tv.qiagenbioinformatics.com

Viral constructs are essential tools for gene therapy, vaccine development and advanced cell engineering workflows. QIAGEN CLC Genomics Workbench has the tools to streamline each stage of construct development, from in silico design to resequencing analysis and adventitious agent detection. In this webinar, you will learn how to build custom viral variants, verify construct integrity using NGS dat...

Biomedical knowledge graphs are powerful tools for organizing complex biological information and uncovering relationships that are difficult to see in traditional data formats. This introductory webinar is for researchers new to knowledge graphs who want to understand how they can support hypothesis generation, target discovery and data exploration. You will explore: - The fundamental concepts beh...

In this era of precision medicine, do you have what it takes to leverage next-generation sequencing (NGS) data towards better cancer research, diagnostics and patient care? Join our interactive workshop and learn how Human Gene Mutation Database (HGMD) Professional can help you uncover germline variant insights using expert-curated data. Explore almost 50 years of curated variant knowledge, spanni...

This is the last part of a series that will show how you can easily turn your ‘omics data into actionable insights using QIAGEN Ingenuity Pathway Analysis (IPA). Here, we take you deeper into the expert-curated content in the QIAGEN Knowledge Base. You will learn: How findings from publications are curated into the knowledge base Which tools you can use – with or without a dataset – to investigate...

In an era of near-limitless public experimental data but little standardization, meaningful insights are lost to noise. Large collections of quality experimental data are essential for big-picture discoveries that stand up to scrutiny. In this webinar, you will learn how to feed your drug discovery programs by integrating connections mined from QIAGEN Biomedical Knowledge Base with deeply-curated...

Accurate interpretation of cancer genomics depends on standardized disease classification, tumor characterization and variant annotation. In this joint COSMIC and QIAGEN webinar, we show how these robust frameworks enable reliable cohort building and reproducible research.   The webinar covers three themes:  Disease classification: COSMIC’s tumor classification and mapping to NCI Thesaur...

Advances in genomic medicine hold enormous promise, but that promise cannot be fully realized without greater diversity in research and clinical application. In this webinar, Eimear Kenny will discuss how population genetics can drive more accurate, equitable genomic health by expanding representation in genomic studies and databases. Drawing on work from her group at the Icahn School of Medicine...

In this training, you will learn how to analyze and interpret your own single cell RNA-seq data using QIAGEN CLC Genomics Workbench starting with either FASTQ or matrix files. Using CLC Genomics Workbench, you will learn how to perform secondary analysis on your single cell RNA-seq data. Specifically, you will learn how to: • Import your raw FASTQ or processed cell-matrix files. • Use pre-configur...

The updated ICH Q5A(R2) guidelines recommend next-generation sequencing (NGS) as the preferred approach for detecting adventitious agents. From cell line development and viral clearance studies to contamination tracing and product characterization, NGS-based tests outperform older assays in efficacy, sensitivity and reproducibility. This forms the basis for implementation by leading regulatory aut...

This is the second part of a series on how you can easily turn your ‘omics data into actionable insights using QIAGEN Ingenuity Pathway Analysis (IPA). Here, we’ll introduce you to the QIAGEN Knowledge Base and the different sets of results you can get from an IPA Core Analysis. You will learn: How to predict the activity of enriched pathways, regulators, diseases and more How to validate your res...

Now, you can access and share the interpretative power of QIAGEN Ingenuity Pathway Analysis (IPA) in an easy-to-consume format – without installing any extra software. IPA Interpret identifies and summarizes the biological themes in your results with the help of AI, creating a shareable, interactive report. You will learn how to: - Create an IPA Interpret report that can be easily shared with othe...

In this 90-minute training session, you will learn how to identify target mRNAs for your miRNAs of interest and associate them with pathways, diseases, biological functions, tissues and cell types.   Topics that will be covered include: How to analyze miRNA-seq datasets alone or both miRNA and corresponding mRNA datasets together How to use QIAGEN IPA without a dataset, using miRNA IDs Introd...

This is the first part of a series on how you can easily turn your ‘omics data into actionable insights using QIAGEN Ingenuity Pathway Analysis (IPA). Here, we'll focus on setting up your dataset for IPA upload and analysis. You will learn: The IDs, measurement types and formats that IPA supports How IPA uses your data for statistical tests and prediction scoring The different types and parameters...

As hereditary NGS testing grows more complex, clinical labs must interpret variants with greater speed and accuracy. This webinar introduces Franklin by QIAGEN, now integrated with HGMD Professional, combining AI-powered workflows and automated ACMG annotation with the leading expert-curated germline database. Together, they enable faster, evidence-backed interpretation, reduce manual review, and...

Accurate clinical interpretation of somatic cancer variants is critical for diagnosis and guidance of precision oncology treatment. Without shared standards, laboratories and clinical decision-support (CDS) systems have implemented independent approaches, leading to significant variability and highlighting a need for standardization.  Through a collaborative effort, ClinGen, the Cancer Genomi...

This hands-on workshop will cover a highly requested use case using OmicSoft Explorer and IPA Interpret, two new features that QIAGEN IPA* and OmicSoft customers can now access.   Specifically, the trainer will go over how to: Easily search for deeply curated high-quality 'omics datasets (RNA-seq, scRNA-seq, etc.) based on user-defined criteria (disease name, drug treatment, etc.) curated fro...

This webinar will introduce you to the Long Read Support plugin for Oxford Nanopore and PacBio sequencing reads in QIAGEN CLC Genomics Workbench. Learn how to: - Download and install needed plugins - Import data required for the analysis - Perform long read de novo assembly - Map reads to a reference and visualize an assembly - Use BLAST to investigate the contigs - Use additional long read tools:...

This 90-minute training session will show you how QIAGEN Ingenuity Pathway Analysis (IPA) helps visualize molecular intricacies and variations at multiple levels, such as transcriptome, proteome and metabolome. Through a series of brief technical vignettes, we will demonstrate how to: - Generate associations among molecular signatures obtained via integrating multi-omics data - Extract mechanisms...

The early stages of drug development are inherently high-risk; molecule screening, target evaluation and lead refinement can take years and cost millions of dollars – often have little to show for the effort. Indication expansion and drug repurposing can open new avenues of possibility, after careful evaluation of the relationships between the drug, its targets and the new disease context. These c...

In this video, we demonstrate the import and association of metadata with sample files.   https://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Metadata.html

In this video, we demonstrate how to view details of specific data points in plot views using the synchronized table view. See how you can easily access the list of genes that overlap in a Venn diagram for RNA-seq. This functionality is also available for other types of plots like track lists, expression browsers and volcano plots, to name a few.

Starting with CLC version 26, workflow control can be simplified using fork collections. https://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Fork.html#SECTION001425230000000000000

In this 90-minute training using Inflammatory Bowel Disease (IBD) public data from NCBI GEO through Omicsoft DiseaseLand, attendees will learn how to: • Rapidly query and identify public datasets that fit our search criteria • Discover and validate biomarker expression in disease tissue, different treatments, and response groups • Identify a list of biomarkers specific to responders vs non-respond...

In three separate 60-minute trainings, attendees will learn how to use basic expression analysis functionalities in QIAGEN OmicSoft OncoLand, DiseaseLand and OmicSoft Studio. QIAGEN OmicSoft Single Cell Land will also be discussed in OncoLand and DiseaseLand trainings, focusing on public single-cell data. Day 2: Biomarker discovery with QIAGEN OmicSoft DiseaseLand Leverage DiseaseLand’s repositori...

Single-cell gene expression analysis starting from either FASTQ or expression data is now supported by QIAGEN CLC Genomics Workbench Premium, the scalable cross-platform desktop software for NGS data analysis. In this webinar, we will re-analyze data from a study on transcriptional profiling of the mouse heart (Skelly et al., 2018), starting from FASTQ and ending with detecting sexually dimorphic...