The Human Upgrade: Biohacking for Longevity & Performance

In this episode of The Human Upgrade , Dave Asprey talks to Chris Fields, Chief Science Officer at Applied Food Sciences, about the game-changing nootropic AmaTea® Max. They discuss how this natural extract of guayusa delivers long-lasting energy and mental clarity, backed by science and sustainable practices. Learn how AmaTea® Max is revolutionizing cognitive performance, especially for athletes...

In this episode of The Human Upgrade , Dave Asprey welcomes Dr. Jamil Zaki, a professor of psychology at Stanford University and the director of the Stanford Social Neuroscience Lab. Dr. Zaki discusses the critical intersection between empathy, cynicism, and hope, exploring the impacts of negativity bias, cynicism in modern society, and how we can rewire our brains to become more hopeful. Drawing...

In this special Asprey Archive episode from 2023, we talk to Shaahin Cheyene. Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being...

In this episode of The Human Upgrade , vision expert Claudia Muehlenweg and strength coach Dave Mark Bell join Dave Asprey to explore the intersection of natural vision improvement and physical performance. Claudia shares her expertise in the Bates Method and techniques like palming, which help restore clarity and reduce eye strain. Dave Mark Bell highlights how physical training and focus can enh...

In this enlightening episode of The Human Upgrade , Dave Asprey is joined by polymath and visionary Robert Edward Grant. Known for his groundbreaking work in fields ranging from mathematics and cryptography to art and consciousness, Robert shares insights into how his diverse expertise has shaped his understanding of the interconnectedness of science, art, and spirituality. The conversation delves...

In this episode of The Human Upgrade , Dave Asprey is joined by Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Seraphina Therapeutics, to explore the groundbreaking discovery of C15, also known as Pentadecanoic acid. This episode uncovers how Dr. Venn-Watson's work with aging dolphins in the U.S. Navy led to the surprising revelation that C15 is an essential fatty acid, m...

In this episode of The Human Upgrade , four experts—Dr. Molly Maloof, Aggie Lal, Dr. Justin Lehmiller, and Dr. Mary Claire Haver—discuss personalized biohacking strategies for women, focusing on hormonal balance, mitochondrial health, sexual wellness, and optimizing energy through cycle syncing and stress management.  Dr. Molly Maloof , a health optimization expert and author, delves into the...

In this insightful episode of The Human Upgrade , Dave Asprey sits down with Dr. Mary Newport, a renowned expert in lipid metabolism and brain health, to discuss the critical role of fats in preventing Alzheimer's disease and promoting cognitive longevity. Dr. Newport, author of the book Clearly Keto for Healthy Brain Aging and Alzheimer’s Prevention , shares her deep knowledge of how different fa...

On this special Upgrade Spotlight episode of The Human Upgrade, you'll dive into the cutting-edge world of ketones and their profound impact on brain function and overall health with Michael Brandt, CEO and Co-founder of HVMN. Discover how Ketone IQ can fuel your cognitive abilities, enhance physical performance, and support your body's resilience under stress.  Michael unpacks the science be...

In this special "Best Of" episode of The Human Upgrade , four leading experts delve into the hidden dangers of mold, environmental toxins, and their profound effects on your health and well-being.  Brian Karr , an indoor environmental consultant and co-founder of We Inspect, discusses the impact of mold exposure and offers practical tips for detecting and remediating mold in your home. He hig...

In this episode of The Human Upgrade, recorded live from Costa Rica, Dave Asprey sits down with Dr. Vince from the Regenerative Medicine Institute (RMI) to delve into the groundbreaking world of regenerative medicine. Dr. Vince shares his expertise on how advanced therapies, including stem cell treatments and personalized regenerative protocols, are paving the way for enhanced longevity and optima...

In this special "Best Of" episode of The Human Upgrade , four leading experts share their insights on skincare, skin health, and cutting-edge techniques to enhance your appearance and overall well-being.  Rachel Varga , a Board-Certified Aesthetic Nurse Specialist and recognized expert in skin rejuvenation, discusses the importance of biohacking for maintaining vibrant, healthy skin. She high...

In this episode of The Human Upgrade, Dr. Manoj Doss, a neuroscientist at the University of Texas at Austin Dell Medical School, explores the fascinating intersection of psychedelics, memory, and cognitive enhancement. Drawing from his extensive research, Dr. Doss dives into how psychoactive substances like THC, ketamine, and psychedelics can alter memory formation, consolidation, and retrieval. H...

In this episode of The Human Upgrade , Dr. Christy Sutton delves into the intricate relationship between iron, zinc, copper, and other essential minerals that play a crucial role in longevity and overall health. Drawing from her book, The Iron Curse , Dr. Sutton shares insights into how mineral imbalances can lead to conditions like iron overload, anemia, and other health issues, and how these imb...

In this episode of The Human Upgrade, renowned opera singer Renée Fleming explores the powerful connection between music, neuroscience, and longevity. Renée shares her journey with stage fright and somatic pain, revealing how she overcame these challenges to achieve greatness in her field.  You'll learn about the impact of music on the brain, its role in enhancing cognitive function, and its...

In this episode of The Human Upgrade, Dr. Tracy Gapin, a board-certified urologist, men's health expert, and founder of the GAPIN Institute, discusses the critical role of testosterone in health. He addresses the alarming decline in testosterone levels globally, the symptoms of low testosterone, and its impact on male behavior.  You'll gain insights into natural methods to boost testosterone,...

In this special episode of The Human Upgrade , you will gain insights from four experts on brain health, memory, attention, and cognitive enhancement.  Dr. Daniel Amen , a renowned psychiatrist and brain health expert, discusses the importance of daily practices for brain and mental health. He shares strategies to improve brain function and prevent cognitive decline.  Jim Kwik , a brain...

On this special Upgrade Spotlight episode of The Human Upgrade, you'll explore the science of NAD and its vital role in your cellular health with Dr. Nichola Conlon from Nuchido Laboratories. Learn how NAD supports energy production, cellular repair, and longevity. Dr. Conlon breaks down the latest research on NAD, explaining why levels decline with age and how to naturally boost them without expe...

In this special episode of The Human Upgrade , you will gain insights from four fitness and health experts on understanding muscle, how to grow muscle, exercise effectively, and recover properly.  Dr. Gabrielle Lyon , a functional medicine physician, emphasizes the critical role of skeletal muscle as an organ of longevity. She explains how muscle health impacts overall well-being and offers s...

In this episode of The Human Upgrade , entrepreneur and philanthropist Naveen Jain discusses groundbreaking insights into the differences between oral and gut microbiomes and the impact of oral bacteria on overall health. You’ll learn why traditional mouthwash might be harmful and explore the Apollo Group's role in health mentoring and collaboration.  Naveen shares his decade-long dedication...

In this episode of The Human Upgrade, Dr. Robert Lufkin delves into the misconceptions in medical education and the vital importance of metabolic health. He discusses how outdated practices in medical training can negatively impact public health and shares insights on the critical role of personalized nutrition in enhancing metabolic health.  Dr. Lufkin explores the connection between hormone...

In this episode of The Human Upgrade, Dr. Peter Ballerstedt, a leading expert in ruminant animal agriculture, discusses the essential role of ruminant animals in sustainable farming. You'll learn about the critical importance of animals like cows and sheep in maintaining soil health, supporting ecosystems, and providing high-quality nutrition.  You’ll also learn about the myths surrounding li...

In this special Asprey Archive episode of The Human Upgrade you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey.  Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. In this episode from 2022, he thoughtfully balances each passion through his work as an Alzheimer’s advocate...

In this episode of The Human Upgrade, Harry Massey joins the show to delve into the fascinating field of bioenergetics and its profound impact on health and healing. Discover how bioenergetics, the study of energy in living systems, can revolutionize your approach to wellness by enhancing the body's energy and control systems.  Harry shares his journey from battling chronic fatigue syndrome t...

In this episode of The Human Upgrade, Dr. Neil Nathan joins to explore the intricate world of toxic mold, Lyme disease, and sensitivity-related illnesses. You'll discover the profound impact of these environmental toxins on your health and the innovative methods for diagnosing and treating them.  Learn how mold and Lyme disease can disrupt your body's systems, and get practical strategies for...