Cell and Tissue Engineering at Columbia University, focusing on biomedical engineering. She is also the co-founder of TARA Biosystems, which offers physiologically relevant human “heart-on-a-chip” tissue models for cardiac risk assessment and drug discovery applications. She also a strong supporter of...

Guest: Dr. Todd McDevitt is a Senior Investigator at the Gladstone Institutes. He is also Program Director of the University of California, San Francisco’s Bioengineering Graduate Program (joint with UC Berkeley), and a Professor at UCSF’s Department of Bioengineering and Therapeutic Sciences. His research focuses on engineering 3D, multicellular systems that can be used to study princ...