Toxic History!

As one of the largest man made disasters in public health history, the discovery and realization of the disastrous effects of thalidomide in pregnant patients has paved a way to safe medication discovery and utilization. From this tragedy in modern medicine led new regulatory pathways, transparency in drug development, and expanded procedures to ensure therapeutic medication supply is not only eff...

Our long history of attempting to find a treatment for botulism is a winding road of discovery, setbacks, and the constant challenge of balancing risk and benefit. Through major outbreaks that seized the nation’s attention and the disruption of major wars, however, the spirit of science and humanity prevailed, bringing us a therapy to help us in our ongoing fight.

This talk will describe the early career of Albert Hofmann, his accidental discovery of the hallucinogenic properties of LSD-25, his legendary bicycle ride home from work during an LSD trip, and the legacy of his discovery.

The discovery of LSD and the subsequent psychedelic renaissance of the mid-20th century hold ample space in history books, but Albert Hofmann didn’t discover the first mind-altering chemical. At the turn of the 20th century, natural psychedelics’ ancient power crossed continents to shape both cultural and technological development.

Want to know what toxic medicine has killed thousands of people? Why outbreaks keep happening? And how it started the modern FDA? Listen Dr. Prosser's Toxic History episode to find out!

In the 1920s and 1930s, radium was an exciting new material. It was used to illuminate watch dials in the dark, treat tumors, and also as a primary ingredient in quack medical remedies. This is the story of Radithor, a fake medicine containing radium.

The Salem witch trials of the early 1690s were the most notorious and lethal witch hunt in American history. At the heart of the trials, the Village of Salem was a town at its boiling point, but the complex political and social factors at play still seem insufficient to explain the happenings that ultimately transpired. Could it be that the affliction at the heart of Salem, the proximate cause of...

Toxicology is full of treatments which are poorly supported by literature. Many of those treatments originated over 100 years ago. If you think data are bad now, we invite you to see what treatments were like in the past – drawn from the pages of multiple historical toxicology textbooks.

Dioxins are a category of persistent organic pollutant (POP), with a long history of human exposure and serious adverse health and environmental effects. Where did this forever chemical come from, and how did it end up in the dinner of Ukrainian President Viktor Yushchenko in 2004? Join us as we discuss the long-lasting legacy of this class of compounds that was banned in 2001, but remains forever...

Springtime at the turn of the 20th century promised rebirth, hope, and prosperity in America. But in northern Michigan, a twisted nightmare was consuming an idyllic community. An infant was found deceased in a crib, the mother succumbing within the next hour, and the father only days later. Some feared a curse, others speculated a contagion. An intrepid duo of sheriff and attorney left no stone un...

Join Dr. Marlis Gnirke on a “trip” to 1960s California discussing a different kind of acid, one at the intersection of human toxicology, veterinary toxicology, and classic cinema.

Dr. Sukhi Atti discusses the history of the release of nerve agent VX in Skull Valley, Utah.

Dr. Laurén Murphy discusses the history of physostigmine - from bean to medicine.

Dr. Stephanie Weiss describes the history of the fentanyl epidemics in the USA.

Dr. Peter Akpunonu discusses the history of the toxic grain disaster in Iraq.

Dr. Alan Woolf discusses the toxicological history of the Chicago Tylenol Murders.

Dr. Alex Harding describes the history of "The Toxic Woman."

Dr. Sing-Yi Feng discusses the toxic history of classical music with guest host Dr. Keahi Horowitz.

Dr. Joshua Bloom tells the history of the Nobel-prize winning research that led to the cure for Beri Beri.

Dr. David Loughran discusses the history of the Angel Makers of Nagyrev

Dr. Zane Horowitz tells the toxic history of the Antarctic Adventure of Douglas Mawson

Dr. Noah Berland discusses the history of the Minamata Bay Disaster.

Dr. Anita Mudan tells the history of the Teacup Poisoner.

Dr. Joseph Clemons tells the history of the The Goiânia Incident.

Dr. Laurén Murphy tells the toxic history of King Mithradates.