Sam and Karine
Two Onc Docs
This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*
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Metastatic Colon Cancer 2025 UPDATE 11.03.2025 23:45
Today’s episode is focusing on what you need to know regarding metastatic colon cancer. This will include the need to know about molecular studies, treatment, and surgery for oligometastatic disease. There has been three breakthroughs since we last covered this topic in the treatment of metastatic CRC based on molecular findings that we will go over today.
Localized Colon Cancer 2025 UPDATE 03.03.2025 40:25
Today’s episode is focusing on what you need to know regarding early stage colorectal cancer (CRC) as of 2025. The last time we covered this topic was in 2023 and things continue to change. We will go over all the important details on the diagnosis, presentation, diagnostic work-up, role of ctDNA, staging, treatment, and surveillance of localized CRC.
Multiple Myeloma 2025 x Dr. Vincent Rajkumar Part 2 24.02.2025 19:13
We are so honored to welcome back Dr. S. Vincent Rajkumar, Professor of Medicine at the Mayo Clinic in Rochester, Minnesota. He is also Editor-In-Chief of Blood Cancer Journal and the Chairperson of the Board of the International Myeloma Foundation. This week’s episode will be focusing on additional pearls for the treatment of Multiple Myeloma including options for refractory disease, as well as a...
ASCO GU 2025 Takeaways 18.02.2025 13:22
Today we will be discussing a few of the exciting abstracts presented at ASCO GU (Feb 13-15 2025) for prostate CA (TALAPRO-2), bladder CA (EV-302, CM-274, NIAGARA), and RCC (COSMIC-313, KIM-1).
ASCO GU 2025 Preview 10.02.2025 10:46
Today we will be discussing exciting data to come at ASCO GU (Feb 13-15 2025) in terms of research for prostate CA, bladder CA, RCC and other rarer GU tumors.
Multiple Myeloma 2025 x Dr. Vincent Rajkumar Part 1 03.02.2025 17:34
We are so honored to welcome Dr. S. Vincent Rajkumar, Professor of Medicine at the Mayo Clinic in Rochester, Minnesota. He is also Editor-In-Chief of Blood Cancer Journal and the Chairperson of the Board of the International Myeloma Foundation. This week’s episode will be focusing on Multiple Myeloma symptoms, diagnostic criteria, work-up and initial treatment.
Small Cell Lung Cancer 2025 x Dr. Stephen Liu Part 2 27.01.2025 34:24
This week’s episode will be focusing on additional details for Extensive Stage Small Cell Lung Cancer (SCLC), options for relapsed/refractory disease & advice for trainees. We are so excited to welcome back Dr. Stephen Liu international expert for lung cancer, Director of Thoracic Oncology & Developmental Therapeutics at Georgetown Lombardi Cancer Center and Co-Host of the IASLC Podcast.
Small Cell Lung Cancer 2025 x Dr. Stephen Liu Part 1 20.01.2025 23:32
This week’s episode will be focusing on Small Cell Lung Cancer (SCLC). We will go all the important details on risk factors, diagnostic work-up, staging and treatment of both locoregional and metastatic SCLC. We are so excited to welcome Dr. Stephen Liu international expert for lung cancer, Director of Thoracic Oncology & Developmental Therapeutics at Georgetown Lombardi Cancer Center and Co-H...
Polycythemia Vera 2025 15.01.2025 12:26
This week’s episode will be re-discussing one of the myeloproliferative neoplasms, Polycythemia Vera (PV). We will go over the important details on the diagnosis, risk stratification for thrombus and treatment.
Immune Related Adverse Events (irAEs) 06.01.2025 17:30
Happy New Year! This week’s episode will go over important details related to immune checkpoint inhibitors (ICIs) and immune-related adverse events (irAEs), with general management strategies for each of the most common iRAEs.
Thymoma x Dr. Pat Loehrer Part 2 16.12.2024 19:34
This week’s episode will be focusing on advanced Thymoma and Thymic Carcinoma, board review pearls, and career advice for trainees & early career oncologists. We are back with Dr. Pat Loehrer, who is a legend when it comes to the treatment of Thymoma.
Thymoma x Dr. Pat Loehrer Part 1 09.12.2024 22:55
This week’s episode will be focusing on localized Thymoma and Thymic Carcinoma. We are so honored to have Dr. Pat Loehrer here with us today who is a legend when it comes to the treatment of Thymoma. He is a Distinguished Professor of Medicine Joseph W. and Jackie J. Cusick Professor of Oncology, Director for Center of Global Oncology and Health Equity and prior cancer center director at Indiana U...
Metastatic Non-Small Cell Lung Cancer 2024 UPDATE 25.11.2024 20:48
This week’s episode will be focusing on Metastatic Non-small Cell Lung Cancer (NSCLC). We are back with Dr. Jennifer Marks, Thoracic Oncologist at the Dana-Farber Cancer Institute. We will go all the important details on the quickly growing and changing systemic therapy options including traditional chemotherapy, immunotherapy and targeted agents
Localized Non-Small Cell Lung Cancer 2024 UPDATE 18.11.2024 25:15
This week’s episode will be focusing on Localized Non-small Cell Lung Cancer (NSCLC). We are very excited to have Dr. Jennifer Marks with us today. Dr. Marks is a thoracic oncologist at the Dana-Farber Cancer Institute, Instructor in Medicine at Harvard Medical School, who also recently took her oncology boards. We will go all the important details on basic of staging, treatment for resectable and...
Hemoglobin Electrophoresis 11.11.2024 19:39
This week’s episode will be focusing on Hemoglobin (Hb) electrophoresis. We will go important details on what Hb electrophoresis is, the normal breakdown of adult hemoglobin, and specific hemoglobinopathies (thalassemias, sickle cell, Lepore...) you can be tested on during your ITEs and hematology boards.
Special Guest: CRC Survivor & Patient Advocate Marisa Peters 28.10.2024 26:27
In honor of National Family Health History Month in November, we have a special guest. We share the story of an incredible colorectal cancer survivor and health advocate, Marisa Peters, who was a Broadway vocalist and a very healthy, active mom to 3 young boys, yet diagnosed with stage 3 rectal cancer at only 39 years old.
Metastatic Breast Cancer 2024 UPDATE 21.10.2024 20:14
This week’s episode is part 3 of 2024 updates focusing on treatment options for metastatic breast cancer. We will cover important details on systemic therapy related to metastatic breast cancer & key toxicities. We are honored to have Dr. Eleonora Teplinsky, a board-certified medical oncologist specializing in breast and gynecologic oncology, as a guest sharing some pearls.
Localized Breast Cancer 2024 UPDATE 14.10.2024 28:49
This week’s episode is part 2 of 2024 updates focusing on treatment options for localized breast cancer. We will discuss important details on radiation, as well as therapies based on ER/PR/her2 receptor status. We are honored to have Dr. Eleonora Teplinsky, a board-certified medical oncologist specializing in breast and gynecologic oncology, as a guest sharing some pearls.
Breast Cancer Screening, Prevention & Intro 2024 UPDATE 07.10.2024 16:36
We are continuing our 2024 updates, this week’s episode will be an intro to breast cancer. Today’s will include high yield tips on screening, prevention, ductal carcinoma in situ DCIS, lobular carcinoma in situ LCIS, as well as introduce invasive localized disease.
Board Review Resources 2024 30.09.2024 15:25
This week’s episode will be discussing our favorite heme/onc board review resources. This is pertinent to new fellows who are starting to think about how to study during fellowship, preparation for ITEs and of course studying for the boards.
ESMO 2024 GU Update 23.09.2024 18:10
We are doing a special episode this week to cover some of the key GU abstracts from ESMO 2024. We cover an update on the STAMPEDE prostate cancer trial, SUNNIFORECAST in non-clear cell renal cell carcinoma, SunRISe-4 in bladder cancer, and more.
Palliative Care x Dr. Janet Abrahm Part 2 16.09.2024 19:55
In Part 2 we discuss how to deal with patients of different backgrounds, navigating spiritual & emotional challenges in oncology, tips for physicians who are experiencing moral distress & compassion fatigue, as well as general career advice. We are so honored to have Dr. Janet Abrahm with us who is a national leader in the field of palliative care and a professor at Harvard Medical School...
Heme & Onc Fellow Board Review Tips 2024 09.09.2024 16:03
This week’s episode will be focusing on final board review tips. We will go over our highest yield cheat sheet topics, and how we prepared the days leading up to our exam. We took our boards three years ago now, but the stress leading up to the exam is certainly fresh in our minds.
Palliative Care x Dr. Janet Abrahm Part 1 27.08.2024 27:44
In Part 1 we discuss how to explain palliative care to patients, pain and anti-emetic management, non-pharmacologic strategies, and current innovations within palliative care. We are so honored to have Dr. Janet Abrahm here with us who is a national leader in the field of palliative care and a professor at Harvard Medical School.
Hemophilia 2024 UPDATE 19.08.2024 16:22
This week’s episode will be repeating our episode on hemophilias with some updates. We will go over all high yield facts regarding both hemophilia A and B for your boards and end with a little bit about acquired hemophilias.
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