Mayo Clinic School of Continuous Professional Development
Mayo Clinic On Human Optimization
The bar for human performance is higher than it’s ever been. As a result, we all feel the need to do MORE. At the same time, we are becoming increasingly aware of the value of sleep, rest, recovery, and wellness. Accordingly, we also feel the need to do LESS. If you’re like most people, it can be challenging to reconcile this conflict of feeling the need to do MORE and LESS simultaneously, and that is likely contributing to high rates of burnout and decreased performance. So how do we reconcile these seemingly competing desires? That is where Human Optimization comes in. Human Optimization is...
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Mayo Clinic School of Continuous Professional Development
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Neueste Folge
4. Nov 2026
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E72 No such thing as a stress-free life. Build resilience. 04.11.2026 58:26
Stress is everywhere in life. It can’t be avoided, and in fact, for most of us, living totally stress-free actually isn’t desirable. Doing hard things can give us an incredible sense of purpose and accomplishment. But too much stress can make us feel overwhelmed, paralyzed and incapable of handling even the smallest tasks. So how do we learn to increase our stress tolerance so we...
E71 What is human optimization? 21.10.2026 50:38
For a lot of people, being “ambitious” is kind of synonymous with “doing more.” Work more hours, make more money, win more awards. But then, as we teeter on the edge of burnout, we also get this message to “do less” — make time for relationships, take care of your body, sleep. Which just feels like another “more.” So how are we supposed to achieve more, while also doing “less”? This episode, we’re...
E70 Human flourishing: What it is and how to do it 07.10.2026 44:07
People like easily quantified measures of success – money, degrees, awards, followers. They’re simple and straightforward. The more you have, the better you’re doing. At least in theory. Reality is a little more complicated. You can be financially secure but lonely. Highly productive but purposeless. Successful but depleted. So how do we go from looking good on paper...
E69 Inspiring others: How to help people rise 23.09.2026 38:38
Modern workplaces love their KPIs, deadlines, deliverables — anything we can use to quantify success. And while shareholders might get all fired up when they see those numbers move in the right direction, for the people doing the work, it really isn’t enough. We need more than a number and a target to do our best work, stay motivated, and prevent burnout. (And no, a boss peering over our shoulder...
E68 Quiet the inner critic: Mastering self-compassion 09.09.2026 50:25
Ambitious people often credit their success to a strong inner critic. They take pride in “staying hungry” and talk about complacency like it’s an existential threat. But that same voice can steal the joy from our happiest moments – moments in life where we should feel proud and accomplished, but all we can see are the little missteps we took along the way. Or the things we ...
E67 Forward-thinking leadership: Stop reacting, start leading 26.08.2026 47:37
Do you feel that you’re creating the future for yourself and your team? Or are you spending your time just reacting to the crisis of the day? While it’s critical to keep the ship from sinking, we also need to do some work to ensure that we’re steering the ship in the right direction. This requires forward-thinking. This episode, we’re joined by Coen A. Wijdicks, Ph. D. He holds a Ph. D. in biomedi...
E66 Become the CEO of your own health with Dr. Shah 12.08.2026 40:27
Everyone knows that our health is fundamental to our whole experience of life. So why does it always seem like it’s the first thing to get deprioritized when life gets busy? And when we do try to make it a priority, why does it feel like our efforts don’t lead to meaningful change? This episode, we’re joined by Dr. Darshan Shah. He’s a surgeon, author, entrepreneur, and host of his own podca...
E65 The mental game of physical fitness 29.07.2026 49:05
You don’t need anyone to tell you that working out is hard. That’s the whole point. But for many of us, the hardest part isn’t physically lifting the weights or running the laps. It’s getting to the gym in the first place. It’s knowing that we can do hard things. It’s staying motivated to keep working at it, even when...
E64 Building trust: A powerful performance multiplier 15.07.2026 51:31
New relationships are hard for a reason – no trust. You’re starting from scratch with no common understanding, no established shared goals, or history of goodwill. Everyone’s feeling vulnerable. But also suspicious. It feels hard to take risks or even just relax and be yourself. So, how do we get past the awkwardness and start buildin...
E63 A framework for understanding good leadership 01.07.2026 43:31
Everyone loves a good leader. But they’re often held up as these singular examples of success, vision, inspiration, and perseverance. And we struggle to learn from their stories and distill them into a practical, repeatable blueprint for good leadership. This episode, we’re joined by Dr. James Hebl, Medical Director for Leadership and Talent Development at Mayo Clinic and a certified executive c...
E62 Self-care for busy people: Productivity demands recovery 17.06.2026 54:24
Self-care is one of the most commonly used, but poorly understood concepts today. For some, it brings to mind indulgence, luxury, or performative wellness culture. For others, it feels selfish, soft, or unrealistic. However, self-care, when done properly, helps fuel us to be our best selves and will maximize performance gains and achievement. Our expert guest for this episode is Dr. Amy Oxentenk...
E61 How to define your personal values 03.06.2026 46:12
Life offers plenty of nice, concrete, mostly attainable goals for us to chase and boxes to check – good job, life partner, maybe a house, maybe kids. But that’s also the classic recipe for a midlife crisis: you work your butt off to get a bunch of those boxes checked only to find yourself exhausted and unfulfilled. Or wondering, “Now what?” So, how do we ground our goals to make sure we’re puttin...
E60 Unlocking Potential: The Art of Talent Development 20.05.2026 48:33
Imagine: you get yourself a sweet new sports car, hop in for your first drive, only to realize you have no idea how to drive stick. So you drive around town in first gear, going super slow, making tons of noise, stalling out at every stop sign. You finally make it home, hop out and proclaim, “This car’s a piece of junk!” Well, that’s the challenge we face with talent development, where the ceiling...
E59 The Sleep Paradox: Why Trying Harder Makes It Worse 06.05.2026 43:15
Why is it that the more we think about falling asleep, the harder it becomes? Our mindset around sleep plays a huge role in our ability to fall asleep, the amount of sleep we get and the quality of that sleep. So how can we use our mindset to our advantage? This episode, we speak with Bhanu Kolla, M.B.B.S., M.D., the co-author of the Mayo Clinic Guide to Better Sleep. He’s also a professor of psy...
E58 Being in Charge vs. Being a Leader 22.04.2026 37:30
Just having a title that sounds authoritative doesn’t make someone a leader. And you don’t have to be a CEO to lead, either. So what actually inspires people to take action? In this episode, we’re joined by Thom Mayer, M.D., to explore how to stop waiting for authority and start leading. Dr. Mayer is medical director for the NFL Players Association and author of the book Leadership Is Worthless, b...
E57 The State of Flow: How to Maximize 08.04.2026 40:22
Hopefully, you’ve experienced getting so absorbed in work or an activity you enjoy that you lose track of time. We tend to be most productive in what is often called a “state of flow.” When harnessed effectively, flow can act like a superpower for personal fulfillment and progress. To help us better understand and maximize moments of flow, we’re joined by Biju Samkutty, chief operating officer of...
Tomorrow's Cure - When Algorithms Meet Empathy: The Future of Patient-Centered AI 01.04.2026 49:47
Today, we are sharing an episode from our sister podcast Tomorrow’s Cure. Produced by our Mayo Clinic colleagues, this chart-topping and Ambie Award-finalist podcast explores the future of medicine – from the rise of chronic disease and autoimmune disorders to innovations in AI, 3D bioprinting, and cancer research. In this specific episode, you’ll hear from Mayo Clinic physician leader Dr. Anjali...
E56 How to Get More Mileage from Your Brain 25.03.2026 54:14
How often do you feel that your brain is functioning at its highest level? If you are like most of us, it’s not as often as you would like. Given the high-pressure world we live in, it’s critical for us to ensure our brain is firing on all cylinders, as often as possible. To make that happen, we need to help our brains be more efficient. Just like mileage on a car, we want to optimize the mileage...
Tomorrow's Cure - 3D Bioprinted Skin: Breakthroughs in Regenerative Medicine 18.03.2026 40:47
Today, we are sharing an episode from our sister podcast Tomorrow’s Cure. Produced by our Mayo Clinic colleagues, this chart-topping and Ambie Award-finalist podcast explores the future of medicine – from the rise of chronic disease and autoimmune disorders to new research revealing how early immune changes can develop into certain types of leukemia. In this particular episode, you’ll hear from de...
E55 Overcoming Self Doubt and Imposter Syndrome 11.03.2026 57:55
If you’ve ever experienced self-doubt, felt like you didn’t have what it takes, or were fearful of being “found out”, this episode is for you. We have all had the unfortunate experience of improperly doubting ourselves and our abilities to the extent that they had a negative impact on how we feel about ourselves and diminished our performance. Self-doubt and imposter syndrome can be paralyzing, bu...
E54 How to Set Your Personal Vision: Define What You Want to Accomplish in Life 04.03.2026 49:18
Can you easily and clearly answer the following question...WHAT do you want to achieve with your life? The question is simple, but it’s challenging for most of us to answer in a clear, concise, and convincing way. While we may have a rough or general idea of what we want to accomplish as human beings, very few of us can clearly articulate that in a way that is at the forefront of our minds and dri...
E53 How to Make Friends and Genuine Social Connections as an Adult 25.02.2026 55:44
Host: Christopher L. Camp, M.D., Creator & Guide | Mayo Clinic Human Optimization Project Guest: Katherine A. Meese, PhD, Researcher | Author | CEO - HuMargin Group – Nashville, TN If you are someone over the age of 22, you’ve likely noticed that it’s harder to make friends than it was when you were younger. Some of this is due to societal changes, but much of it is because life starts to pull...
E52 Daily Skin Care Routines We Should Be Doing for Life Long Skin Health 18.02.2026 56:23
Your skin is the largest organ in your body, and it does a lot more than just make you look good! It is our primary defense against the outside world and regulates many of our body's internal functions. Given the major role it plays in our health and overall performance, it is important that we take care of our skin to keep it healthy for as long as possible. Dr. Saryna Wyles is our expert guest...
E51 Things You Should Stop Doing to Improve Your Mental Strength 11.02.2026 56:37
Host: Christopher L. Camp, M.D., Creator & Guide | Mayo Clinic Human Optimization Project Guest: Amy Morin, LCSW, Psychotherapist / Mental Strength Coach / International Bestselling Author | Mentally Strong One of the biggest limiters of our mental strength is our very common (usually unintentional) struggle with self-sabotaging behaviors. Since we all feel too busy to do more, maybe the answe...
E50 How to Be More Creative and Get Yourself Back Outside the Box 04.02.2026 54:50
Host: Christopher L. Camp, M.D., Creator & Guide | Mayo Clinic Human Optimization Project Guest: Cal Aurand, Creative Director – Communications | Mayo Clinic – Rochester, MN "I wish I could be more creative” is a common trope that many of us say to ourselves. Unfortunately, that wish comes with the assumption that we aren’t creative, and we're here to disprove that notion to you today. What if...
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