Future Science Group

In this NCTalks podcast, Lauren Pulling, Editor of Neuro Central, is joined by Claude Wischik. Prof Wischik is board-certified in psychiatry and a professor of Old Age Psychiatry at the University of Aberdeen (UK). A pioneer in tau research, he discovered the tau protein compositional structure of Alzheimer’s tangles and established that it was possible to dissolve these tangles with pharmaceutica...

How can we bring Parkinson’s disease into the age of personalized medicine? One such approach recently described by Alberto Espay (University of Cincinnati, OH, USA) is to subtype the disease according to the presence of certain biomarkers. This is an approach that he says could “up the ante in our ability to modify the disease”, moving us away from purely dopaminergic strategies that address only...

Whilst at the AAN Annual Meeting (Boston, MA, USA, 22–28 April) last month, we caught up with Regina Katzenschlager, Medical University Vienna and Danube Hospital (both Vienna, Austria), whose research into the use of apomorphine for Parkinson’s disease was highlighted at the conference as one to watch. In this interview, Regina tells us more about the recent Phase III trial, which provided eviden...

Helen McShane discusses her work leading the TB vaccine research program at Oxford University, and shares her thoughts on the challenges facing vaccine development and eradication of this disease.

Listen to this interview with Peter Stern (University of Manchester, UK) to discover more about chemotherapy resistance in acute lymphoblastic leukemia and novel strategies to overcome it.

While at the AAN Annual Meeting (Boston, MA, USA, 22–28 April 2017), we spoke with Dr Michael Alosco, a fellow at Boston University Alzheimer’s Disease and CTE Center(MA, USA), who is currently working on multiple projects looking at chronic traumatic encephalopthy (CTE)in both living and deceased patients. Michael discussed his work, progress towards diagnosis of CTE in life and his thoughts on t...

Reporting from ECCMID17, we spoke to William Irving about his current work on hepatitis C and his thoughts on the future of this field.

Whilst at the American Academy of Neurology’s Annual Meeting (Boston, MA, USA, 22–28 April 2017), we sat down with Michael Pender (University of Queensland, Australia), who was presenting promising interim findings from a Phase 1 study investigating a novel treatment for multiple sclerosis (MS) at the meeting. In this interview, Dr Pender discusses the relationship between MS and the Epstain-Barr...

In this interview, Joop Arends discusses his thoughts on the future of diagnosis and management of hepatitis C, and also gives us his highlights from ECCMID.

In this interview, Greg Roman (Waters Corporation, USA) shares his experience with instrumentation and techniques such as LC–MS and HRMS and explains what drew him to the field.

In this edition of NCTalks, Lauren Pulling speaks to Emery Brown, Professor of Anesthesia at Harvard Medical School (MA, USA). Dr Brown has delivered a number of lectures in recent years on deciphering the dynamics of the brain under general anaesthesia, and how the potential of this area may currently be under-utilized. In this podcast we’ll hear more about Dr Brown’s work, how general anesthesia...

In this EpigenomicsNet podcast, Professor Hendrik Stunnenberg (Radboud University, Nijmegen, Netherlands) discusses his work in gene expression, investigating regulatory epigenetic mechanisms and provides a summary of his talk on the epigenome of innate immune cells.

In this EpigenomicsNet podcast, Dr En Li (Novartis Institutes for BioMedical Research, Shanghai, China) discusses his work leading Novartis’ research program in Shanghai and provides a summary of his talk on Novartis’ epigenetic research in cancer.

In this EpigenomicsNet podcast, Dr Danette Daniels (Promega, Madison, WI, USA) discusses her work at Promega in the area of functional proteomics and provides a summary of her talk introducing Promega’s technologies to study and characterize protein interactions inside cells, particularly for chromatin analysis.

In this MedChemNet podcast, Professor Paul Fish (University College London, UK) discusses his work in Alzheimer’s drug discovery and the talk he delivered on the discovery of fit for purpose chemical probes to investigate bromodomain proteins and the three new drug discovery institutes funded by Alzheimer’s research UK.

In this MedChemNet podcast, Professor Michelle Arkin (University of California, San Francisco; San Francisco, CA, USA) discusses her work in academic drug discovery and chemical biology and the talk she delivered on the progression of inhibiting protein-protein interactions and utilizing this to potentially re-modulate disease networks to a healthy state.

In this MedChemNet podcast, Dr Gemma Nixon (University of Liverpool, UK) discusses her work in antimalarial, antituberculosis, anti-filariasis and antifungal drug discovery and development and the talk she delivered on the development of the antimalarial E209.

In this podcast Dr Elizabeth Whittaker, Dr James Seddon, Dr Pete Dodd and Professor Beate Kampmann discuss their work in pediatric tuberculosis focusing on the areas of immunology, modelling and drug resistance.

In this edition of NCTalks, we speak to Robyn Klein, a Professor of Medicine, Immunobiology and Neuroscience at Washington University School of Medicine in St Louis, Missouri in the USA. Robyn’s research focuses on the pathogenesis of neuroinflammatory diseases in the CNS, specifically the mechanism of leukocyte recruitment into the CNS, and the direct effects of inflammatory mediators on resident...

Two key themes to come out of the Alzheimer’s Research UK (ARUK) Conference (Aberdeen, UK, 14–15 March 2017) were the celebration of world-class research, and hope for the future of dementia understanding, prevention and treatment, particularly with the forging and strengthening of new partnerships, collaborations and initiatives. In May 2016, ARUK committed £50 million to support the MRC-led UK D...

In part 2 of The Changing World of Bioanalysis our panelists discuss what the bioanalytical lab of the future might look like. Discussions included: The need for bioanalysts to acquire more biological skills in order to understand newer generation of complex molecules. Convergence of different units of companies and merging of skills. The role of automation in the bioanalytical lab of the future.

In part 1 of this 3-part video filmed at Barcelona our panel of experts discuss the issue of skills gap in the bioanalytical laboratory and the changing nature of the relationship between Pharma and CROs as outsourcing continues to increase. Discussions include: - Decreasing current skills gap evident in most bioanalytical labs, particularly in younger generation of bioanalysts. - Collaborations b...

In this RegMedNet podcast, Mike Rice explains the make or break impact of biopreservation in the potential commercialization of cell therapies.

Our RegMedNet Podcast talks to Dr Aric Rogers about how he is studying factors such as genetic variations and environmental conditions that can influence life span using roundworms. Dr Rogers provides his thoughts and predictions on how dietary restriction for therapeutic benefits could be adopted for the future.

Our RegmedNet Podcast talks to Dr Sandra Rieger about how the Rieger lab uses zebrafish as a model to study wound healing mechanisms and nerve regeneration in peripheral neuropathy. Dr Sandra Rieger provides her thoughts and opinions on the future of zebrafish in research, and future regenerative medicine therapies.