Nicolas Verhoeven
Physionic
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic! JOIN MY PHYSIONIC SOCIAL NETWORKJoin my Community [It’s Free!]: https://bit.ly/PhysionicCommunityJoin the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsidersHIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H WHERE ELSE IM ACTIVE:Email: http://bit.ly/2AXIzK6YouTube: http://bit.ly/2JUjXVtInstagram: http://bit.ly/2OBFe7i
Autor
Nicolas Verhoeven
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Podcast-Website
Neueste Folge
20. Apr 2026
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Ketogenic Diet & Ketosis leads to Heart Cell Death [Study Breakdown] 17.03.2021 39:24
In this episode, I take us on a brief breakdown of a study looking at the ketogenic diet and its impact on heart cell death, heart size, and mitochondrial content. Some intriguing, potentially alarming, results here, but we'll see what interpretations we can really make on this data - dive in with me! Study: https://www.nature.com/articles/s41392-020-00411-4 Books, Courses, and Hire Me: www.physio...
Burning More Fat DOES NOT mean losing more BODY FAT 10.03.2021 33:27
In this episode, I attempt to make it as clear as possible, by comparison of high fat/keto to high carbohydrate diets and how they differ in their ability produce body fat loss, although one promotes greater fat burning/oxidation. Video Podcast (available at 10am ET): https://youtu.be/Ns0tXvLI-OI Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instag...
Metabolic Flexibility: Switching from Carbs to Fat, and Back Again 03.03.2021 25:16
In this episode, I give a bit of a higher level view on metabolic flexibility - what is it? Why is it important? Instances of it? How to improve it? That's all covered in this podcast - enjoy! Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
Does Water Fasting increase our Mitochondria? 17.02.2021 17:14
In this episode, I briefly cover certain aspects of a study that looks into how effective fasting, specifically multi day water fasting, affects our mitochondrial content in our cells (muscle). Video Podcast: https://youtu.be/KMU1OcGjjLw Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
I ran an Experiment on Myself [Muscle Maintenance] and Your Questions Answered 10.02.2021 28:40
In this episode, I cover more detail on an experiment I decided to try on myself over the last 10 months wherein I try to maintain my muscle with minimal effort. I answer questions from 10 people who wrote questions out on how I pulled it off, as well as other questions related to fat loss and muscle perseveration. Video being Discussed [I Ran an Experiment on Myself]: https://youtu.be/qtim_tXkVoQ...
Mutations that affect Muscle Fusion 03.02.2021 48:15
In this podcast, we'll be going over a presentation I gave in one of my courses on Muscle Biology - specifically, how certain mutations in a gene can impede muscle cells' ability to fuse, and on top of that, why some people survive it and why others do not. Study: https://www.nature.com/articles/ncomms16077 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2Pl...
You Can't Have it All [Lifespan vs Health span] 27.01.2021 22:43
There is no human condition wherein you will be at peak form in multiple areas. Much like the idea of the generalist vs the specialist - your body can't be a specialist in all ways, and in the same vein, there is no diet that will be the "ultimate" diet that will help you achieve peak-ness in all areas. The discussion of lifespan vs health span is a great example of that, as well as the idea of gr...
Fasting and Calorie Counting: Which stimulates Hunger Hormones? [Leptin, MSH, AgRP] 20.01.2021 21:28
In this content, I dive into a study looking into three hunger related hormones and the effect water fasting and calorie counting have, in obese and lean individuals, on three hunger hormones - leptin, melanocyte stimulating hormone (MSH), and Aguiti Related Protein (AgRP). Does fasting stimulate these hormones or does calorie counting? Does obesity play a factor? Find out! Study: https://pubmed.n...
Fractalkine: A marker for Alzheimer's and Neuroinflammation 13.01.2021 32:43
In this episode, I discuss a molecule I ran across when listening to the Joe Rogan Experience. This molecule, known as fractalkine, has some unique characteristics and potential implications in a series of different diseases and brain related health outcomes - mostly related to inflammation in the brain. Review: https://pubmed.ncbi.nlm.nih.gov/26084002/ My Creatine Book and Course: http://bit.ly/3...
Three UNKNOWN Benefits of Creatine [Muscle, Brain, and Inflammation] 06.01.2021 22:14
In this episode, we briefly discuss three ways that creatine positively affects us in muscle, the brain, and inflammation. I also introduce my first paid content that I spent most of 2020 working on, as well as a new website for your viewing pleasure - it was a busy 2020 for me! Creatine Book and Course: https://www.physionic.org/booksandcourses Books, Courses, and Hire Me: www.physionic.org...
ASP: The Ketogenic Fat Storage Hormone 30.12.2020 28:51
In this episode, I go into a bit more detail on a topic I've just started releasing content on (in video form). This subject is on a hormone that also leads to fat storage, much like insulin, yet many keto espousing gurus either ignore or are not aware of it; this is convenient, since this hormone is stimulated by fat consumption, not carbohydrate consumption (the exact anti-thesis to insulin). Bo...
Chrono nutrition: Intermittent Fasting improves Insulin Sensitivity INDEPENDENT of Calories 16.12.2020 30:51
In this episode, we'll be diving head long into a study investigating the first slice of "chrono nutrition" on Physionic. I love this study, because they do several things really well and give us some clear answers regarding intermittent fasting and its impact on insulin sensitivity *independent* of calorie intake (finally!). Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528549/pdf/nqaa192....
Three Mechanisms of Muscle Growth 09.12.2020 32:54
In this podcast, I decided to jump into an area I've created a decent amount of isolated content and put it into one place. I go into a bit of depth, but not complete depth into three mechanisms of muscle growth - from the classic "muscle damage" to metabolic stress. Knowing this information can easily help us understand how to create training programs that aren't centered around old fashioned thi...
Nutrition for Depression: Obesity, Epigenetics, and Tryptophan (yes, the stuff in turkey) 02.12.2020 30:26
In this episode, we'll be diving into our third and final part of our "Nutrition on Depression" podcast wherein we'll be touching on depression's link in obesity, epigenetics, and the amino acid tryptophan (the same stuff found in turkey, and many other foods). Hopefully you find some, if not all, the information useful and informative. If you'd like to see the visuals, check out the video version...
Nutrition for Depression: The HPA Axis, Brain Derived Neurotrophic Factor, and More [Part 2] 25.11.2020 47:50
In this episode, we continue our dive into these different nutrients and nutritionally linked reasons why people have worsening depression and what to do against it, nutritionally. This is part 2 of a 3 part podcast series discussing nutrition and its relationship to depression. I'll go into the microbiome, cortisol release from the HPA axis, and BDNF on brain cell growth. Study: https://www.natur...
Nutrition on Depression: Nutrients that Help [Part 1] 18.11.2020 58:25
In this episode, I begin with part 1, wherein we'll be discussing how depression is linked to inflammation, mitochondrial dysfunction, and oxidative stress, as well as several nutrients that can help reduce these effects negatively affecting mental health. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit....
Fasting on Skin Health & Skin Aging: A Review 11.11.2020 42:35
In this episode, I'll be trying my best to make sense of a pretty "all over the place" scientific review that attempts to make sense of how fasting (and calorie deficits) affect skin health, as well as aging. Video Version: https://youtu.be/ihV7hOhAk58 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK...
Caffeine: Does it make us less insulin sensitive? 04.11.2020 39:56
In this episode, we dive into a study that investigates the effect caffeine has on insulin sensitivity, but also on a few other parameters, like blood pressure, catecholamines, and free fat. Study: https://care.diabetesjournals.org/content/25/2/364.full-text.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit...
Creatine on Fat Metabolism, Thermogenesis, ft. Alec Chaves 28.10.2020 1:07:59
In this episode, I have the absolute pleasure of welcoming a good friend of mine back to the podcast to discuss a paper he picked out looking at a unique way that creatine affects our fat cells - specifically, the mitochondria within fat cells. Creatine Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656041/ Alec's Podcast (Physiology Forum): Apple: https://podcasts.apple.com/us/podcast/the-p...
Women vs Men: Who Gains Muscle Strength Faster? 21.10.2020 29:39
In this episode, we dive into an extremely simple study that investigates how quickly men and women, compared against one another, gain muscle strength from a resistance training program. Not only that, it touches on some interesting perspectives related to hormones and how the lack of testosterone in women may not be as detrimental as one might imagine - tune in and find out! Study: https://www.n...
10 Day Water Fast INCREASES Inflammation, but is that bad? 14.10.2020 41:57
In this podcast, we'll be going over a study that touched on an interesting discovery between fat cells and our immune system when a person undergoes an extended (10 day) water fast. Study: https://reader.elsevier.com/reader/sd/pii/S2212877820301563?token=8C7127DDF72DF25D84C3810C2A6673547BFB183F9FA75E6692EA9472DCC7CC12A193097F7212AC3D993955B07CAA1405 Books, Courses, and Hire Me: www.physionic.org...
Does Saturated Fat increase Cholesterol and damage your Liver? 07.10.2020 57:57
In this episode, I do a deep dive into a study that finally tries to answer if saturated fat increases our cholesterol levels, independent of weight gain. Not only that, it also investigates the impact it has on the liver in terms of fatness - does it cause fatty liver disease? Study: https://academic.oup.com/jcem/article/104/12/6207/5540968 Books, Courses, and Hire Me: www.physionic.org YouTube:...
Alternate Day Fasting on Cholesterol, Muscle, and Fat-centric Hormones 30.09.2020 45:20
In this episode, I'll be taking you through a study on alternate day fasting and its affects on cholesterol, fat, muscle, and three unique hormones - all in people without cardiovascular issues, which makes this study that much more unique. Study: https://onlinelibrary.wiley.com/doi/10.1038/oby.2010.54 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB...
A Light Review of Body Weight "Set Point" Theory 23.09.2020 53:14
In this podcast, I brush across a variety of concepts and information related to the hypothesis of "body weight set point" that espouses the idea that the body sticks to roughly the same set point in body weight when we attempt to change our weight, the body fights against that imposed change - why? What mechanisms and reasons might there be? Is there a better theory? Study: https://www.ncbi.nlm.n...
The Consequences of Extreme Dieting & Low Body Fat 16.09.2020 54:02
In this episode, I'll be walking us through a case study that recently released on a natural bodybuilder that was followed and measured by researchers for 12 months. They wanted to know how extreme dieting to low single digit body fat would affect testosterone, thyroid hormone, muscle mass, metabolism, and more, and if there were any negative effects, how long would it take to recover? Study: http...
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