The Stem Cell Podcast

Guest: Dr. William Dunworth is an Account Manager at STEMCELL Technologies and will be talking about his transition from bench to industry, and what advice he has to offer in terms of careers in stem cell science beyond the bench. Featured Resource: Celebration of Science Resources and Links Study on Gun-Policy Effects Finds Important Gaps in Existing Research – One of the largest-ever studi...

Guest Dr. Justin Ichida is the Assistant Professor in the Department of Stem Cell Biology and Regenerative Medicine at the University of Southern California.  Dr. Ichida’s laboratory creates  in vitro  models of human neurodegenerative diseases by converting patients’ cells into disease-affected neural cells. Featured Resource: Madeline Lancaster on Brain Organoids: Modeling Human Brain Developmen...

Guest Dr. Fernando Camargo is a Principal Investigator at Boston Children’s Hospital and Professor in the Department of Stem Cell and Regenerative Biology at Harvard University. Dr. Camargo’s laboratory’s ultimate goal is to understand the signals that regulate adult stem cell maturation and tissue regeneration and has a strong interest in studying the cellular and molecular biology of hemat...

Guest Dr. Kapil Bharti is a Principal Investigator at the National Eye Institute at the NIH.  His work involves performing translational research on degenerative eye diseases using induced pluripotent stem cell technology. Dr. Bharti’s group uses this technology to develop in vitro disease models to study patient-specific disease processes, to set up high throughput drug screens, and to develop ce...

Guest Dr. April Pyle is an Associate Professor in the Department of Microbiology, Immunology and Molecular Genetics at the University of California, Los Angeles (UCLA). She is also a member of the Eli and Edythe Broad Stem Cell Center, the Center for Duchenne Muscular Dystrophy and the Jonsson Comprehensive Cancer Center at UCLA. Dr. Pyle’s lab uses multi-disciplinary approaches to study hum...

Guest Dr. Michele De Luca has been involved in epithelial stem cell biology aimed at clinical applications in regenerative medicine for over 20 years. He joins the show to discuss his work and latest groundbreaking paper published in Nature. Featured Resource: Growing Organoids from Stem Cells Wallchart Resources and Links New Tax Plan Closer to Passing and Impacting Science – If the new tax plan...

Guest Dr. Leigh Turner is an associate professor in the center for Bioethics at the University of Minnesota. Turner’s research addresses ethical, legal, and regulatory issues associated with clinics engaged in direct-to-consumer marketing of unproven and unlicensed cell-based interventions. Dr. Turner is an author of numerous publications including a recent paper in Cell Stem Cell along with The S...

Guest The Stem Cell Podcast and STEMCELL Technologies introduce the first interview in a new series called, “Alternative Science Careers.”  For the first part of this series, we are pleased to interview the host of our very own Stem Cell Podcast, Dr. Kiki Sanford. Featured Resource: Organoid Research Resources and Links In New Budget, Graduate Student Taxes Could Go Up – This editorial...

Guest Dr. Chad Cowan is a Principal Investigator and Associate Professor in Department of Stem Cell and Regenerative Biology at Harvard University. Chad joins the hosts to talk about CRISPR and its uses with stem cell biology to study disease. Featured Resource: Investigating Metabolic Disease with Human Pluripotent Stem Cells Webinar Resources and Links E-Cigarettes Can Lead Teens to Higher Smoki...

Guest Assistant Professor of Medicine at the University of North Carolina Medical Center, Catherine Coombs, talks to us about her work and her recent paper in Cell Stem Cell on the subject of clonal hematopoiesis. Featured Resource: Targeting Self-Renewal Function in Normal Hematopoietic and Leukemic Stem Cells Webinar Resources and Links An Estimated 124 Million Boys and Girls Are Now in the High...

Guest Sierra Marable is a graduate student in the Molecular and Developmental Biology Graduate Program at Cincinnati Children’s Hospital Medical Center. She previously worked at the Post-Baccalaureate Research Education Program (PREP) at the Wake Forest School of Medicine in North Carolina where she became interested in stem cell research while researching induced pluripotent stem cells as a...

Guest: Dr. Jack Parent is a professor of neurology, director of the Neurodevelopment and Regeneration Laboratory, and co-director of the Comprehensive Epilepsy Center in the University of Michigan Medical School. Featured Resource: CloneR™ Defined Supplement for Single-Cell Cloning of Human ES and iPS Cells Resources and Links Potential Role of Intratumor Bacteria in Mediating Tumor Resistance to...

Guest: For the interview portion of the show of our 100 th episode, we welcome Kevin McCormack from the California Institute of Regenerative Medicine, or CIRM, to talk about all of CIRM’s progress, past, present, and future…CIRM was created in 2004 to translate stem cell discoveries into therapies, and we will talk to Kevin about the progress this funding has made. Featured Resource: mTeSR™1...

Guest: Dr. Chandan Sen is Professor and Vice Chair of Research, Department of Surgery at The Ohio State University Medical Center.  Dr. Sen’s program is focused on tissue injury and repair. His group works across small and large animal models, to human and patient-based research. Resources and Links Embryos Kill Off Male Tissue to Become Female – A protein called COUP-TFII is necessary to eliminat...

Guest: Dr. Dustin Wakeman is Senior Research Scientist at RxGen and Adjunct Assistant Professor at Yale School of Medicine.  Dr. Wakeman focuses his career on determining the long-term therapeutic value of stem cell therapy in neurodegenerative disorders. His interests include stem cell-based therapeutics, disease modeling, neural transplantation, and morphological and molecular changes in aging a...

Guest: Dr. Mark Tomishima is an Associate Laboratory Member and Sloan Kettering Institute Stem Cell Research Facility Manager. Mark joins us to talk about all things stem cells, including his latest published work on standardizing protocols that start with pluripotent stem cells. Featured Resource: FreSR™-S Animal Component-Free Medium for Freezing ES and iPS Cells as Single Cells Resources and Li...

Guest: Dr. Robert Hancock is a Professor of Microbiology and Immunology, UBC, and a Canada Research Chair in Health and Genomics. Bob has published more than 660 papers and reviews, and has 50 patents awarded. The fundamental interest of Dr. Hancock and his laboratory is in designing new therapeutic strategies to treat infections in the light of increasing antibiotic resistance coupled with a dear...

Guest: Dr. Darrell Kotton is a David C. Seldin Professor of Medicine and works as the Director in the Center for Regenerative Medicine of Boston University and Boston Medical Center. Dr. Kotton’s research focuses on stem cell biology and gene therapy related to lung injury and repair. Dr. Kotton’s laboratory currently utilizes several stem cell populations, including bone marrow-derived stem cells...

Guest: In this episode, we welcome Drs. Shahin Rafii and Raphael Lis. Dr. Rafii is director of the Ansary Stem Cell Institute, chief of the Division of Regenerative Medicine, and the Arthur B. Belfer Professor at Weill Cornell Medicine. His lab investigates stem cell biology and angiogenesis using in vivo mouse models. Dr. Lis who was the first author on their recent Nature paper and is an Instruc...

Guest: Dr. Clive Svendsen is the Director of the Board of Governors Regenerative Medicine Institute and Professor of Biomedical Sciences at Cedar Sinai Medical Center. One focus of his current research is to derive cells from patients with specific disorders, which can then be “reprogrammed” to a primitive state and used as powerful models of human disease. The other side of his research involves...

Guest: Dr. Farshid Guilak, a Professor in the Department of Orthopaedic Surgery at Washington University and Director of Research for the Shriners Hospitals for Children. His laboratory is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem-cell therapies. Featured Resource: Mesenchymal S...

Guest: In this episode, we bring you Drs. Rick Horwitz and Graham Johnson from the Allen Institute for Cell Sciences. They discuss the Allen Cell Explorer, a 3-D cell library created using induced pluripotent stem cells. Featured Resource: STEMdiff™ Trilineage Differentiation Kit Resources and Links A March for Science Happened – Scientists had to engage and take their demands to political leaders...

Guest: Dr. Alysson Muotri is a Professor at the School of Medicine, University of California in San Diego. His research focuses on modeling neurological diseases, such as Autism Spectrum Disorders, using human induced pluripotent stem cells. His lab has developed several techniques to culture human neurons and glia for basic research and drug-screening platforms. Most recently he and his group pub...

Guest: Dr. Fabio Rossi is a Professor at the Department of Medical Genetics and Director of Biomedical Research Centre at the University of British Columbia. He joins us to discuss the role of mesenchymal stem cells in regeneration and fibrosis in vivo . Featured Resource: CloneR™ Defined Supplement for Single-Cell Cloning of Human ES and iPS Cells Resources and Links New Steel Modeled After Bones...

Guest: For this episode’s interview, we bring on Dr. Shawn Hingtgen, Assistant Professor at the Department of Molecular Pharmaceutics at UNC Eshelman School of Pharmacy, and Dr. Matthew G. Ewend, Chair of the Department of Neurosurgery at UNC School of Medicine. Dr. Hingtgen’s research focuses on utilizing molecular imaging to characterize and validate novel stem cell-based targeted therapeutics f...