Medical Digest & Congress Report

Prof. Elmir Omerovic presents key results from the SWITCH SWEDEHEART trial at the ESC Congress 2026, evaluating the safety and efficacy of switching from ticagrelor to prasugrel in patients with acute coronary syndromes. Video: https://medicaldigest.org/scientific-contents/interview:switch-swedeheart-switching-ticagrelor-prasugrel-acs

Prof. Piotr Ponikowski discusses the critical gap between heart failure guidelines and real-world clinical practice, exploring the missing pieces needed for successful guideline-directed medical therapy (GDMT) implementation. Video: https://medicaldigest.org/scientific-contents/interview:guidelines-clinical-impact-key-takeaways-gdmt-implementation-report-esc-2026

Prof. Shelley Zieroth addresses the critical importance of early, in-hospital initiation of guideline-directed medical therapy for heart failure at the ESC Congress 2026, highlighting practical strategies to improve patient outcomes during post-discharge transition. Video: https://medicaldigest.org/scientific-contents/interview:start-early-start-hospital-translating-heart-failure-guidelines-practi...

Prof. Felix Mahfoud summarizes the main highlights and key clinical takeaways from the ESC Congress 2026, showcasing practice-changing trial results, new guidelines, and breakthroughs across AI, cardiometabolic disease, and interventional cardiology. Video: https://medicaldigest.org/scientific-contents/interview:main-highlights-and-key-clinical-takeaways-esc-2026

Prof. Giuseppe Rosano addresses key challenges in implementing guideline-directed medical therapy at the ESC Congress 2026, exploring strategies to bridge the gap between clinical recommendations and real-world cardiovascular care. Video: https://medicaldigest.org/scientific-contents/interview:guidelines-clinical-impact-gdmt-implementation

Prof. Boyoung Joung presents findings from the landmark SINGLE-AF trial at the ESC Congress 2026. The study demonstrates that direct oral anticoagulants (DOACs) significantly reduce stroke risk in atrial fibrillation patients at intermediate risk without increasing major bleeding. Video: https://medicaldigest.org/scientific-contents/interview:single-af-anticoagulation-atrial-fibrillation-intermedi...

Prof. Ashkan Shoamanesh presents key findings from the ENRICH-AF trial at the ESC Congress 2026. The study evaluates whether edoxaban safely reduces stroke risk in high-risk atrial fibrillation patients with a history of intracranial hemorrhage, highlighting crucial trade-offs between ischemic stroke prevention and major bleeding risks. Video: https://medicaldigest.org/scientific-contents/intervie...

Prof. Kristin Newby breaks down the new 5th Universal Definition of Myocardial Infarction at the ESC Congress 2026, highlighting refined diagnostic criteria and global clinical consensus. Video: https://medicaldigest.org/scientific-contents/interview:5th-universal-definition-myocardial-infarction

Prof. Matthias Wilhelm outlines the updated 2026 ESC Guidelines on Cardiac Rehabilitation at the ESC Congress 2026, focusing on personalized training and modern secondary prevention strategies. Video: https://medicaldigest.org/scientific-contents/interview:2026-esc-guidelines-cardiac-rehabilitation

Professor Daisy Acosta delivers an essential expert overview on the shifting landscape of dementia prevalence across Latin America, building on crucial insights from the 10/66 studies. This concise brief highlights the unexpected increase in dementia prevalence over the past two decades across multiple catchment sites, contrasting sharply with the declining trends observed in high-income countries...

Professor Takaomi C. Saido, world renowned scientist, delivers a comprehensive expert overview on the current state of Alzheimer's disease research, moving past traditional models to explore groundbreaking therapeutic targets. This concise brief highlights the mechanisms behind approved disease-modifying therapies, the crucial role of neprilysin and somatostatin receptor in amyloid clearance,...

Dr. James Douketis delivers an essential overview of the key highlights from the newly updated ISTH guidelines and guidance documents at the ISTH 2026 Congress. This targeted brief focuses on practical, evidence-based clinical recommendations, highlighting two major clinical updates: Surgical and Procedural Bleed Risk Stratification for Anticoagulated Patients Undergoing Planned Surgery – A refine...

Dr. Zsuzsanna Bagoly presents the highly anticipated updated clinical recommendations for the diagnosis and classification of Factor XIII (FXIII) deficiencies at the ISTH 2026 Congress. This essential brief outlines the revised diagnostic algorithms, standardized laboratory assays, and clear classification pathways designed to improve the detection and management of this underdiagnosed, life-threa...

Dr. Marco Donadini highlights the next generation of antithrombotic therapies at the ISTH 2026 Congress, featuring these breakthrough presentations: - A Synthetic, Allosteric, Highly Selective, Reversible Inhibitor of Human Factor XIa for Venous and Lung (Cancer-Associated) Thrombosis – Umesh Desai (Richmond, US) - EXocite ACTive site (EXACT) Inhibitors as Potent RNA Aptamer-Based Anticoagulants T...

Dr. Kerstin de Wit highlights critical updates on anticoagulant-associated bleeding risks, management, and reversal strategies presented at the ISTH 2026 Congress, featuring the following key studies: - Perioperative Anticoagulation Management and Outcomes in Thrombotic Antiphospholipid Syndrome: A Single-Center Cohort Study – Miguel Paquette (Ottawa, Canada) - The Incidence and Outcomes of LMWH-R...

Dr. Oliver Schlager outlines the acute and long-term management of severe deep vein thrombosis (DVT) in alignment with the ESVM VTE Guidelines at the ISTH 2026 Congress. This brief highlights key recommendations for early intervention, tailored anticoagulation duration, and strategies to minimize the risk of post-thrombotic syndrome (PTS). Video: https://medicaldigest.org/scientific-contents/inter...

Dr. Fionnuala Ní Áinle presents an essential overview of the latest ISTH Guidelines and Guidance Documents at the ISTH 2026 Congress. This brief highlights key clinical recommendations, the methodological rigor behind the guidelines, and practical implementation strategies to standardize care in thrombosis and hemostasis globally. Video: https://medicaldigest.org/scientific-contents/interview:intr...

Dr. Darko Antic presents key insights into the complex management of cancer-associated thrombosis (CAT) and hemostasis at the ISTH 2026 Congress. This brief highlights the latest clinical evidence on anticoagulation strategies, balancing bleeding versus recurrent thrombotic risks, and customizing treatment pathways for oncological patients. Video: https://medicaldigest.org/scientific-contents/inte...

Dr. Aurélien Delluc highlights key advancements in Venous Thromboembolism (VTE) diagnosis from the ISTH 2026 Congress. Video: https://medicaldigest.org/scientific-contents/interview:vte-diagnosis-whats-new

Dr. Rebecca Edelmayer presents an inspiring overview of the latest breakthroughs and novelties in the treatment of Alzheimer's disease at the AAIC 2026 Congress. Video: https://medicaldigest.org/scientific-contents/interview:novelties-treatment-alzheimers-disease

Dr. Courtney Kloske delivers a highly anticipated expert overview of the most impactful breakthroughs and scientific updates presented at the AAIC 2026 Congress. This concise brief highlights accelerated advances in early diagnostics, emerging multi-omics approaches, key clinical trial outcomes, and global initiatives shaping the future of Alzheimer's and dementia research. Video: https://medi...

Dr. Emanuel Della Torre discusses the clinical evidence behind targeting CD19+ B-cells in IgG4-related disease in a post-congress interview following EULAR 2026. This recap focuses on the therapeutic impact of these strategies, underlying immunological mechanisms, and the long-term management implications for patients in clinical practice. Video: https://medicaldigest.org/scientific-contents/inter...

Professor Laura C. Coates highlights the rapidly evolving landscape of state-of-the-art treatments for psoriatic arthritis (PsA) in a post-congress interview following EULAR 2026. This recap focuses on personalized management pathways, novel targeted therapies, and strategic frameworks aimed at optimizing long-term patient outcomes. Video: https://medicaldigest.org/scientific-contents/interview:st...

Professor Elena Nikiphorou discusses the ongoing paradigm shift in rheumatoid arthritis (RA), presented at the EULAR 2026 Congress. This recap focuses on novel insights into RA pathogenesis and explores the promising therapeutic pipeline, highlighting how these scientific advancements are translating into more targeted, effective management strategies for clinical practice. Video: https://medicald...

Professor Oliver Distler dives into the complex landscape of systemic sclerosis (SSc), presented at the EULAR 2026 Congress. This recap focuses on recent breakthroughs in deciphering SSc pathogenesis, identifying and managing critical comorbidities, and evaluating emerging therapeutic strategies that pave the way for highly targeted clinical treatments. Video: https://medicaldigest.org/scientific-...