DDx

Rare diseases are … rare … which makes even textbook cases difficult to diagnose. In this episode, we’ll talk about the…

Rare diseases are … rare … which makes even textbook cases difficult to diagnose. In this season, we’ll talk about the…

In this episode, we’ll dig into the different mechanisms by which gene therapy can potentially treat specific genetic…

Adeno-associated viral vectors, or AAVs, are the tiny shells of viruses. And today they are the most common vessels for…

Peek into the future of gene therapy and its capacity to treat – maybe eliminate – genetic diseases like cancers and…

Not all genetic variations are associated with threats or harms to human health. Some even  protect us, such as genetic…

In this episode, we explore some of the major scientific findings – like discovering DNA – that set the stage for the…

Take a deep dive into one of the most awe-inspiring medical innovations of our time: gene therapy. It’s comparable to some…

Few patients. A scarcity of literature. Working in rare disease can feel like you’re standing at the edge of an abyss with…

After a patient in his early 30s develops muscle weakness so severe he requires a wheelchair, he’s diagnosed with multiple…

A one-year old boy is brought to his doctor with a history of febrile seizures, odd movements, and developmental delay. His…

“Code blue, unit 305. Code blue, unit 305.” After an 8-year-old boy with recurrent episodes of rhabdomyolysis is…

Welcome back to DDx, a show about how doctors think. In Season 3, focused on rare disease, you’ll meet the doctors…

A common skin condition affects much more than a patient’s skin, and misinformation only exacerbates the stigma. This…

A dermatologist is paged to examine a rare condition. But something doesn’t add up. Head to Figure1.com/ddx, where you can…

What do you do when faced with a set of symptoms that has two contradictory courses of treatment? Head to Figure1.com/ddx,…

Unconscious bias can run so deep that patients and doctors alike can miss a potentially fatal diagnosis. Head to…

A patient presents with fever, swollen digits, and skin “the color of a red delicious apple.” She’s been scratching so hard…

A young man’s near-death experience results in a very puzzling diagnosis on the season finale of DDx.

Chronic vomiting, a flushed complexion, and acute agitation: can cannabis be the cause? A growing consensus among doctors…

Welcome to DDx, an original podcast by Figure 1 about how doctors think.  On episode 1, host and emergency doctor Raj…

A patient says she feels fine. A quick-thinking doctor arrives at a dire and uncommon diagnosis. Then it happens again. And…

A patient with an acute subdural hematoma presents with no sign of head trauma. The search for an answer almost overlooks an…

A 19-year-old with sickle cell disease is well-known to ER doctors as a “frequent flyer”. Every time they see her it’s due to…